Shantelle L. LaFayette

McGill University Health Centre — Canada

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index690citations12works0.02yr avg
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Research Topics

Bacterial biofilms and quorum sensing(6), Cystic Fibrosis Research Advances(6), Immune Response and Inflammation(3), Inhalation and Respiratory Drug Delivery(3), Antibiotic Resistance in Bacteria(2)

Publications12 total

LasR-deficient Pseudomonas aeruginosa variants increase airway epithelial mICAM-1 expression and enhance neutrophilic lung inflammation
PLoS Pathogens·2021· 32 citedOpen Access
Quorum Sensing Down-Regulation Counteracts the Negative Impact of Pseudomonas aeruginosa on CFTR Channel Expression, Function and Rescue in Human Airway Epithelial Cells
Frontiers in Cellular and Infection Microbiology·2017· 25 citedOpen Access
Differential Contribution of the Aryl-Hydrocarbon Receptor and Toll-Like Receptor Pathways to IL-8 Expression in Normal and Cystic Fibrosis Airway Epithelial Cells Exposed to Pseudomonas aeruginosa
Frontiers in Cell and Developmental Biology·2016· 15 citedOpen Access
Quorum‐sensing inhibition abrogates the deleterious impact of <i>Pseudomonas aeruginosa</i> on airway epithelial repair
The FASEB Journal·2016· 49 citedOpen Access
The impact of pseudomonas aeruginosa genetic adaptation to the cystic fibrosis airway on inflammation and bacterial persistence
eScholarship@McGill (McGill)·2016Open Access
Staphylococcus aureus Inhibits IL-8 Responses Induced by Pseudomonas aeruginosa in Airway Epithelial Cells
PLoS ONE·2015· 34 citedOpen Access
Cystic fibrosis–adapted <i>Pseudomonas aeruginosa</i> quorum sensing <i>lasR</i> mutants cause hyperinflammatory responses
Science Advances·2015· 127 citedOpen Access
The Level of p38α Mitogen-Activated Protein Kinase Activation in Airway Epithelial Cells Determines the Onset of Innate Immune Responses to Planktonic and Biofilm Pseudomonas aeruginosa
The Journal of Infectious Diseases·2013· 28 citedOpen Access
Mucoid Pseudomonas aeruginosa caused by mucA mutations result in activation of TLR2 in addition to TLR5 in airway epithelial cells
Biochemical and Biophysical Research Communications·2012· 22 cited
PKC Signaling Regulates Drug Resistance of Candida albicans and Saccharomyces cerevisiae via Divergent Circuitry Composed of the MAPK Cascade, Calcineurin and Hsp90
Library and Archives Canada (Government of Canada)·2011
PKC Signaling Regulates Drug Resistance of the Fungal Pathogen Candida albicans via Circuitry Comprised of Mkc1, Calcineurin, and Hsp90
PLoS Pathogens·2010· 330 citedOpen Access
Gene Expression and Evolution of Antifungal Drug Resistance
Antimicrobial Agents and Chemotherapy·2009· 28 citedOpen Access

Frequent Co-authors

Dao Nguyen(8), Simon Rousseau(7), Trevor Beaudoin(4), Emmanuelle Brochiero(3), Geoffrey A. McKay(3), Daniel Houle(2), Manon Ruffin(2), Émilie Maillé(2), Lucie Roussel(2), Cathy Collins(1), Aimee K. Zaas(1), Wiley A. Schell(1), Marisol Betancourt-Quiroz(1), A. A. Leslie Gunatilaka(1), John R. Perfect(1), Leah E. Cowen(1), Gabriella Wojewodka(1), Danuta Radzioch(1), Lucas R. Hoffman(1), Jane L. Burns(1)