Aline T. Marinho

MRC Prion Unit — United Kingdom

Medicine · Health Sciences

10h-index281citations29works0.52yr avg
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Research Topics

HIV/AIDS drug development and treatment(14), HIV Research and Treatment(8), Paraoxonase enzyme and polymorphisms(5), Pneumocystis jirovecii pneumonia detection and treatment(4), Influenza Virus Research Studies(3)

Publications29 total

Intracellular trafficking SNARE protein, syntaxin-6, modifies prion cellular phenotypes and risk of disease development in vivo
Acta Neuropathologica·2025· 1 citedOpen Access
Intracellular Trafficking SNARE Protein, Syntaxin-6, is a Modifier of Prion and Tau Pathogenesis <i>in vivo</i> and in Cellular Models
2025Open Access
Panorama atual da pesquisa com animais e coronavírus (Sars-CoV2): Modelos, aspectos de legislação e biossegurança
Imprensa Universitária eBooks·2022
The 2-hydroxy-nevirapine metabolite as a candidate for boosting apolipoprotein A1 and for modulating anti-HDL antibodies
Pharmacological Research·2021· 3 cited
Highly infectious prions are not directly neurotoxic
Proceedings of the National Academy of Sciences·2020· 39 citedOpen Access
Inactivating mutations and X-ray crystal structure of the tumor suppressor OPCML reveal cancer-associated functions
Nature Communications·2019· 16 citedOpen Access
Anti-tumorigenic and Platinum-Sensitizing Effects of Apolipoprotein A1 and Apolipoprotein A1 Mimetic Peptides in Ovarian Cancer
Frontiers in Pharmacology·2019· 26 citedOpen Access
Singularities of nevirapine metabolism: from sex-dependent differences to idiosyncratic toxicity
Drug Metabolism Reviews·2019· 10 cited
Teaching an old drug new tricks: re-profiling of nevirapine as an hdl modulator
Revista de Estudos Anglo-Portugueses/Journal of Anglo-Portuguese Studies·2018Open Access
Hepatocyte spheroids as a competent in vitro system for drug biotransformation studies: nevirapine as a bioactivation case study
Archives of Toxicology·2016· 28 cited
Nevirapine modulation of paraoxonase-1 in the liver: An in vitro three-model approach
European Journal of Pharmaceutical Sciences·2015· 7 cited
Anti-histone antibodies in HIV-infected patients on Nevirapine-containing ANTIRETROVIRAL THERAPY
Clinical Therapeutics·2015· 1 citedOpen Access
Sex differences in hepatic and intestinal contributions to nevirapine biotransformation in rats
Chemico-Biological Interactions·2015· 8 cited
Sex differences in apolipoprotein A1 and nevirapine‐induced toxicity
Journal of the International AIDS Society·2014· 3 citedOpen Access
Monitoring of the lactonase activity of paraoxonase‐1 enzyme in HIV‐1‐infection
Journal of the International AIDS Society·2014· 6 citedOpen Access
Paraoxonase as part of endogenous free-radical scavenging system in zebrafish
Toxicology Letters·2014
PON-1 activity as a protective player in nevirapine hepatotoxicity: Data comparison in 2D and 3D cell cultures
Toxicology Letters·2014· 1 cited
Thiol status in HIV-infected patients: The effect of nevirapine metabolism
Toxicology Letters·2014
Sex differences in hepatic and intestinal contributions for nevirapine biotransformation
Toxicology Letters·2014
Development and validation of an HPLC-UV method for quantifying nevirapine and its main phase I metabolites in human blood
Analytical Methods·2014· 10 cited
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Frequent Co-authors

Sofia A. Pereira(21), Alexandra M. M. Antunes(16), Emília C. Monteiro(16), M. Matilde Marques(15), Umbelina Caixas(12), Clara G. Dias(11), Joana P. Miranda(8), Pedro F. Pinheiro(7), Teresa Branco(5), Shrika G. Harjivan(4), Nádia M. Grilo(3), Christian Schmidt(3), John Collinge(3), Matilde Castro(3), Ana L. A. Godinho(2), M. Conceição Oliveira(2), Haonan Lu(2), Hani Gabra(2), Chiara Recchi(2), Catarina Charneira(2)