Isao Asaka

Kyoto University — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

20h-index3.0kcitations45works1.02yr avg
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Research Topics

Pluripotent Stem Cells Research(16), CRISPR and Genetic Engineering(9), Ginseng Biological Effects and Applications(5), Renal and related cancers(4), Biomedical Ethics and Regulation(4)

Publications45 total

Secondary Publication: Proposal for Points of Consideration for Pluripotent Stem Cell Culture
In Vitro Cellular & Developmental Biology - Animal·2024· 1 citedOpen Access
A disease-specific iPS cell resource for studying rare and intractable diseases
Inflammation and Regeneration·2023· 15 citedOpen Access
Additional file 2 of A disease-specific iPS cell resource for studying rare and intractable diseases
Figshare·2023Open Access
Additional file 1 of A disease-specific iPS cell resource for studying rare and intractable diseases
Figshare·2023Open Access
<scp>iPS</scp> cells from <scp>Chediak‐Higashi</scp> syndrome patients recapitulate the giant granules in myeloid cells
Pediatrics International·2022· 2 cited
Investigation of the molecular causes underlying physical abnormalities in Diamond‐Blackfan anemia patients with <i>RPL5</i> haploinsufficiency
Pathology International·2021· 5 cited
Generation of two human induced pluripotent stem cell lines derived from two X-linked adrenoleukodystrophy patients with ABCD1 mutations
Stem Cell Research·2021· 8 citedOpen Access
Deterioration of phagocytosis in induced pluripotent stem cell-derived retinal pigment epithelial cells established from patients with retinitis pigmentosa carrying Mer tyrosine kinase mutations
Experimental Eye Research·2021· 11 cited
In Vitro Disease Modeling of Hermansky-Pudlak Syndrome Type 2 Using Human Induced Pluripotent Stem Cell-Derived Alveolar Organoids
Stem Cell Reports·2019· 18 citedOpen Access
Alveolar Epithelial Type 2 Cell Dysfunction in Hermansky-Pudlak Syndrome Type 2 Patient-Derived Induced Pluripotent Stem Cells
2019
In Vitro Disease Modeling of Hermansky-Pudlak Syndrome Type 2 Using Human Induced Pluripotent Stem Cell-Derived Alveolar Organoids
Stem Cell Reports·2019· 96 citedOpen Access
Pluripotent Stem Cell Model of Nakajo-Nishimura Syndrome Untangles Proinflammatory Pathways Mediated by Oxidative Stress
Stem Cell Reports·2018· 37 citedOpen Access
Reduction of lipid accumulation rescues Bietti’s crystalline dystrophy phenotypes
Proceedings of the National Academy of Sciences·2018· 66 citedOpen Access
Human AK2 links intracellular bioenergetic redistribution to the fate of hematopoietic progenitors
Biochemical and Biophysical Research Communications·2018· 19 citedOpen Access
Insulin‐producing cells derived from ‘induced pluripotent stem cells’ of patients with fulminant type 1 diabetes: Vulnerability to cytokine insults and increased expression of apoptosis‐related genes
Journal of Diabetes Investigation·2017· 31 citedOpen Access
Pluripotent stem cell models of Blau syndrome reveal an IFN-γ–dependent inflammatory response in macrophages
Journal of Allergy and Clinical Immunology·2017· 51 citedOpen Access
BMP-SMAD-ID promotes reprogramming to pluripotency by inhibiting p16/INK4A-dependent senescence
Proceedings of the National Academy of Sciences·2016· 114 citedOpen Access
Identification of a High‐Frequency Somatic <i>NLRC4</i> Mutation as a Cause of Autoinflammation by Pluripotent Cell–Based Phenotype Dissection
Arthritis & Rheumatology·2016· 134 cited
Identification of MMP1 as a novel risk factor for intracranial aneurysms in ADPKD using iPSC models
Scientific Reports·2016· 38 citedOpen Access
Impaired adipogenic capacity in induced pluripotent stem cells from lipodystrophic patients with BSCL2 mutations
Metabolism·2016· 28 cited
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Frequent Co-authors

Shinya Yamanaka(17), Tatsutoshi Nakahata(13), Megumu K. Saito(12), Akira Watanabe(11), Akira Niwa(10), Kazutoshi Takahashi(8), Kayoko Tsukita(6), Keisuke Okita(6), Ayako Nagahashi(6), Mitsujiro Osawa(6), Kazuwa Nakao(6), Akitsu Hotta(6), Naohiro Egawa(5), Naoki Yahata(5), Takashi Aoi(5), Hiroyuki Hioki(5), Takeshi Kaneko(5), Takashi Asada(5), Haruhisa Inoue(5), Kenji Osafune(5)