Martin J. Humphries

Wellcome Centre for Cell-Matrix Research — United Kingdom

Medicine · Health Sciences

101h-index32.1kcitations611works0.52yr avg
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Research Topics

Cell Adhesion Molecules Research(348), Cellular Mechanics and Interactions(116), Protease and Inhibitor Mechanisms(81), Monoclonal and Polyclonal Antibodies Research(72), Connective tissue disorders research(40)

Publications610 total

A TRPV4-dependent calcium signaling axis regulates lamellipodial actin architecture to promote cell migration
Current Biology·2026Open Access
The hypoxic ECM and neutrophils in MIBC immunotherapy resistance
Nature Reviews Urology·2025
Oscillatory and elevated flow distinctly regulate gene expression in human coronary artery endothelial cells
2025Open Access
Author response: Matrix-associated extracellular vesicles modulate human smooth muscle cell adhesion and directionality by presenting collagen VI
2025Open Access
Matrix-associated extracellular vesicles modulate human smooth muscle cell adhesion and directionality by presenting collagen VI
eLife·2025Open Access
Author response: Matrix-associated extracellular vesicles modulate smooth muscle cell adhesion and directionality by presenting collagen VI
2025Open Access
Matrix-associated extracellular vesicles modulate smooth muscle cell adhesion and directionality by presenting collagen VI
2025Open Access
Regulation of reticular adhesions by KANK2 and talin2 in two melanoma cell lines
2025· 1 citedOpen Access
The RNA splicing factor PRPF8 is required for left-right organiser cilia differentiation and determination of cardiac left-right asymmetry via regulation of Arl13b splicing
2025Open Access
Inhibitory TIGIT signalling is dependent on T cell receptor activation
2025Open Access
2334 A pan-cancer characterisation of the hypoxic extracellular matrix identifies a gene signature predictive of radiotherapy benefit
Radiotherapy and Oncology·2025
Hypoxia-induced extracellular matrix changes are conserved in cancer and directly impact radiotherapy benefit
2025· 2 citedOpen Access
A TRPV4-dependent calcium signaling axis governs lamellipodial actin architecture to promote cell migration
2025Open Access
KANK2 at focal adhesion regulates their maintenance and dynamics, while at fibrillar adhesions it influences cell migration via microtubule-dependent mechanism
2025· 1 citedOpen Access
Antineoplastic Potential and Other Possible Uses of Swainsonine and Related Compounds
2024· 1 cited
Fibronectin Receptors on NK Cells
2024
The extracellular matrix component perlecan/HSPG2 regulates radioresistance in prostate cancer cells
Frontiers in Cell and Developmental Biology·2024· 4 citedOpen Access
Abstract 1812 Vinculin Expression and Substrate Stiffness Regulate Proliferation, Activin-A Secretion and Mechanosensory Gene Expression in Mesenchymal Stem Cells
Journal of Biological Chemistry·2024Open Access
Author Correction: Systemically administered wound-homing peptide accelerates wound healing by modulating syndecan-4 function
Nature Communications·2024Open Access
Systemically administered wound-homing peptide accelerates wound healing by modulating syndecan-4 function
Nature Communications·2023· 19 citedOpen Access
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Frequent Co-authors

Kenneth M. Yamada(11), Jonathan D. Humphries(10), A. Paul Mould(10), Janet A. Askari(9), Kenneth Olden(8), Adam Byron(6), Akira Komoriya(6), David Knight(4), Steven K. Akiyama(4), Mark D. Bass(3), Zohreh Mostafavi‐Pour(3), Christoph Ballestrem(2), Elizabeth A. Wayner(2), Andrés J. Garcı́a(2), Mark R. Morgan(2), Edward R. Horton(2), Sue E. Craig(2), Patrick T. Caswell(2), Maddy Parsons(2), Kurt I. Anderson(2)