Shao‐Yu Fang

Second Military Medical University — China

Biochemistry, Genetics and Molecular Biology · Life Sciences

11h-index276citations21works3.62yr avg
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Research Topics

CRISPR and Genetic Engineering(5), Synthesis and biological activity(3), Virus-based gene therapy research(3), CAR-T cell therapy research(3), Cancer Immunotherapy and Biomarkers(2)

Publications21 total

Design, Synthesis, and Protective Effect Evaluation on Myocardial Ischemia of New Triazole Aldehyde Dehydrogenase 2 Activators
ACS Medicinal Chemistry Letters·2025Open Access
Cas12a-knock-in mice for multiplexed genome editing, disease modelling and immune-cell engineering
Nature Biomedical Engineering·2025· 18 citedOpen Access
<i> Helicobacter pylori</i> Infection and Non-steroidal Anti-inflammatory Drugs Mediated Gastric Ulcer: Insights into Efficacy and Strategies for Gastroprotective Treatments and Disease Management
Jundishapur Journal of Microbiology·2025Open Access
65 High-fidelity enhanced AsCas12a knock-in mice for efficient multiplexed gene editing, disease modeling and orthogonal immunogenetics
Regular and Young Investigator Award Abstracts·2024Open Access
High-fidelity enhanced AsCas12a knock-in mice for efficient multiplexed gene editing, disease modeling and orthogonal immunogenetics
2024Open Access
CTLA-4 tail fusion enhances CAR-T antitumor immunity
Nature Immunology·2023· 45 citedOpen Access
Applications of <scp>CRISPR</scp> technology in cellular immunotherapy
Immunological Reviews·2023· 11 citedOpen Access
CTLA-4 tail fusion enhances CAR-T anti-tumor immunity
2023· 3 citedOpen Access
Cas12a/Cpf1 knock-in mice enable efficient multiplexed immune cell engineering
2023· 5 citedOpen Access
Skp2-mediated Zeb1 expression facilitates cancer migration by a ubiquitination-independent pathway
Life Sciences·2022· 10 cited
Corrigendum to ‘Synthesis and biological evaluation of 7-methoxy-1-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-benzo[e]indazoles as new colchicine site inhibitors’ [Bioorgan. Med. Chem. Lett. 29 (2019) 2632–2634]
Bioorganic & Medicinal Chemistry Letters·2021
Association of patient-to-emergency department staff ratio with the incidence of cardiac arrest: A retrospective cohort study
Signa Vitae·2021· 3 citedOpen Access
The discovery of novel small molecule allosteric activators of aldehyde dehydrogenase 2
European Journal of Medicinal Chemistry·2020· 11 citedOpen Access
Curcumol Suppresses Triple-negative Breast Cancer Metastasis by Attenuating Anoikis Resistance <i>via</i> Inhibition of Skp2-mediated Transcriptional Addiction
Anticancer Research·2020· 22 citedOpen Access
Reduction in MicroRNA-4488 Expression Induces NFκB Translocation in Venous Endothelial Cells Under Arterial Flow
Cardiovascular Drugs and Therapy·2020· 9 cited
Traditional versus blended CPR training program: A randomized controlled non-inferiority study
Scientific Reports·2020· 47 citedOpen Access
Identification of CHD4-β1 integrin axis as a prognostic marker in triple-negative breast cancer using next-generation sequencing and bioinformatics
Life Sciences·2019· 33 cited
Synthesis and biological evaluation of 7-methoxy-1-(3,4,5-trimethoxyphenyl)-4,5-dihydro-2H-benzo[e]indazoles as new colchicine site inhibitors
Bioorganic & Medicinal Chemistry Letters·2019· 12 citedOpen Access
1-Phenyl-dihydrobenzoindazoles as novel colchicine site inhibitors: Structural basis and antitumor efficacy
European Journal of Medicinal Chemistry·2019· 13 citedOpen Access
Impact of BMI1 expression on the apoptotic effect of paclitaxel in colorectal cancer.
PubMed·2019· 12 citedOpen Access
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Frequent Co-authors

Sidi Chen(7), Hanbing Cao(6), Ryan D. Chow(6), Kaiyuan Tang(6), Medha Majety(6), Matthew B. Dong(6), Ruolan Zhou(6), Canhui Zheng(6), Qingsen Zhang(5), Xiaoyu Zhou(5), Mei‐Ren Pan(4), Chi‐Wen Luo(4), Liqun Zhou(4), Erica Vandenbulcke(4), Andrew Du(4), Johanna Shen(4), Jerry Zhou(4), Krista Chen(4), Jiapeng Guo(4), Paul Renauer(3)