Helen M. Rowe

Queen Mary University of London — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

18h-index3.8kcitations30works0.02yr avg
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Research Topics

CRISPR and Genetic Engineering(17), Chromosomal and Genetic Variations(16), Genomics and Chromatin Dynamics(7), Epigenetics and DNA Methylation(5), Immunotherapy and Immune Responses(5)

Publications30 total

Epigenetic lockdown of type I interferon sensing and signalling in human pluripotent cells
2025Open Access
Co-option of endogenous retroviruses through genetic escape from TRIM28 repression
Cell Reports·2023· 21 citedOpen Access
Shrouded in genomic heterochromatin are ancient viral-like elements that could jump
Open Access Government·2023Open Access
A satellite DNA array barcodes chromosome 7 and regulates totipotency via ZFP819
Science Advances·2022· 9 citedOpen Access
Satellite DNA arrays barcode chromosomes to regulate genes
Open Access Government·2022Open Access
Co-option of endogenous retroviruses through genetic escape from TRIM28 repression
2022· 2 citedOpen Access
Editorial Overview: Endogenous Retroviruses in Development and Disease
Viruses·2020· 1 citedOpen Access
The HUSH complex is a gatekeeper of type I interferon through epigenetic regulation of LINE-1s
Nature Communications·2020· 158 citedOpen Access
Host Gene Regulation by Transposable Elements: The New, the Old and the Ugly
Viruses·2020· 35 citedOpen Access
A nuclear licence to silence transposons
EMBO Reports·2019· 4 citedOpen Access
<scp>KAP</scp> 1 regulates endogenous retroviruses in adult human cells and contributes to innate immune control
EMBO Reports·2018· 123 citedOpen Access
The HUSH complex cooperates with TRIM28 to repress young retrotransposons and new genes
Genome Research·2018· 218 citedOpen Access
Adeno-associated virus Rep proteins antagonize phosphatase PP1 to counteract KAP1 repression of the latent viral genome
Proceedings of the National Academy of Sciences·2018· 31 citedOpen Access
Cancer cells, on your histone marks, get SETDB1, silence retrotransposons, and go!
The Journal of Cell Biology·2017· 12 citedOpen Access
Epigenetic control of retrotransposons in adult tissues: implications for immune regulation
Current Opinion in Virology·2017· 9 cited
Transposable Elements and Their KRAB-ZFP Controllers Regulate Gene Expression in Adult Tissues
Developmental Cell·2016· 233 citedOpen Access
A Large-Scale Functional Screen to Identify Epigenetic Repressors of Retrotransposon Expression
Methods in molecular biology·2016· 3 citedOpen Access
Retrotransposons shape species-specific embryonic stem cell gene expression
Retrovirology·2015· 82 citedOpen Access
Loss of transcriptional control over endogenous retroelements during reprogramming to pluripotency
Genome Research·2014· 101 citedOpen Access
Global and Stage Specific Patterns of Krüppel-Associated-Box Zinc Finger Protein Gene Expression in Murine Early Embryonic Cells
PLoS ONE·2013· 47 citedOpen Access
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Frequent Co-authors

Didier Trono(10), Rocio Enriquez-Gasca(6), Poppy A. Gould(6), Christopher H.C. Tie(5), Lucía Conde(5), Javier Herrero(5), Gabriela Ecco(4), Luisa Robbez‐Masson(4), Hale Tunbak(4), Robert J. Gifford(4), Pierre V. Maillard(3), Adamandia Kapopoulou(3), Liane Fernandes(3), James H. Holt(3), Luciene Lopes(3), Benny Chain(3), Mary Collins(3), Todd S. Macfarlan(2), Samuel L. Pfaff(2), Johan Jakobsson(2)