Nikki K. Lytle

Medical College of Wisconsin — United States

Medicine · Health Sciences

21h-index2.9kcitations52works0.22yr avg
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Research Topics

Pancreatic and Hepatic Oncology Research(21), Cancer Cells and Metastasis(12), Cancer Research and Treatments(6), Cancer, Hypoxia, and Metabolism(5), Microtubule and mitosis dynamics(4)

Publications52 total

Mutant and Wild-type RAS Crosstalk and Stoichiometric Deficiencies are Determinants of Sensitivity to Targeted Therapies in KRASG12R Pancreatic Ductal Adenocarcinoma
Cancer Research·2025Open Access
Natural history of SPP1 signaling in NF1 tumors
npj Precision Oncology·2025Open Access
Abstract A010: Chemotherapy-associated liver damage accelerates pancreatic cancer liver metastasis
Cancer Research·2025
Abstract B008: Ex-vivo organotypic tumor model of metastatic core biopsy serve as a pragmatic platform for real-time personalized therapy in pancreatic adenocarcinoma
Cancer Research·2025
AI-Derived Electronic Tumor Marker (e19-9) Can Measure Treatment Response and Outcomes in CA19-9 Non-Producers with Pancreatic Ductal Adenocarcinoma
2025Open Access
The molecular chronology of mammary epithelial cell fate switching
2024· 2 citedOpen Access
Abstract LB223: The molecular landscape of injury-induced mammary epithelial cell fate switching
Cancer Research·2024
Abstract A069: The molecular landscape of injury-induced mammary epithelial cell fate switching
Cancer Research·2024
MEK Inhibitor Therapy in Pancreatic Ductal Adenocarcinoma with KRAS G12R Mutation
SSRN Electronic Journal·2024Open Access
Single-cell mapping identifies MSI+ cells as a common origin for diverse subtypes of pancreatic cancer
Cancer Cell·2023· 17 citedOpen Access
Smarcd3 is an epigenetic modulator of the metabolic landscape in pancreatic ductal adenocarcinoma
Nature Communications·2023· 21 citedOpen Access
Atm Or Chek2 Alterations as Potential Biomarkers of Improved Outcomes with Irinotecan: Real-World Analysis of Advanced Pancreatic Ductal Adenocarcinoma
SSRN Electronic Journal·2023· 1 citedOpen Access
Illuminating histidine phosphorylation in the pancreatic tumor microenvironment
2022· 4 citedOpen Access
Metaplasia‐induced Epithelial Heterogeneity Directs Pancreatic Injury and Tumorigenesis
The FASEB Journal·2022
Single-Cell Transcriptomic and Epigenetic Analyses of Mouse Mammary Development Starting with the Embryo
Methods in molecular biology·2022· 2 citedOpen Access
Eicosanoids in the Pancreatic Tumor Microenvironment—A Multicellular, Multifaceted Progression
Gastro Hep Advances·2022· 8 citedOpen Access
Author Correction: Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring
Nature·2021· 3 citedOpen Access
Eicosanoids in the pancreatic tumor microenvironment – a multicellular, multifaceted progression
2021Open Access
Single-Cell Transcriptomics Reveals a Conserved Metaplasia Program in Pancreatic Injury
Gastroenterology·2021· 106 citedOpen Access
264 METAPLASIA-INDUCED EPITHELIAL HETEROGENEITY DIRECTS PANCREATIC TISSUE INJURY AND RECOVERY
Gastroenterology·2021· 1 cited
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Frequent Co-authors

Tannishtha Reya(19), Geoffrey M. Wahl(17), Kathleen E. DelGiorno(10), Andrew M. Lowy(10), Zhibo Ma(10), Uri Manor(8), Raymond G. Fox(8), Detlev Boison(6), Sammy Weiser Novak(6), Razia F. Naeem(6), L. Paige Ferguson(5), Nirakar Rajbhandari(5), Marcie Kritzik(5), Jeevisha Bajaj(5), Claire S. Koechlein(5), Christopher Dravis(5), Yu Shi(4), Maya Ridinger-Saison(4), Galina Erikson(4), Linjing Fang(4)