Jan Rheinberger

University of Groningen — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index843citations62works1.52yr avg
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Research Topics

Lipid Membrane Structure and Behavior(15), Ion channel regulation and function(14), Advanced Electron Microscopy Techniques and Applications(8), Photoreceptor and optogenetics research(6), SARS-CoV-2 and COVID-19 Research(5)

Publications62 total

Structural basis of the obligatory exchange mode of human neutral amino acid transporter ASCT2
Nature Communications·2024· 6 citedOpen Access
Single particle cryo-EM of ASCT2 in lipid nanodiscs under Na+-depleted conditions
EMPIAR dataset·2024Open Access
Single particle cryo-EM of ASCT2 in lipid nanodiscs with bound glutamine and Na+ ions
EMPIAR dataset·2024Open Access
Think like a channel, act like a carrier
Biophysical Journal·2024Open Access
Structures of a sperm-specific solute carrier gated by voltage and cAMP
Nature·2023· 16 citedOpen Access
Expulsion mechanism of the substrate-translocating subunit in ECF transporters
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Expulsion mechanism of the substrate-translocating subunit in ECF transporters
University of Groningen research database (University of Groningen / Centre for Information Technology)·2023Open Access
cAMP-bound SpSLC9C1 in lipid nanodiscs
EMPIAR dataset·2023· 1 citedOpen Access
Expulsion mechanism of the substrate-translocating subunit in ECF transporters
Nature Communications·2023· 14 citedOpen Access
cGMP-bound SpSLC9C1 in lipid nanodiscs
EMPIAR dataset·2023Open Access
Ligand-free SpSLC9C1 in detergent
EMPIAR dataset·2023Open Access
Ligand-free SpSLC9C1 in lipid nanodiscs
EMPIAR dataset·2023Open Access
Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs bound to AMP-PNP (200 kV)
EMPIAR dataset·2022Open Access
Cryo-EM structure of the mutant solitary ECF module 2EQ in MSP2N2 lipid nanodiscs in the ATPase closed and ATP-bound conformation (300 kV)
EMPIAR dataset·2022Open Access
Cryo-EM structure of the folate-specific ECF transporter complex in MSP2N2 lipid nanodiscs bound to ATP and ADP (200 kV)
EMPIAR dataset·2022Open Access
Cryo-EM structure of the wild-type solitary ECF module in DDM micelles in the ATPase open and nucleotide-free conformation (200 kV)
EMPIAR dataset·2022Open Access
Cryo-EM structure of the wild-type solitary ECF module in MSP2N2 lipid nanodiscs in the ATPase open and nucleotide-free conformation (200 kV)
EMPIAR dataset·2022Open Access
Anionic lipids unlock the gates of select ion channels in the pacemaker family
Nature Structural & Molecular Biology·2022· 36 citedOpen Access
Inhibited KdpFABC transitions into an E1 off-cycle state
eLife·2022· 21 citedOpen Access
Author response: Inhibited KdpFABC transitions into an E1 off-cycle state
2022Open Access
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Frequent Co-authors

Cristina Paulino(27), Crina M. Nimigean(15), Dirk Jan Slotboom(12), Chancievan Thangaratnarajah(10), Philipp A. M. Schmidpeter(8), Przemysław Nogły(5), Valérie Panneels(5), Cornelius Gati(5), Gebhard F. X. Schertler(5), Alisa A. Garaeva(5), Valeria Kalienkova(5), Maria E. Falzone(4), Byoung‐Cheol Lee(4), Thasin Peyear(4), Linda Sasset(4), Ashleigh M. Raczkowski(4), Edward T. Eng(4), Annarita Di Lorenzo(4), Alessio Accardi(4), Garrett Nelson(4)