David do Carmo Malvar

Universidade Federal Rural do Rio de Janeiro — Brazil

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index637citations31works0.02yr avg
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Research Topics

Natural product bioactivities and synthesis(5), Pain Mechanisms and Treatments(4), Immune Response and Inflammation(4), Ion channel regulation and function(4), Receptor Mechanisms and Signaling(4)

Publications31 total

Perinatal environmental enrichment changes anxiety-like behaviours in mice and produces similar intergenerational benefits in offspring
Behavioural Brain Research·2023· 7 cited
Oral treatments with a flavonoid-enriched fraction from Cecropia hololeuca and with rutin reduce articular pain and inflammation in murine zymosan-induced arthritis
Journal of Ethnopharmacology·2020· 25 cited
L-arginine supplementation and thromboxane synthase inhibition increases cerebral blood flow in experimental cerebral malaria
Scientific Reports·2019· 21 citedOpen Access
Regulation of murine arthritis by systemic, spinal, and intra-articular adrenoceptors
Pharmacological Reports·2019· 3 cited
Estradiol replacement therapy regulates innate immune response in ovariectomized arthritic mice
International Immunopharmacology·2019· 34 cited
Alterations in hypothalamic synaptophysin and death markers may be associated with vasopressin impairment in sepsis survivor rats
Journal of Neuroendocrinology·2018· 16 cited
The folk medicine as tool for discovery of new anti-inflammatory drugs: the example of<i>Spermacoce verticillata</i>
Acta Horticulturae·2018· 3 cited
Spinal GABA-B receptor modulates neutrophil recruitment to the knee joint in zymosan-induced arthritis
Naunyn-Schmiedeberg s Archives of Pharmacology·2016· 15 citedOpen Access
Cytokines, but not corticotropin-releasing factor and endothelin-1, participate centrally in the febrile response in zymosan-induced arthritis in rats
Brain Research·2015· 5 citedOpen Access
Dipyrone metabolite 4‐<scp>MAA</scp> induces hypothermia and inhibits <scp>PGE</scp><sub>2</sub>‐dependent and ‐independent fever while 4‐<scp>AA</scp> only blocks <scp>PGE</scp><sub>2</sub>‐dependent fever
British Journal of Pharmacology·2014· 28 citedOpen Access
Mechanisms Underlying the Antinociceptive, Antiedematogenic, and Anti‐Inflammatory Activity of the Main Flavonoid from<i>Kalanchoe pinnata</i>
Evidence-based Complementary and Alternative Medicine·2014· 52 citedOpen Access
Antinociceptive, anti-inflammatory and antipyretic effects of 1.5-diphenyl-1H-Pyrazole-3-carbohydrazide, a new heterocyclic pyrazole derivative
Life Sciences·2013· 85 citedOpen Access
Synthesis of Dipyrone Metabolites and Evaluation of their Antipyretic Effect
Proceedings of the 15th Brazilian Meeting on Organic Synthesis Proceedings·2013Open Access
Simultaneous Determination of Dipyrone Metabolites in Rat Hypothalamus, Cerebrospinal Fluid and Plasma Samples by LC–MS/MS
Bioanalysis·2013· 8 cited
Antinociceptive effect of dipyrone and its metabolites on hyperalgesia induced by carragenan and prostaglandin E'IND.2'
Program·2013
Flavonoids in the therapy and prophylaxis of flu: a patent review
Expert Opinion on Therapeutic Patents·2012· 10 cited
Involvement of PGE<sub>2</sub>and RANTES in<i>Staphylococcus aureus-</i>induced fever in rats
Journal of Applied Physiology·2012· 6 cited
Erratum to: Febrile response induced by cecal ligation and puncture (CLP) in rats: involvement of prostaglandin E2 and cytokines
Medical Microbiology and Immunology·2012Open Access
DETERMINATION OF DICLOFENAC SODIUM IN RABBIT PLASMA BY HPLC/UV: EVALUATION AND CHARACTERIZATION OF ITS CRYSTALLINE FORMS, ANHYDROUS AND HYDRATE, ON THE ANTIPYRETIC EFFECT
Journal of Liquid Chromatography & Related Technologies·2012· 1 citedOpen Access
Anti-inflammatory and opioid-like activities in methanol extract of Mikania lindleyana, sucuriju
Revista Brasileira de Farmacognosia·2011· 7 citedOpen Access
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Frequent Co-authors

Glória Emília Petto de Souza(14), Alexandre Kanashiro(11), Frederico Argollo Vanderlinde(9), Denis de Melo Soares(8), Maria José Figueiredo(8), Renes R. Machado(7), Fernando Armani Aguiar(6), Giuliano C. Clososki(6), Élson Alves Costa(5), Sônia Soares Costa(5), Fernando Q. Cunha(5), Fábio Fagundes da Rocha(4), Raquel Teixeira Ferreira(4), Andréa C. Pessini(4), M. C. C. Melo(4), Iziara Ferreira Florentino(3), Giles A. Rae(3), Wellington da Silva Côrtes(3), André S. Mecawi(3), Artur de L.L. Vaz(3)