Jay H. Thakar

Indiana University School of Medicine

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index1.0kcitations35works0.02yr avg
OpenAlex↗Google Scholar↗Lab page↗

Accepting Students?

No reports yet. Know if this professor is taking students?

Research Topics

Mitochondrial Function and Pathology(11), Muscle Physiology and Disorders(7), Parkinson's Disease Mechanisms and Treatments(6), Genetic Neurodegenerative Diseases(5), Bipolar Disorder and Treatment(4)

Publications35 total

Pyruvate Dehydrogenase Complex Activity Controls Metabolic and Malignant Phenotype in Cancer Cells
Journal of Biological Chemistry·2008· 381 citedOpen Access
Increased lactate levels and reduced pH in postmortem brains of schizophrenics: Medication confounds
Journal of Neuroscience Methods·2007· 93 citedOpen Access
Erythrocyte Membrane ATP Binding Cassette (ABC) Proteins: MRP1 and CFTR as Well as CD39 (Ecto-apyrase) Involved in RBC ATP Transport and Elevated Blood Plasma ATP of Cystic Fibrosis
Blood Cells Molecules and Diseases·2001· 58 cited
Reversal of impaired oxidative phosphorylation and calcium overloading in the skeletal muscle mitochondria of CHF-146 dystrophic hamsters
Molecular and Chemical Neuropathology·1998· 13 cited
Characterization of the intracellular distribution and binding in human adenocarcinoma cells of N-(4-azidophenyl-sulfonyl)-N′-(4-chlorophenyl)urea (LY219703), a photoaffinity analogue of the antitumor diarylsulfonylurea sulofenur
Biochemical Pharmacology·1995· 10 cited
Cross-resistance to antitumor diarylsulfonylureas and collateral sensitivity to mitochondrial toxins in a human cell line selected for resistance to the antitumor agent N-(5-indanylsulfonyl)-N'-(4-chlorophenyl)urea.
Molecular Pharmacology·1994· 16 cited
Reversal of impaired oxidative phosphorylation and calcium overloading in the in vitro cardiac mitochondria of CHF-146 dystrophic hamsters with hereditary muscular dystrophy
Journal of the Neurological Sciences·1993· 17 cited
Proliferation-dependent and -independent cytotoxicity by antitumor diarylsulfonylureas
Biochemical Pharmacology·1993· 22 cited
Effect of antitumor diarylsulfonylureas on in vivo and in vitro mitochondrial structure and functions.
PubMed·1991· 26 cited
Isolation of skeletal muscle mitochondria from hamsters using an lonic medium containing ethylenediarninetetraacetic acid and nagarse
Analytical Biochemistry·1991· 97 cited
Influence of Extracellular pH on the Accumulation and Cytotoxicity of N-(4-Methylphenylsulfonyl)-N′-(4-chlorophenyl)urea in Human Cell Lines
Cancer Communications·1991· 6 citedOpen Access
Diarylsulfonylureas : new anticancer agents with novel activities, toxicities and mechanism of action
1991· 4 cited
Pathogenetic Roles of Intracellular Calcium and Magnesium in Membrane-Mediated Progressive Muscle Degeneration in Duchenne Muscular Dystrophy
1989· 8 cited
Effects of 6-hydroxydopamine on oxidative phosphorylation of mitochondria from rat striatum, cortex, and liver
Canadian Journal of Physiology and Pharmacology·1988· 15 cited
Effects of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine (MPTP), cyperquat (MPP+) and paraquat on isolated mitochondria from rat striatum, cortex and liver
Life Sciences·1988· 33 cited
Dopamine receptors in Parkinson's disease
Progress in Neuro-Psychopharmacology and Biological Psychiatry·1988· 21 cited
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), its metabolite cyperquat (MPP+) and energy transduction in mitochondria from rat striatum and liver
Progress in Neuro-Psychopharmacology and Biological Psychiatry·1988· 3 cited
Prevention of progression of Parkinson's disease with antioxidative therapy
Progress in Neuro-Psychopharmacology and Biological Psychiatry·1988· 14 cited
Antioxidant Therapy in Parkinson's Disease
Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques·1987· 31 citedOpen Access
Cyperquat (MPP+), but not MPTP or Paraquat Inhibits Oxygen Consumption in Mitochondria from Rat Striatum
Advances in behavioral biology·1987· 1 cited
page 1 of 2Next →

Frequent Co-authors

Mohamed N. Hassan(7), K. P. Strickland(5), Janek Sosinski(5), Peter J. Houghton(5), Syamal K. Bhattacharya(4), Patti L. Johnson(4), Brent Waters(4), J. David Grimes(3), Y.D. Lapierre(3), Nader D. Halim(2), Ajay Verma(2), Anna Hudson(2), Klaus Wrogemann(2), M. C. Blanchaer(2), Cheryl Chapin(2), Glen S. Germain(2), Franklin C. Harwood(2), D. H. Percy(2), Thomas McFate(1), Ahmed Mohyeldin(1)