Deena Iskander

Imperial College Healthcare NHS Trust — United Kingdom

Biochemistry, Genetics and Molecular Biology · Life Sciences

12h-index819citations52works4.72yr avg
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Research Topics

RNA modifications and cancer(16), Cancer-related gene regulation(10), Acute Myeloid Leukemia Research(9), Hemoglobinopathies and Related Disorders(7), Erythrocyte Function and Pathophysiology(7)

Publications52 total

The international diamond blackfan anemia syndrome cancer consortium: Preliminary results
Blood·2025
Increased prevalence and severity of cardiac iron overload in transfusion dependent diamond-blackfan anemia syndrome caused by small versus large ribosomal subunit mutations
Blood·2025Open Access
RPS19 and RPL5 Haploinsufficient Models Reveal Divergent Ribosomal Subunit Controls of Fetal Hematopoiesis
2025Open Access
Imbalanced TGFβ signalling and autophagy drive erythroid priming of hematopoietic stem cells in β-thalassemia
Nature Communications·2025· 1 citedOpen Access
The role of glucocorticoids in erythropoiesis
Frontiers in Hematology·2025· 4 citedOpen Access
Spatial Transcriptomics Identifies Aberrant Communication between Dendritic Cells and Leukemia Stem Cells As a Therapeutically Targetable Axis in Juvenile Myelomonocytic Leukemia
Blood·2024· 1 cited
Multimodal Single Cell Analysis Reveals Hematopoietic Changes across the Human Lifespan
Blood·2024
The Fetal Specific Gene <i>LIN28B</i> Is Essential for Human Fetal B-Lymphopoiesis and Initiation of <i>KMT2A-AFF1+</i> Infant Acute Lymphoblastic Leukemia
Blood·2024· 1 citedOpen Access
The fetal specific gene <i>LIN28B</i> is essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia
2024Open Access
Harnessing Single-Cell Technologies in the Search for New Therapies for Diamond–Blackfan Anemia Syndrome
Experimental Hematology·2024· 5 citedOpen Access
Diagnosis, treatment, and surveillance of Diamond-Blackfan anaemia syndrome: international consensus statement
The Lancet Haematology·2024· 44 citedOpen Access
The molecular basis of bone marrow failure syndromes and red cell enzymopathies
2024Open Access
P332: LIN28B: AN IMPORTANT ONCO-FETAL GENE IN INFANT ACUTE LYMPHOBLASTIC LEUKAEMIA
HemaSphere·2023Open Access
Diamond-Blackfan anemia in adults: In pursuit of a common approach for a rare disease
Blood Reviews·2023· 12 cited
3159 – A SINGLE-CELL PROTEIN-TRANSCRIPTOME ATLAS OF HAEMATOPOIESIS ACROSS THE HUMAN LIFESPAN
Experimental Hematology·2023Open Access
Two’s company but three’s a blast!
Blood·2022· 1 citedOpen Access
Turning up the HEAT(R3) in Diamond-Blackfan anemia
Blood·2022Open Access
3166 – A PROTEIN‐TRANSCRIPTOME ATLAS OF HAEMATOPOIESIS ACROSS THE HUMAN LIFESPAN
Experimental Hematology·2022
1011 – INVESTIGATION OF HUMAN BONE MARROW PROGENITORS ELUCIDATES CELLULAR AND MOLECULAR MECHANISMS OF ERYTHROID FAILURE IN DIAMOND-BLACKFAN ANEMIA
Experimental Hematology·2022
Single-cell profiling of human bone marrow progenitors reveals mechanisms of failing erythropoiesis in Diamond-Blackfan anemia
Science Translational Medicine·2021· 61 citedOpen Access
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Frequent Co-authors

Irene Roberts(31), Anastasios Karadimitris(26), Anindita Roy(19), Adam J. Mead(16), Josu de la Fuente(15), Bethan Psaila(14), Valentina S. Caputo(12), Supat Thongjuea(10), Aristeidis Chaidos(9), Guanlin Wang(8), Elisabeth F. Heuston(8), David M. Bodine(8), Natalina Elliott(8), Yvonne Harrington(8), Alba Rodríguez-Meira(7), Neil Ashley(7), Sorcha O’Byrne(7), Kanagaraju Ponnusamy(7), Nikolaos Trasanidis(7), Gemma Buck(6)