Shu‐ou Shan

California Institute of Technology — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

47h-index6.5kcitations161works2.82yr avg
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Research Topics

RNA and protein synthesis mechanisms(83), Bacterial Genetics and Biotechnology(61), Protein Structure and Dynamics(26), Bacteriophages and microbial interactions(22), Endoplasmic Reticulum Stress and Disease(22)

Publications161 total

Comprehensive pan-cancer analysis of TRAP1 and its experimental validation in hepatocellular carcinoma
Discover Oncology·2025Open Access
Mechanism of cotranslational modification of histones H2A and H4 by MetAP1 and NatD
Science Advances·2025· 1 citedOpen Access
HYPK promotes N-terminal protein acetylation through rapid ribosome exchange of NatA
Molecular Cell·2025Open Access
Unveiling macrophage-fibroblast-driven inflammatory networks mediated pan-cancer immune features by integrated single-cell and bulk RNA sequencing
International Journal of Surgery·2025Open Access
Temporal Regulation of Signal Recognition Particle During Translation
Journal of Molecular Biology·2025Open Access
Comprehensive pan-cancer analysis and experimental validation of TRAP1 as a possible medicinal target
2025Open Access
Principles of cotranslational mitochondrial protein import
Cell·2025· 12 citedOpen Access
<scp>HYPK</scp> ‐Related Neurodevelopmental Syndrome: Case Report of Intellectual Disability, Developmental Delay, and Dysmorphic Features
Clinical Genetics·2025Open Access
NAC promotes co-translational protein folding at the ribosomal tunnel exit
2025· 1 citedOpen Access
A molecular switch in NAC prevents mitochondrial protein mistargeting by SRP
2025Open Access
Author response for "HYPK-Related Neurodevelopmental Syndrome: Case Report of Intellectual Disability, Developmental Delay, and Dysmorphic Features"
2025
Author response for "HYPK-Related Neurodevelopmental Syndrome: Case Report of Intellectual Disability, Developmental Delay, and Dysmorphic Features"
2025
FPFS-YOLO: An Insulator Defect Detection Model Integrating FasterNet and an Attention Mechanism
Sensors·2025· 4 citedOpen Access
Mechanism of cotranslational protein N-myristoylation in human cells
Molecular Cell·2025· 6 citedOpen Access
Switchable client specificity in a dual functional chaperone coordinates light-harvesting complex biogenesis
Science Advances·2025Open Access
Abstract 1634 A ribosome exchange factor for cotranslational N-terminal protein acetylation
Journal of Biological Chemistry·2025Open Access
Mechanistic Insights into Protein Biogenesis and Maturation on the Ribosome
Journal of Molecular Biology·2025· 4 citedOpen Access
BPS2025 - Principle of cotranslational protein targeting to mitochondria
Biophysical Journal·2025
Temporal Regulation of Signal Recognition Particle During Translation
SSRN Electronic Journal·2025Open Access
Channel Gating in a Post-Translational Protein Translocase
Biochemistry·2024
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Frequent Co-authors

Daniel Herschlag(10), Peter Walter(8), Kuang Shen(7), Nenad Ban(7), Michael E. Rome(5), David Akopian(4), Xin Zhang(4), Sowmya Chandrasekar(4), Joseph A. Piccirilli(3), Hyun-Ju Cho(3), Ahmad Jomaa(3), Meera Rao(3), Daniel Boehringer(3), Pascal F. Egea(2), R. M. Stroud(2), Nathan W. Pierce(2), Michael J. Sweredoski(2), R. L. Graham(2), Sonja Hess(2), Raymond J. Deshaies(2)