Robert A. Bonomo

Veterans Health Administration — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

114h-index59.9kcitations1.1kworks3.62yr avg
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Research Topics

Antibiotic Resistance in Bacteria(797), Antibiotics Pharmacokinetics and Efficacy(303), Antibiotic Use and Resistance(159), Vibrio bacteria research studies(139), Bacterial Identification and Susceptibility Testing(115)

Publications1.1k total

A mechanism-based pharmacokinetic/pharmacodynamic analysis of polymyxin B-based combination therapy against carbapenem-resistant <i>Klebsiella pneumoniae</i> isolates with diverse phenotypic and genotypic resistance mechanisms
Antimicrobial Agents and Chemotherapy·2025· 1 citedOpen Access
Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase
2025Open Access
Author response: Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase
2025Open Access
Response to “The promise and pitfalls: interpreting dual β-lactam success in <i>Mycobacterium abscessus</i> with caution”
ASM Case Reports·2025Open Access
Zinc starvation uncovers bacterial host-specific proteases that shape NDM adaptability in <i>Acinetobacter baumannii</i>
mBio·2025Open Access
Impact of <i>Pseudomonas aeruginosa</i> biofilm exopolysaccharide composition on bacteriophage and bacteriophage-antibiotic combination activity
Antimicrobial Agents and Chemotherapy·2025Open Access
Structural and Kinetic Basis for the Rational Design of Next-Generation β-Lactamase Inhibitors
2025
Ampicillin/Sulbactam in Combination with Ceftazidime/Avibactam Against Metallo-β-Lactamase-Producing Carbapenem-Resistant <i>Acinetobacter baumannii</i> : A Genomics-Informed Mechanism-based model
The Journal of Infectious Diseases·2025Open Access
Global health at crossroads: uniting together to overcome challenges, restore trust and advance priorities for a sustainable future
World Journal of Emergency Surgery·2025· 1 citedOpen Access
Binding and Unbinding Pathways of a β-Lactamase Inhibitor
2025
Let’s Dance: How Protein Dynamics Drive β-Lactamase Evolution and Antibiotic Resistance?
Biochemistry·2025
76 Targeting Mycobacterium abscessus: dual mechanisms and enhanced killing by optimized β-lactam/β-lactamase inhibitor combinations
Journal of Cystic Fibrosis·2025
A-321 Performance evaluation of a rapid, universal and automation amenable sepsis diagnostic workflow that identifies pathogens and determines their antimicrobial resistance directly from whole blood
Clinical Chemistry·2025Open Access
The Role of β-Lactam Antibiotics in Treating <i>Mycobacterium abscessus</i> : From Laboratory Insights to Clinical Applications and the Case for Clinical Trials
Clinical Infectious Diseases·2025· 3 citedOpen Access
Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase
eLife·2025Open Access
Ω-Loop mutations control dynamics of the active site by modulating the hydrogen-bonding network in PDC-3 β-lactamase
2025Open Access
Evolution under vancomycin selection drives divergent collateral sensitivity patterns in <i>Staphylococcus aureus</i>
Proceedings of the National Academy of Sciences·2025Open Access
Genomic insights of two Acinetobacter non-baumannii strains with uncommon mechanisms of resistance leading to cefiderocol resistance
Infection Genetics and Evolution·2025· 1 citedOpen Access
Mechanistic basis for inhibition of the extended‐spectrum β‐lactamase <scp>GES</scp> ‐1 by enmetazobactam and tazobactam
FEBS Letters·2025Open Access
<i>Burkholderia pseudomallei</i> PenI β-lactamase and variants are potently inhibited by taniborbactam
Antimicrobial Agents and Chemotherapy·2025Open Access
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Frequent Co-authors

David L. Paterson(17), David van Duin(14), Yohei Doi(11), Andrea M. Hujer(9), Kristine M. Hujer(8), Liang Chen(8), Pranita D. Tamma(7), Keith S. Kaye(7), Vance G. Fowler(7), Barry N. Kreiswirth(7), Michael R. Jacobs(7), Federico Pérez(6), Eric Cober(6), Scott Evans(6), Michael J. Satlin(6), Henry F. Chambers(6), Louis B. Rice(5), Samuel L Aitken(5), Amy J. Mathers(5), Cornelius J. Clancy(5)