Torsten Hartwig

CRUK Lung Cancer Centre of Excellence — United Kingdom

Immunology and Microbiology · Life Sciences

10h-index1.3kcitations13works0.02yr avg
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Research Topics

interferon and immune responses(6), Ubiquitin and proteasome pathways(5), Cell death mechanisms and regulation(4), Cancer-related Molecular Pathways(3), Immune cells in cancer(2)

Publications13 total

TRAIL-receptor 2—a novel negative regulator of p53
Cell Death and Disease·2021· 19 citedOpen Access
LUBAC prevents lethal dermatitis by inhibiting cell death induced by TNF, TRAIL and CD95L
Nature Communications·2018· 101 citedOpen Access
Abstract B13: The impact of combined CDK9 inhibition and TRAIL treatment on NSCLC
Clinical Cancer Research·2018· 1 cited
Abstract B18: Characterization and therapeutic harnessing of TRAIL’s pro-tumorigenic and pro-apoptotic functions in cancer
Clinical Cancer Research·2018
LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis
Nature·2018· 207 cited
Molecular and functional determinants of the TRAIL-induced tumour-supportive secretome
UCL Discovery (University College London)·2018
Paving TRAIL’s Path with Ubiquitin
Trends in Biochemical Sciences·2017· 44 cited
The linear ubiquitin chain assembly complex regulates <scp>TRAIL</scp> ‐induced gene activation and cell death
The EMBO Journal·2017· 106 citedOpen Access
The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2
Molecular Cell·2017· 238 citedOpen Access
LUBAC deficiency perturbs TLR3 signaling to cause immunodeficiency and autoinflammation
The Journal of Experimental Medicine·2016· 89 citedOpen Access
LUBAC-Recruited CYLD and A20 Regulate Gene Activation and Cell Death by Exerting Opposing Effects on Linear Ubiquitin in Signaling Complexes
Cell Reports·2015· 284 citedOpen Access
Cancer Cell-Autonomous TRAIL-R Signaling Promotes KRAS-Driven Cancer Progression, Invasion, and Metastasis
Cancer Cell·2015· 190 citedOpen Access
The Kv1.2 potassium channel: The position of an N-glycan on the extracellular linkers affects its protein expression and function
Brain Research·2008· 17 cited

Frequent Co-authors

Henning Walczak(11), Lucia Taraborrelli(7), Peter Dráber(6), Antonella Montinaro(6), Silvia von Karstedt(6), Élodie Lafont(5), Sebastian Kupka(4), Silvia Šurinová(4), Eva Rieser(4), Mona El‐Bahrawy(4), Johannes Lemke(4), Nieves Peltzer(3), Maurice Darding(3), Matthias Reichert(2), Helena Draberova(2), Diego de Miguel(2), Tobias L. Haas(2), Yutaka Shimizu(2), Aida Sarr(2), John Bertin(2)