Holly Van Remmen

Oklahoma Medical Research Foundation — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

76h-index27.0kcitations308works8.92yr avg
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Research Topics

Mitochondrial Function and Pathology(101), Muscle Physiology and Disorders(94), Adipose Tissue and Metabolism(68), Genetics, Aging, and Longevity in Model Organisms(39), Exercise and Physiological Responses(36)

Publications306 total

Mitochondrial oxidative stress in skeletal muscle alters metabolic signaling responses to acute muscle contraction
SSRN Electronic Journal·2026Open Access
Age-related decline of chaperone-mediated autophagy in skeletal muscle leads to progressive myopathy
Nature Metabolism·2025· 3 citedOpen Access
Allele-specific correction of ATAD3A pathogenic variants via template-free CRISPR-Cas9 editing and gene conversion
2025Open Access
Mitochondrial Ca<sup>2+</sup> uniporter haploinsufficiency leads to sexually dimorphic redox imbalance and metabolic remodelling in the mouse brain
The Journal of Physiology·2025· 1 cited
Leukocyte-type 12/15-lipoxygenase is essential for timely inflammation-resolution and effective tissue regeneration following skeletal muscle injury
Molecular Metabolism·2025· 3 citedOpen Access
Leukocyte-type 12/15-lipoxygenase is essential for timely inflammation-resolution and effective tissue regeneration following skeletal muscle injury
2025· 2 citedOpen Access
Endothelial IGF- 1R deficiency disrupts microvascular homeostasis, impairing skeletal muscle perfusion and endurance: implications for age-related sarcopenia
GeroScience·2025· 3 citedOpen Access
Mitochondrial dysfunction and fatigue in Sjögren’s disease
RMD Open·2025· 2 citedOpen Access
Pharmacological reduction of lipid hydroperoxides as a potential modulator of sarcopenia
The Journal of Physiology·2025· 2 citedOpen Access
Reactive oxygen species in the pathogenesis of sarcopenia
Free Radical Biology and Medicine·2024· 33 citedOpen Access
The nitrone compound OKN-007 delays motor neuron loss and disease progression in the G93A mouse model of amyotrophic lateral sclerosis
Frontiers in Neuroscience·2024Open Access
Detection of iPLA2 as a novel intracellular Ca2+ regulator in triggering muscle weakness during denervation
Free Radical Biology and Medicine·2024
Glutathione Peroxidase 4 Overexpression Alters Bone Remodeling in response to Injury and Overloading
Free Radical Biology and Medicine·2024
Gpx4 Regulates Invariant NKT Cell Homeostasis and Function by Preventing Lipid Peroxidation and Ferroptosis
The Journal of Immunology·2024· 13 citedOpen Access
A reciprocal relationship between mitochondria and lipid peroxidation determines the chondrocyte intracellular redox environment
Redox Biology·2024· 10 citedOpen Access
Mitochondrial Dysfunction and Fatigue in Sjögren’s Disease
2024· 1 citedOpen Access
Transcriptomic signatures of time-restricted feeding (TRF) in cerebrovascular aging and cognitive health
Vascular Pharmacology·2024
Time-restricted feeding improves aortic endothelial relaxation by enhancing mitochondrial function and attenuating oxidative stress in aged mice
Redox Biology·2024· 28 citedOpen Access
Gpx4 regulates iNKT cell homeostasis and function by preventing ferroptosis and lipid peroxidation
The Journal of Immunology·2024Open Access
Neuroprotective treatment with the nitrone compound OKN-007 mitigates age-related muscle weakness in aging mice
GeroScience·2024· 3 citedOpen Access
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Frequent Co-authors

Arlan Richardson(23), Florian L. Müller(9), Charles J. Epstein(9), Wenbo Qi(9), Yuhong Liu(7), Yuji Ikeno(7), Youngmok C. Jang(6), Qitao Ran(6), Arlan Richardson(5), Adam B. Salmon(5), Michael S. Lustgarten(4), Hong Yang(4), Ting‐Ting Huang(4), L. Jackson Roberts(4), Ting Huang(4), Viviana Pérez(4), Hanyu Liang(4), Randy Strong(3), Alex Bokov(3), Asish R. Chaudhuri(3)