Tsuyoshi Shimoboji

Asahi Kasei (Japan) — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index2.1kcitations23works1.82yr avg
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Research Topics

Hydrogels: synthesis, properties, applications(5), biodegradable polymer synthesis and properties(5), Advanced Polymer Synthesis and Characterization(4), RNA Interference and Gene Delivery(4), Proteoglycans and glycosaminoglycans research(4)

Publications23 total

A long-term antigen-spreading by novel cancer vaccine with hyaluronic acid nanogel accelerate the anti-neoplastic efficacy of cytotoxicity of infused TCR-T cells and altered neplastic microenvironment
Blood·2025
Abstract 6745: Crafting hyaluronic acid-based nanoparticles for enhanced LN targeting as a potent priming tool in immunotherapy
Cancer Research·2024
Abstract 4091: A novel cancer vaccine based on hyaluronic acid nanogel combined with adoptive T cell therapy induces complete regression of established tumors and long-lasting memory CD8+ T cells
Cancer Research·2024
Variable swelling behavior of and drug encapsulation in a maleimide-modified hyaluronic acid nanogel-based hydrogel
Polymer Journal·2024· 7 citedOpen Access
Self-assembled nanogels based on hyaluronic acid for antibody protection from heat denaturation
Biochemical Engineering Journal·2023· 7 cited
359 Hyaluronic acid nanogel based cancer vaccine, in combination with adoptive T cell therapy totally suppresses ICI resistant-tumors
Regular and Young Investigator Award Abstracts·2022Open Access
Injectable Hydrogel for Sustained Protein Release by Salt‐Induced Association of Hyaluronic Acid Nanogel
Macromolecular Bioscience·2012· 98 cited
Hybrid hyaluronan hydrogel encapsulating nanogel as a protein nanocarrier: New system for sustained delivery of protein with a chaperone-like function
Journal of Controlled Release·2009· 126 cited
Synthesis and degradation test of hyaluronic acid hydrogels
International Journal of Biological Macromolecules·2006· 117 cited
Selectively crosslinked hyaluronic acid hydrogels for sustained release formulation of erythropoietin
Journal of Biomedical Materials Research Part A·2006· 58 cited
Intelligent Biohybrid Materials for Therapeutic and Imaging Agent Delivery
Proceedings of the IEEE·2005· 30 cited
Temperature-Induced Switching of Enzyme Activity with Smart Polymer−Enzyme Conjugates
Bioconjugate Chemistry·2003· 149 cited
Smart bioconjugates
2003· 1 cited
Photoresponsive polymer–enzyme switches
Proceedings of the National Academy of Sciences·2002· 316 citedOpen Access
Bioinspired Engineering of Intelligent Drug Delivery Systems and Protein– Polymer Conjugates
2002· 2 cited
Photoswitching of Ligand Association with a Photoresponsive Polymer−Protein Conjugate
Bioconjugate Chemistry·2002· 116 cited
Mechanistic Investigation of Smart Polymer−Protein Conjugates
Bioconjugate Chemistry·2001· 44 cited
Photo-switching of protein activities by conjugation of photo-responsive polymers to proteins
ResearchWorks at the University of Washington (University of Washington)·2001Open Access
Really smart bioconjugates of smart polymers and receptor proteins
Journal of Biomedical Materials Research·2000· 8 cited
Really smart bioconjugates of smart polymers and receptor proteins
Journal of Biomedical Materials Research·2000· 336 cited
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Frequent Co-authors

Patrick S. Stayton(12), Allan S. Hoffman(9), Zhongli Ding(6), Kohei Yabuuchi(6), Toru Katsumata(6), Chantal A. Lackey(5), Niren Murthy(5), Ashutosh Chilkoti(4), J. Milton Harris(4), Volga Bulmuş(4), Oliver W. Press(4), Shogo Aso(4), Fumiyasu Momose(4), Cynthia J. Long(3), Guohua Chen(3), Jingping Chen(3), Morikazu Miura(3), Nobuo Monji(3), Katsuhiko Nakamae(3), Kazunari Akiyoshi(3)