Michael Rusch

St. Jude Children's Research Hospital — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

54h-index21.1kcitations248works7.12yr avg
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Research Topics

Cancer Genomics and Diagnostics(102), Acute Lymphoblastic Leukemia research(63), Genomics and Rare Diseases(51), Acute Myeloid Leukemia Research(33), Sarcoma Diagnosis and Treatment(23)

Publications248 total

Fast and sensitive detection of targeted gene fusions using frequency minimizers and fuzzy pattern matching with Fuzzion2
Cell Reports Methods·2025Open Access
INTEGRATION OF A BONE MARROW FAILURE GERMLINE PANEL INTO THE COMPREHENSIVE CLINICAL GENOMICS PIPELINE AT ST. JUDE CHILDREN’S RESEARCH HOSPITAL: INSIGHTS FROM 22 MONTHS’ EXPERIENCE
EJC Paediatric Oncology·2025Open Access
Clinical experience of using integrated whole genome and transcriptome sequencing as a framework for pediatric and adolescent acute myeloid leukemia diagnosis and risk assessment
Leukemia·2025· 2 citedOpen Access
scMINER: a mutual information-based framework for clustering and hidden driver inference from single-cell transcriptomics data
Nature Communications·2025· 6 citedOpen Access
Abstract 712: The genomic landscape of subsequent breast, meningioma, and thyroid neoplasms after treatment for childhood cancer: a report from the Childhood Cancer Survivor Study
Cancer Research·2025
Abstract 7178: Advancing WGS and WTS diagnostic testing for pediatric leukemia: fast-tracking CNV, ploidy, and fusion oncogene detection in 5 days
Cancer Research·2025
Abstract 1089: Developing subtype-specific pediatric cancer molecular targets by aggregating diverse genomic data resources to the pediatric cancer (PeCan) knowledge base portal
Cancer Research·2025
Integrated Whole Genome and Transcriptome Sequencing as a Framework for Pediatric and Adolescent AML Diagnosis and Risk Assessment
2025Open Access
P328: Integration of a bone marrow failure germline panel into the comprehensive clinical genomics pipeline at St. Jude Children’s Research Hospital
Genetics in Medicine Open·2025Open Access
Data from Mutational Landscape and Patterns of Clonal Evolution in Relapsed Pediatric Acute Lymphoblastic Leukemia
2024Open Access
Supplementary Tables from Mutational Landscape and Patterns of Clonal Evolution in Relapsed Pediatric Acute Lymphoblastic Leukemia
2024Open Access
Supplementary Note from Mutational Landscape and Patterns of Clonal Evolution in Relapsed Pediatric Acute Lymphoblastic Leukemia
2024Open Access
Author Correction: Cancer-associated DDX3X mutations drive stress granule assembly and impair global translation
Scientific Reports·2024Open Access
A new genomic framework to categorize pediatric acute myeloid leukemia
Nature Genetics·2024· 92 citedOpen Access
Cancer germline predisposing variants and late mortality from subsequent malignant neoplasms among long-term childhood cancer survivors: a report from the St Jude Lifetime Cohort and the Childhood Cancer Survivor Study
The Lancet Oncology·2023· 17 citedOpen Access
Proposal of a new genomic framework for categorization of pediatric acute myeloid leukemia associated with prognosis
2023· 4 citedOpen Access
NetBID2 provides comprehensive hidden driver analysis
Nature Communications·2023· 27 citedOpen Access
Supplementary Figure from Integrated Genomic Analysis Identifies <i>UBTF</i> Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
2023Open Access
Abstract 3163: Ontology guided navigation of somatic variants, mutational signatures, gene expression and histology images for pediatric cancer
Cancer Research·2023
Supplementary Data from Integrated Genomic Analysis Identifies <i>UBTF</i> Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
2023Open Access
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Frequent Co-authors

Jinghui Zhang(44), John Easton(38), James R. Downing(37), Gang Wu(32), Charles G. Mullighan(24), Michael N. Edmonson(23), Xiang Chen(21), Elaine R. Mardis(21), Richard K. Wilson(20), Sheila Shurtleff(19), Heather L. Mulder(19), Xiaotu Ma(19), David W. Ellison(19), Li Ding(18), Jing Ma(18), Guangchun Song(18), Stanley Pounds(17), Matthew Parker(17), Pankaj Gupta(15), Donald Yergeau(15)