Robert Hyman

Broad Institute — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

49h-index9.3kcitations116works0.02yr avg
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Research Topics

Glycosylation and Glycoproteins Research(48), Monoclonal and Polyclonal Antibodies Research(36), Proteoglycans and glycosaminoglycans research(24), T-cell and B-cell Immunology(20), Cell Adhesion Molecules Research(18)

Publications115 total

Clonal memory of colitis accumulates and promotes tumor growth
2025Open Access
Clonal memory of colitis accumulates and promotes tumor growth
2025Open Access
Time After Time
2009
TSG-6 Modulates the Interaction between Hyaluronan and Cell Surface CD44
Journal of Biological Chemistry·2004· 176 citedOpen Access
Role of the Extracellular and Cytoplasmic Domains of CD44 in the Rolling Interaction of Lymphoid Cells with Hyaluronan under Physiologic Flow
Journal of Biological Chemistry·2003· 42 citedOpen Access
Hyaluronan Binding Properties of a CD44 Chimera Containing the Link Module of TSG-6
Journal of Biological Chemistry·2002· 76 citedOpen Access
Lack of a consistent relationship between demethylation of the CD44 promoter and CD44 expression
Immunogenetics·2002· 8 cited
HYALURONAN BINDING BY CELL SURFACE CD44
Elsevier eBooks·2002· 2 cited
Hyaluronan Binding by Cell Surface CD44
Journal of Biological Chemistry·2000· 377 citedOpen Access
Adhesion of Lymphoid Cells to CD44-Specific Substrata: The Consequences of Attachment Depend on the Ligand
Experimental Cell Research·2000· 23 cited
Kit/stem cell factor receptor-induced activation of phosphatidylinositol 3′-kinase is essential for male fertility
Nature Genetics·2000· 313 cited
The role of the CD44 cytoplasmic and transmembrane domains in constitutive and inducible hyaluronan binding
European Journal of Immunology·2000· 57 citedOpen Access
The role of the CD44 cytoplasmic and transmembrane domains in constitutive and inducible hyaluronan binding
European Journal of Immunology·2000· 2 cited
Site-specific de-N-glycosylation of CD44 can activate hyaluronan binding, and CD44 activation states show distinct threshold densities for hyaluronan binding.
PubMed·1998· 109 cited
The nucleotide sequence of Saccharomyces cerevisiae chromosome V
Nature·1997· 35 cited
CD44 in inflammation and metastasis
Glycoconjugate Journal·1997· 189 cited
Variant cell lines selected for alterations in the function of the hyaluronan receptor CD44 show differences in glycosylation.
The Journal of Experimental Medicine·1995· 194 citedOpen Access
Monoclonal antibodies to CD44 and their influence on hyaluronan recognition.
The Journal of Cell Biology·1995· 129 citedOpen Access
Transmembrane domain of CD44 is required for its detergent insolubility in fibroblasts
Journal of Cell Science·1995· 98 cited
Role of CD44 cytoplasmic domain in hyaluronan binding
European Journal of Immunology·1995· 118 cited
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Frequent Co-authors

Jayne Lesley(27), Ian S. Trowbridge(12), Roberta Schulte(7), Nicole M. English(7), Joseph Trotter(4), Astrid Perschl(4), Bartholomew M. Sefton(3), Qi He(3), Valerie Stallings(3), Tamara R. Hurley(2), P W Kincade(2), István Gál(2), Anthony J. Day(2), Katalin Mikecz(2), Gunther Dennert(2), Andreas Conzelmann(2), Annalisa Spiazzi(2), Claude Bron(2), Kristie Cunningham(2), P W Kincade(1)