Edward Chuang

Rutgers, The State University of New Jersey — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index670citations33works1.42yr avg
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Research Topics

Genetics, Aging, and Longevity in Model Organisms(12), Heat shock proteins research(11), Protein Structure and Dynamics(5), Circadian rhythm and melatonin(4), Reproductive Biology and Fertility(4)

Publications33 total

Design principles to tailor Hsp104 therapeutics
Cell Reports·2024· 2 citedOpen Access
Author response: Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
2024Open Access
Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
eLife·2024· 4 citedOpen Access
Author response: Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
2024Open Access
Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
2024· 1 citedOpen Access
Design principles to tailor Hsp104 therapeutics
2024· 1 citedOpen Access
Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
eLife·2024· 4 citedOpen Access
Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
2024· 2 citedOpen Access
Reviewer #1 (Public Review): Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
2024Open Access
Reviewer #3 (Public Review): Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
2024Open Access
Modulating material properties of cargo protein to probe exopher biology
Biophysical Journal·2024· 1 cited
Defining a small-molecule stimulator of the human Hsp70-disaggregase system with selectivity for DnaJB proteins
2024· 2 citedOpen Access
Mechanical force of uterine occupation enables large vesicle extrusion from proteostressed maternal neurons
2023Open Access
Tuning Hsp104 specificity to selectively detoxify α-synuclein
Molecular Cell·2023· 25 citedOpen Access
Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3
Cell Reports·2022· 24 citedOpen Access
Unique structural features govern the activity of a human mitochondrial AAA+ disaggregase, Skd3
2022· 4 citedOpen Access
Therapeutic genetic variation revealed in diverse Hsp104 homologs
eLife·2020· 27 citedOpen Access
Author response: Therapeutic genetic variation revealed in diverse Hsp104 homologs
2020· 1 citedOpen Access
Mechanistic Insights into Hsp104 Potentiation
UNC Libraries·2020Open Access
Tuning Hsp104 specificity to selectively detoxify α-synuclein
2020· 4 citedOpen Access
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Frequent Co-authors

James Shorter(18), Meredith E. Jackrel(11), Monica Driscoll(10), Guoqiang Wang(9), Ryan Guasp(9), Sangeena Salam(9), Andrés Morera(9), Anna J Smart(9), Sahana Shekhar(9), Ilija Melentijevic(9), David H. Hall(9), Barth D. Grant(9), Alexandrea N. Rizo(7), Daniel R. Southworth(7), Korrie L. Mack(6), Laura M. Castellano(6), David Jiménez(6), E. Friedman(6), Adam L. Yokom(5), Nathan M. Kendsersky(5)