Patrick A. Lewis

University of London — United Kingdom

Medicine · Health Sciences

55h-index21.7kcitations304works1.52yr avg
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Research Topics

Parkinson's Disease Mechanisms and Treatments(113), Neurological diseases and metabolism(38), Alzheimer's disease research and treatments(37), Cellular transport and secretion(29), Lysosomal Storage Disorders Research(24)

Publications291 total

GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis
Science Advances·2025· 3 citedOpen Access
New Frontiers in Animal Prion Diseases
Annual Review of Animal Biosciences·2025
Glutamic Acid at Position 168 Is a Constitutive Activator of Tank Binding Kinase 1 Catalytic Function
NeuroMolecular Medicine·2025Open Access
Young hosts, old challenges: towards the development of a protective pediatric malaria vaccine 2263
The Journal of Immunology·2025Open Access
More than they seem: unveiling diverse roles for γδ T cells in the hepatic immune response to parasitic infection 2244
The Journal of Immunology·2025Open Access
Economic Assessment of Battery Integration in Alaska’s Longline Commercial Fishing Vessels
2025
Bogacki_et_al_TC v1
2025Open Access
Tissue culture protocol for RAW264.7 v1
2025Open Access
Tissue culture protocol for HEK293 cells v1
2025Open Access
In silico phosphoproteomic analysis reveals divergent regulation of Presenilin 1 and Presenilin 2
2025Open Access
Contrasting patterns of interleukin signalling in LRRK2 and idiopathic Parkinson’s
2025Open Access
Glutamic Acid at position 168 is a constitutive activator of Tank Binding Kinase 1 catalytic function
2025Open Access
Glutamic Acid at position 168 is a constitutive activator of Tank Binding Kinase 1 catalytic function
2025Open Access
Loss‐of‐function coding variants in the Ras of complex proteins/ <scp>GTPase</scp> domain of leucine rich repeat kinase 2
Protein Science·2025· 1 citedOpen Access
Evidence suggesting that microglia make amyloid from neuronally expressed APP: a hypothesis
Molecular Neurodegeneration·2025· 1 citedOpen Access
Prevalence and Clinical Characteristics of the <scp> <i>LRRK2</i> </scp> p. <scp>L1795F</scp> Variant in Central Europeans with Early‐Onset and Familial Parkinson's Disease
Movement Disorders Clinical Practice·2025· 1 citedOpen Access
Elimination of intra-hepatocytic malaria parasites is driven by non-canonical autophagy but not nitric oxide production
iScience·2025· 2 citedOpen Access
Differentiation of bone marrow-derived macrophages v1
2025Open Access
GPNMB is a biomarker for lysosomal dysfunction and is secreted via LRRK2-modulated lysosomal exocytosis
2025· 4 citedOpen Access
Loss-of-function coding variants in the Ras of Complex Proteins/GTPase domain of Leucine Rich Repeat Kinase 2
2024Open Access
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Frequent Co-authors

John Hardy(29), Mark Cookson(19), Claudia Manzoni(17), Nicholas Wood(15), Henry Houlden(15), Andrew Singleton(14), Hélène Plun‐Favreau(12), Demis A. Kia(10), Huw R. Morris(10), Daniah Trabzuni(10), Mina Ryten(9), José Brás(8), Alastair J. Noyce(8), Sebastian Guelfi(8), Cornelis Blauwendraat(8), Juan A. Botía(8), Elisa Greggio(7), Rina Bandopadhyay(7), Andrew J. Lees(7), J. Raphael Gibbs(7)