David J. J. de Gorter

University Hospital Münster — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index2.1kcitations34works5.02yr avg
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Research Topics

TGF-β signaling in diseases(9), Bone Metabolism and Diseases(8), Heterotopic Ossification and Related Conditions(6), Bone health and treatments(5), Cell Adhesion Molecules Research(4)

Publications34 total

Hem1 is essential for ruffled border formation in osteoclasts and efficient bone resorption
Scientific Reports·2024· 5 citedOpen Access
Abstract 4999: Preclinical evaluation of MCLA-129, a bispecific antibody targeting EGFR and c-MET on solid tumor cells, in comparison with amivantamab
Cancer Research·2023· 3 cited
Lasp1 regulates adherens junction dynamics and fibroblast transformation in destructive arthritis
Nature Communications·2021· 29 citedOpen Access
Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion
Current Biology·2021· 28 citedOpen Access
Loss of Hem1 disrupts macrophage function and impacts on migration, phagocytosis and integrin-mediated adhesion
2020· 5 citedOpen Access
Importance of osteocyte-mediated regulation of bone remodelling in inflammatory bone disease
Swiss Medical Weekly·2020· 36 citedOpen Access
Signal Transduction Cascades Controlling Osteoblast Differentiation
Primer on the metabolic bone diseases and disorders of mineral metabolism·2018· 35 cited
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes
Nature Cell Biology·2016· 182 citedOpen Access
Towards a cure for Fibrodysplasia ossificans progressiva
Annals of Translational Medicine·2016· 11 citedOpen Access
Ter94/VCP Is a Novel Component Involved in BMP Signaling
PLoS ONE·2014· 11 citedOpen Access
Signal Transduction Cascades Controlling Osteoblast Differentiation
Primer on the metabolic bone diseases and disorders of mineral metabolism·2013· 13 cited
Antisense-Oligonucleotide Mediated Exon Skipping in Activin-Receptor-Like Kinase 2: Inhibiting the Receptor That Is Overactive in Fibrodysplasia Ossificans Progressiva
PLoS ONE·2013· 38 citedOpen Access
Anti-Sclerostin Antibody Inhibits Internalization of Sclerostin and Sclerostin-Mediated Antagonism of Wnt/LRP6 Signaling
PLoS ONE·2013· 60 citedOpen Access
Deregulated Bone Morphogenetic Protein Receptor Signaling Underlies Fibrodysplasia Ossificans Progressiva
Current Pharmaceutical Design·2012· 4 cited
Overactive bone morphogenetic protein signaling in heterotopic ossification and Duchenne muscular dystrophy
Cellular and Molecular Life Sciences·2012· 43 citedOpen Access
Cell‐type specific regulation of myostatin signaling
The FASEB Journal·2011· 67 cited
Reply to the letter to the editor: Could the use of bone morphogenetic proteins in fracture healing do more harm than good to our patients?
International Orthopaedics·2011Open Access
Use and efficacy of bone morphogenetic proteins in fracture healing
International Orthopaedics·2011· 245 citedOpen Access
Dual exon skipping in myostatin and dystrophin for Duchenne muscular dystrophy
BMC Medical Genomics·2011· 48 citedOpen Access
Distinct Modes of Inhibition by Sclerostin on Bone Morphogenetic Protein and Wnt Signaling Pathways
Journal of Biological Chemistry·2010· 174 citedOpen Access
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Frequent Co-authors

Peter ten Dijke(17), Steven T. Pals(5), Marcel Spaargaren(5), Peter A.C. ’t Hoen(5), Willem M.H. Hoogaars(5), Carola Krause(4), Rutger L. van Bezooijen(4), Theresia E. B. Stradal(4), Dwi U. Kemaladewi(4), Annemieke Aartsma‐Rus(4), Clemens W.G.M. Löwik(3), Klemens Rottner(3), Michael Sixt(3), Songting Shi(3), Gonzalo Sánchez‐Duffhues(3), Berno Dankbar(3), Esther A. Beuling(2), Suzanne N. Lissenberg‐Thunnissen(2), Cornelis F.M. Sier(2), Inger B. Schipper(2)