Bernard Lassègue

Emory University — United States

Medicine · Health Sciences

49h-index15.0kcitations116works1.52yr avg
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Research Topics

Nitric Oxide and Endothelin Effects(37), Neutrophil, Myeloperoxidase and Oxidative Mechanisms(35), Cell Adhesion Molecules Research(21), Receptor Mechanisms and Signaling(14), Renin-Angiotensin System Studies(12)

Publications116 total

Poldip2 deficiency attenuates disease severity in a mouse model of COVID-19
2025
Polymerase delta-interacting protein 2 mediates brain vascular permeability by regulating ROS-mediated ZO-1 phosphorylation and localization at the interendothelial border
Cell Communication and Signaling·2025· 3 citedOpen Access
Abstract 12294: Poldip2 Mediates Brain Vascular Permeability by Regulating ZO-1 Phosphorylation and Localization at the Interendothelial Border
Circulation·2023· 1 cited
Myeloid Poldip2 Contributes to the Development of Pulmonary Inflammation by Regulating Neutrophil Adhesion in a Murine Model of Acute Respiratory Distress Syndrome
Journal of the American Heart Association·2022· 5 citedOpen Access
Characterization of Poldip2 knockout mice: Avoiding incorrect gene targeting
PLoS ONE·2021· 5 citedOpen Access
Endothelial Poldip2 regulates sepsis-induced lung injury via Rho pathway activation
Cardiovascular Research·2021· 23 citedOpen Access
Poldip2 controls leukocyte infiltration into the ischemic brain by regulating focal adhesion kinase-mediated VCAM-1 induction
Scientific Reports·2021· 18 citedOpen Access
Characterization of <i>Poldip2</i> knockout mice: avoiding incorrect gene targeting
2021Open Access
<b>β</b>1- and <b>β</b>2-integrins: central players in regulating vascular permeability and leukocyte recruitment during acute inflammation
American Journal of Physiology-Heart and Circulatory Physiology·2020· 31 citedOpen Access
Role of Coronin 1B in PDGF-Induced Migration of Vascular Smooth Muscle Cells
UNC Libraries·2020Open Access
Correction: Platelet-derived growth factor (PDGF) regulates slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells.
Journal of Biological Chemistry·2020· 1 citedOpen Access
Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy
Journal of Neuroinflammation·2019· 104 citedOpen Access
Abstract 593: OPNa and OPNc Contribute to PDGF-Induced Vascular Smooth Muscle Cell Migration and Proliferation
Arteriosclerosis Thrombosis and Vascular Biology·2019
Abstract 103: Vascular Smooth Muscle Cell PGC1alpha Deletion is Atheroprotective <i>in vivo</i>
Arteriosclerosis Thrombosis and Vascular Biology·2019
Polymerase-δ-interacting protein 2 activates the RhoGEF epithelial cell transforming sequence 2 in vascular smooth muscle cells
American Journal of Physiology-Cell Physiology·2019· 14 citedOpen Access
Poldip2 deficiency protects against lung edema and vascular inflammation in a model of acute respiratory distress syndrome
Clinical Science·2019· 25 citedOpen Access
Hernandes et al., 2018.pdf
Figshare·2019Open Access
Discovery and Therapeutic Relevance of Small-Molecule Nox4 Inhibitors
Medicinal chemistry reviews·2018· 1 cited
Abstract 17016: The Role of Polymerase Delta-Interacting Protein 2 in Pulmonary Vascular Inflammation
Circulation·2018
The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo
Laboratory Investigation·2018· 12 citedOpen Access
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Frequent Co-authors

Kathy K. Griendling(45), R. Wayne Alexander(12), Anna Dikalova(9), Alejandra San Martín(8), Dan C. Sorescu(7), J. David Lambeth(6), Alicia N. Lyle(6), Roza E. Clempus(5), Masuko Ushio‐Fukai(5), Katalin Szöcs(5), Lula Hilenski(5), Sergey Dikalov(5), W. Robert Taylor(4), Marjorie Akers(4), Bonnie Seidel-Rogol(4), Lily Pounkova(4), George P. Sorescu(3), Mark T. Quinn(3), Sharon Grant(3), Maria Wendt(3)