Cuige Zhu

Washington University in St. Louis — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index566citations22works0.02yr avg
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Research Topics

Microtubule and mitosis dynamics(4), DNA Repair Mechanisms(3), Phytochemicals and Antioxidant Activities(2), Genomics and Chromatin Dynamics(2), Synthesis and biological activity(2)

Publications22 total

CCL17 Protects Against Viral Myocarditis by Suppressing the Recruitment of Regulatory T Cells
Journal of the American Heart Association·2023· 21 citedOpen Access
Profilin-1 regulates DNA replication forks in a context-dependent fashion by interacting with SNF2H and BOD1L
Nature Communications·2022· 11 citedOpen Access
Ser71 Phosphorylation Inhibits Actin-Binding of Profilin-1 and Its Apoptosis-Sensitizing Activity
Frontiers in Cell and Developmental Biology·2021· 6 citedOpen Access
Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1
Cell Reports·2021· 21 citedOpen Access
1511P A real world study of pyrotinib in patients with HER-2 positive/mutations tumors excluding breast cancer
Annals of Oncology·2020
Phospho-Ser784-VCP Is Required for DNA Damage Response and Is Associated with Poor Prognosis of Chemotherapy-Treated Breast Cancer
Cell Reports·2020· 32 citedOpen Access
TYK2 promotes malignant peripheral nerve sheath tumor progression through inhibition of cell death
Cancer Medicine·2019· 25 citedOpen Access
Abstract 1372: Novel role of the actin-binding factor Profilin-1 in DNA replication
Cancer Research·2018
Synthesis and evaluation of anticancer activity of BOC26P, an ortho-aryl chalcone sodium phosphate as water-soluble prodrugs in vitro and in vivo
Biomedicine & Pharmacotherapy·2017· 16 cited
Identification of 4-arylidene curcumin analogues as novel proteasome inhibitors for potential anticancer agents targeting 19S regulatory particle associated deubiquitinase
Biochemical Pharmacology·2017· 18 cited
Synthesis of the novel PARP-1 inhibitor AG-690/11026014 and its protective effects on angiotensin II-induced mouse cardiac remodeling
Acta Pharmacologica Sinica·2017· 19 citedOpen Access
MC37, a new mono-carbonyl curcumin analog, induces G2/M cell cycle arrest and mitochondria-mediated apoptosis in human colorectal cancer cells
European Journal of Pharmacology·2016· 41 cited
Mitochondria-Targeted Approach: Remarkably Enhanced Cellular Bioactivities of TPP2a as Selective Inhibitor and Probe toward TrxR
ACS Chemical Biology·2015· 39 cited
XYLEM ANATOMY AND HYDRAULIC TRAITS OF TWO CO-OCCURRING RIPARIAN DESERT PLANTS
IAWA Journal - KU Leuven/IAWA Journal·2015· 17 cited
Isolation and cytotoxicity evaluation of taxanes from the barks of Taxus wallichiana var. mairei
Bioorganic & Medicinal Chemistry Letters·2015· 15 cited
Distinct tubulin dynamics in cancer cells explored using a highly tubulin-specific fluorescent probe
Chemical Communications·2015· 5 cited
Short Communication Resistance of Castanea mollissima Shuhe-WYL strain to Dryocosmus kuriphilus and its molecular mechanism
Genetics and Molecular Research·2015· 8 citedOpen Access
Discovery of Potent Cytotoxic Ortho-Aryl Chalcones as New Scaffold Targeting Tubulin and Mitosis with Affinity-Based Fluorescence
Journal of Medicinal Chemistry·2014· 48 cited
A furanyl acryl conjugated coumarin as an efficient inhibitor and a highly selective off–on fluorescent probe for covalent labelling of thioredoxin reductase
Chemical Communications·2014· 40 cited
Synthesis, cytotoxicity of new 4-arylidene curcumin analogues and their multi-functions in inhibition of both NF-κB and Akt signalling
European Journal of Medicinal Chemistry·2012· 31 citedOpen Access
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Frequent Co-authors

Xianzhang Bu(10), Jun Du(8), Xin Yue(7), Gesi Wen(7), Jieya Shao(6), Yinglin Zuo(5), Baoxia Liang(5), Binhua P. Zhou(4), Lei Huang(3), Yu Chen(3), Ruimin Wang(3), Wenjing Qin(3), Faliang Wang(3), Nana Shang(2), Ziyi Liu(2), Yingnan Cao(2), Shuni Wang(2), Weiyan Shao(2), Junmin Quan(2), Jason M. Held(2)