Saku Miyamoto

Takeda (Japan) — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

13h-index1.2kcitations37works4.72yr avg
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Research Topics

Kruppel-like factors research(14), Cancer-related gene regulation(12), Chronic Myeloid Leukemia Treatments(7), Polyamine Metabolism and Applications(4), Amino Acid Enzymes and Metabolism(3)

Publications35 total

Biodistribution of AAV1, AAV5, AAV9, and AAVDJ serotypes after intra-cisterna magna delivery in non-human primates
Molecular Therapy — Methods & Clinical Development·2025· 1 citedOpen Access
The meaning of commerce in the park by the local government
Journal of The Japanese Institute of Landscape Architecture·2024Open Access
Design and synthesis of a novel series of orally active, selective somatostatin receptor 2 agonists for the treatment of type 2 diabetes
Bioorganic & Medicinal Chemistry·2017· 5 citedOpen Access
RNAi Screening Identifies TAK1 as a Potential Target for the Enhanced Efficacy of Topoisomerase Inhibitors
Current Cancer Drug Targets·2011· 36 cited
LACK OF ADDITIONAL PROGNOSTIC BENEFIT BEYOND BLOOD PRESSURE LOWERING EFFECTS IN COMBINATION OF RENIN-ANGIOTENSIN SYSTEM INHIBITOR AND CALCIUM CHANNEL BLOCKER: 2B.04
Journal of Hypertension·2010
Relationship between in vitro phospholipidosis assay using HepG2 cells and 2-week toxicity studies in rats
Toxicology Mechanisms and Methods·2009· 22 cited
Hypothermia enhances heat-shock protein 70 production in ischemic brains
Neuroreport·2009· 30 cited
Promoter Region-Specific Histone Incorporation by the Novel Histone Chaperone ANP32B and DNA-Binding Factor KLF5
Molecular and Cellular Biology·2007· 54 citedOpen Access
KLF5/BTEB2, a Krüppel-like zinc-finger type transcription factor, mediates smooth muscle cell activation as well as cardiovascular remodeling
International Congress Series·2004· 1 cited
POSITIVE AND NEGATIVE REGULATION OF THE CARDIOVASCULAR TRANSCRIPTION FACTOR KLF5 BY THE COACTIVATOR/ACETYLASE P300 AND THE ONCOGENIC REGULATOR/NUCLEOSOME ASSEMBLY FACTOR SET BY INTERACTION AND ACETYLATION—IMPLICATIONS FOR TRANSCRIPTIONAL REGULATION OF GENE EXPRESSION AT THE CHROMATIN LEVEL
Cardiovascular Pathology·2004
OE-102 Positive and negative regulation of the cardiovascular transcription factor KLF5 by p300 and SET through interaction and acetylation(Molecular Biology, Vascular 1 (H) : OE12)(Oral Presentation (English))
Japanese Circulation Journal-english Edition·2004
Positive and Negative Regulation of the Cardiovascular Transcription Factor KLF5 by p300 and the Oncogenic Regulator SET through Interaction and Acetylation on the DNA-Binding Domain
Molecular and Cellular Biology·2003· 124 citedOpen Access
Functional Interaction of the DNA-binding Transcription Factor Sp1 through Its DNA-binding Domain with the Histone Chaperone TAF-I
Journal of Biological Chemistry·2003· 46 citedOpen Access
KLF5 not only Synergistically Activates PDGF-A Gene with NFκ B but also Accelerates SMC Proliferation
Japanese Circulation Journal-english Edition·2003
Proteomic Identification of a Transcriptional Represser of the Transcription Factor KLF5/BTEB2
Japanese Circulation Journal-english Edition·2003
KLF5/BTEB2, a Krüppel-like Transcription Factor, Regulates Smooth Muscle Phenotypic Modulation
Progress in experimental cardiology·2003
Krüppel-like zinc-finger transcription factor KLF5/BTEB2 is a target for angiotensin II signaling and an essential regulator of cardiovascular remodeling
Nature Medicine·2002· 389 cited
Mechanisms of maintenance of endothelial function by the aging-suppressor gene Klotho
Japanese Circulation Journal-english Edition·2002
Transcriptional activation by acetylation of the transcription factor IKLF/BTEB2 by p300
Japanese Circulation Journal-english Edition·2002· 1 cited
Angiotensin II stimulation induces TGF β and its related proteins in cardiac fibroblasts
Japanese Circulation Journal-english Edition·2002
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Frequent Co-authors

Ryozo Nagai(19), Kenichi Aizawa(17), Yasushi Imai(14), Ichiro Manabe(12), Shinsuke Muto(12), Yoshiko Mizuno(12), Toshihiro Amaki(11), Takayuki Shindo(10), Keiko Fukino(10), Koji Maemura(9), Toru Suzuki(9), Toru Suzuki(8), Masahiko Kurabayashi(7), Masami Horikoshi(5), Keiko Kashiwagi(4), Kazuei Igarashi(4), Tomoko Nagino(4), Keiko Kawai‐Kowase(3), Hiroshi Kobayashi(3), Akira Horinouchi(3)