I Flesch

Australian National University — Australia

Medicine · Health Sciences

30h-index3.9kcitations103works2.32yr avg
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Research Topics

Tuberculosis Research and Epidemiology(24), Immunotherapy and Immune Responses(19), Immune Cell Function and Interaction(15), Immunodeficiency and Autoimmune Disorders(13), Immune Response and Inflammation(12)

Publications103 total

A poxvirus model reveals general correlates of antigen presentation and immunogenicity for viral CD8 <sup>+</sup> T cell epitopes
Science Advances·2025Open Access
A quantitative approach to poxvirus infection reveals general correlates of antigen presentation and immunogenicity for viral CD8 <sup>+</sup> T cell epitopes
2024Open Access
DOCK2 Deficiency Causes Defects in Antiviral T-Cell Responses and Impaired Control of Herpes Simplex Virus Infection
The Journal of Infectious Diseases·2024· 7 citedOpen Access
DOCK2-deficiency causes defects in anti-viral T cell responses and poor control of herpes simplex virus infection
2023Open Access
Surprisingly Effective Priming of CD8<sup>+</sup>T Cells by Heat-Inactivated Vaccinia Virus Virions
Journal of Virology·2020· 8 citedOpen Access
Most viral peptides displayed by class I MHC on infected cells are immunogenic
Proceedings of the National Academy of Sciences·2019· 132 citedOpen Access
Extent of Systemic Spread Determines CD8+ T Cell Immunodominance for Laboratory Strains, Smallpox Vaccines, and Zoonotic Isolates of Vaccinia Virus
The Journal of Immunology·2015· 12 citedOpen Access
Delayed control of herpes simplex virus infection and impaired CD4<sup>+</sup> T‐cell migration to the skin in mouse models of DOCK8 deficiency
Immunology and Cell Biology·2015· 16 citedOpen Access
An intact signal peptide on dengue virus E protein enhances immunogenicity for CD8+ T cells and antibody when expressed from modified vaccinia Ankara
Vaccine·2014· 23 cited
Vaccinia virus F5 is required for normal plaque morphology in multiple cell lines but not replication in culture or virulence in mice
Virology·2014· 12 cited
Immunodomination during Peripheral Vaccinia Virus Infection
PLoS Pathogens·2013· 37 citedOpen Access
Kinetics of Antigen Expression and Epitope Presentation during Virus Infection
PLoS Pathogens·2013· 161 citedOpen Access
Linear Fidelity in Quantification of Anti-Viral CD8+ T Cells
PLoS ONE·2012· 22 citedOpen Access
Analyzing CD8 T Cells in Mouse Models of Poxvirus Infection
Methods in molecular biology·2012· 11 cited
Analysis of A47, an Immunoprevalent Protein of Vaccinia Virus, Leads to a Reevaluation of the Total Antiviral CD8<sup>+</sup>T Cell Response
Journal of Virology·2010· 31 citedOpen Access
Altered CD8+ T Cell Immunodominance after Vaccinia Virus Infection and the Naive Repertoire in Inbred and F1 Mice
The Journal of Immunology·2009· 41 citedOpen Access
Vaccinia Virus CD8 <sup>+</sup> T-Cell Dominance Hierarchies Cannot Be Altered by Prior Immunization with Individual Peptides
Journal of Virology·2009· 15 citedOpen Access
T Cells and Cytokines in Intracellular Bacterial Infections: Experiences with <i>Mycobacterium Bovis</i> BCG
Novartis Foundation symposium·2007· 27 cited
Decreased blood dendritic cell counts in type 1 diabetic children
Clinical Immunology·2007· 67 cited
Chaperonin 10 regulates the innate immune response to toll-like receptor activation
Queensland's institutional digital repository (The University of Queensland)·2007
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Frequent Co-authors

Stefan H. E. Kaufmann(22), David C. Tscharke(12), E. Ferber(10), Natasha A. Hollett(5), Yik Chun Wong(4), Günter Schwamberger(3), Brigitte F. Schmidt(3), C. Ladel(2), Gennaro De Libero(2), Nathan P. Croft(2), Stewart A. Smith(2), Leon C. W. Lin(2), Anthony W. Purcell(2), Nicole L. La Gruta(2), Jürgen H. Hess(2), Barbara Ecker(2), Yang Wang(2), Johannes Barsig(2), Bianca M. Dobson(2), Flávio Guimarães da Fonseca(2)