Shu Shu

Peking Union Medical College Hospital — China

Neuroscience · Life Sciences

23h-index1.8kcitations51works6.72yr avg
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Research Topics

Neuroinflammation and Neurodegeneration Mechanisms(18), Neuroscience and Neuropharmacology Research(12), Alzheimer's disease research and treatments(12), Inflammasome and immune disorders(5), Memory and Neural Mechanisms(4)

Publications51 total

AXL Promotes Ischemic Myelin Repair Through Alleviating Myelin Debris Deposition and Lipid Droplets Accumulation
Advanced Science·2026Open Access
Edaravone-Dexborneol slows down pathological progression and cognitive decline via inhibiting S100A9 in APPswe/PS1dE9 mice
Alzheimer s Research & Therapy·2025Open Access
Beraprost sodium ameliorates cognitive impairment by promoting oligodendrocyte precursor cell proliferation and differentiation in vascular cognitive impairment mouse model
Neuropharmacology·2025
MeCP2 Lactylation Protects against Ischemic Brain Injury by Transcriptionally Regulating Neuronal Apoptosis
Advanced Science·2025· 18 citedOpen Access
Circ_0000099/miR-223-3p/CTGF Regulates the Growth, Metastasis, and EMT Processes in TGF-β2-Stimulated Human Lens Epithelial Cells
Current Eye Research·2024· 2 cited
Comparative Analysis of Chloroplast Genome Variation and Evolutionary Analysis of the Endangered Species Dendrobium flexicaule and its Relative Species
Scientific and Social Research·2024Open Access
Impairments of GABAergic transmission in hippocampus mediate increased susceptibility of epilepsy in the early stage of Alzheimer’s disease
Cell Communication and Signaling·2024· 27 citedOpen Access
Conditional knockout of <scp>AIM2</scp> in microglia ameliorates synaptic plasticity and spatial memory deficits in a mouse model of Alzheimer's disease
CNS Neuroscience & Therapeutics·2023· 15 citedOpen Access
QHRD106 ameliorates ischemic stroke injury as a long-acting tissue kallikrein preparation
iScience·2023· 14 citedOpen Access
MiR-431 attenuates synaptic plasticity and memory deficits in APPswe/PS1dE9 mice
JCI Insight·2023· 13 citedOpen Access
Absent in melanoma 2 mediates aging‐related cognitive dysfunction by acting on complement‐dependent microglial phagocytosis
Aging Cell·2023· 15 citedOpen Access
Astrocytic CXCL5 hinders microglial phagocytosis of myelin debris and aggravates white matter injury in chronic cerebral ischemia
Journal of Neuroinflammation·2023· 54 citedOpen Access
Conditional knockout of AIM2 in microglia ameliorates synaptic plasticity and spatial memory deficits in a mouse model of Alzheimer's disease
Research Square (Research Square)·2023· 2 citedOpen Access
CD11c+ microglia promote white matter repair after ischemic stroke
Cell Death and Disease·2023· 75 citedOpen Access
Optogenetic Stimulation of mPFC Alleviates White Matter Injury‐Related Cognitive Decline after Chronic Ischemia through Adaptive Myelination
Advanced Science·2022· 41 citedOpen Access
The Complete Chloroplast Genome of Endangered Species Dendrobium flexicaule: Insight into the Phylogenetic Relationship and Conservation Implications
Research Square (Research Square)·2022Open Access
Prefrontal parvalbumin interneurons deficits mediate early emotional dysfunction in Alzheimer’s disease
Neuropsychopharmacology·2022· 35 citedOpen Access
<scp>ERK</scp> inhibition reduces neuronal death and ameliorates inflammatory responses in forebrain‐specific <i>Ppp2cα</i> knockout mice
The FASEB Journal·2022· 9 cited
JLX001 ameliorates cerebral ischemia injury by modulating microglial polarization and compromising NLRP3 inflammasome activation via the NF-κB signaling pathway
International Immunopharmacology·2021· 11 cited
AIM2 deletion enhances blood‐brain barrier integrity in experimental ischemic stroke
CNS Neuroscience & Therapeutics·2021· 73 citedOpen Access
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Frequent Co-authors

Yun Xu(18), Siyi Xu(14), Xinyu Bao(11), Junqiu Jia(10), Shengnan Xia(9), Xiaolei Zhu(9), Ling‐Qiang Zhu(8), Youming Lu(8), Xiang Cao(8), Huijie Bian(7), Huanhuan Yan(6), Lei Pei(6), Qing Tian(6), Houze Zhu(5), Na Tang(5), Yu Amanda Guo(5), Xin Yang(5), Pinyi Liu(5), Lei Ye(5), Pei Pang(4)