Erik S. Barton

Pfizer (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

21h-index3.2kcitations31works3.02yr avg
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Research Topics

Virus-based gene therapy research(13), Viral gastroenteritis research and epidemiology(12), Cytomegalovirus and herpesvirus research(11), Herpesvirus Infections and Treatments(7), Viral-associated cancers and disorders(7)

Publications31 total

High-purity AAV vector production utilizing recombination-dependent minicircle formation and genetic coupling
EMBO Molecular Medicine·2025· 4 citedOpen Access
Unraveling Cytotoxicity in HEK293 Cells During Recombinant AAV Production for Gene Therapy Applications
Biotechnology Journal·2025· 4 cited
Manufacturing, Analytical, and Process Comparability Challenges for Recombinant Adeno-Associated Virus (rAAV) Gene Therapy
2024· 1 cited
Production of rAAV by plasmid transfection induces antiviral and inflammatory responses in suspension HEK293 cells
Molecular Therapy — Methods & Clinical Development·2023· 41 citedOpen Access
Unsupervised learning techniques reveal heterogeneity in memory CD8+ T cell differentiation following acute, chronic and latent viral infections
Virology·2017· 3 cited
Type I Interferon Signaling Enhances CD8<sup>+</sup>T Cell Effector Function and Differentiation during Murine Gammaherpesvirus 68 Infection
Journal of Virology·2014· 35 citedOpen Access
Gammaherpesvirus Latency Differentially Impacts the Generation of Primary versus Secondary Memory CD8<sup>+</sup>T Cells during Subsequent Infection
Journal of Virology·2014· 17 citedOpen Access
Herpesvirus latency differentially impacts primary versus secondary memory T cell pools (P6119)
The Journal of Immunology·2013
Immune modulation during latent herpesvirus infection
Immunological Reviews·2011· 152 citedOpen Access
A Gammaherpesvirus Cooperates with Interferon-alpha/beta-Induced IRF2 to Halt Viral Replication, Control Reactivation, and Minimize Host Lethality
PLoS Pathogens·2011· 44 citedOpen Access
Pathogenesis and Host Control of Gammaherpesviruses: Lessons from the Mouse
Annual Review of Immunology·2011· 252 cited
Herpesvirus Latency and Symbiotic Protection from Bacterial Infection
Viral Immunology·2009· 21 cited
(C)Re-Combining Textbook Models of Virus Spread within the Host
Cell Host & Microbe·2008Open Access
Herpesvirus latency confers symbiotic protection from bacterial infection
Nature·2007· 752 citedOpen Access
Reovirus Delays Diabetes Onset but Does Not Prevent Insulitis in Nonobese Diabetic Mice
Journal of Virology·2006· 20 citedOpen Access
Gamma Interferon Blocks Gammaherpesvirus Reactivation from Latency
Journal of Virology·2005· 83 citedOpen Access
Alpha/Beta Interferons Regulate Murine Gammaherpesvirus Latent Gene Expression and Reactivation from Latency
Journal of Virology·2005· 98 citedOpen Access
Organ-specific roles for transcription factor NF-κB in reovirus-induced apoptosis and disease
Journal of Clinical Investigation·2005· 83 citedOpen Access
Disruption of Erk-dependent type I interferon induction breaks the myxoma virus species barrier
Nature Immunology·2004· 179 citedOpen Access
Isolation and Molecular Characterization of a Novel Type 3 Reovirus from a Child with Meningitis
The Journal of Infectious Diseases·2004· 97 citedOpen Access
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Frequent Co-authors

Terence S. Dermody(12), Jodi L. Connolly(7), Douglas W. White(6), J. Craig Forrest(6), James D. Chappell(6), J. Denise Wetzel(6), Herbert W. Virgin(5), Tibor Vályi-Nagy(4), Jason M. Grayson(4), Ryan Jennings(3), Pratyusha Mandal(2), R. Suzanne Beard(2), Steven E. Rodgers(2), Kenneth L. Tyler(2), Mary L. Lutzke(2), Rosemary Rochford(2), Bryan Youree(2), Daniel H. Ebert(2), Kay Washington(2), Geoffrey S. Baer(2)