Nigel Irwin

University of Ulster — United Kingdom

Medicine · Health Sciences

44h-index6.7kcitations303works1.72yr avg
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Research Topics

Diabetes Treatment and Management(192), Pancreatic function and diabetes(142), Neuropeptides and Animal Physiology(103), Metabolism, Diabetes, and Cancer(50), Regulation of Appetite and Obesity(44)

Publications301 total

Kisspeptin-10 Ameliorates Obesity-Diabetes with Diverse Effects on Ileal Enteroendocrine Cells and Pancreatic Islet Morphology in High-Fat Fed Female Mice
Biomolecules·2025· 1 citedOpen Access
Impact of novel amino acid substituted and acylated spexin analogues on pancreatic beta-cell function, appetite and glucose homeostasis
Molecular and Cellular Endocrinology·2025Open Access
Effect of Multiparity on Pregnancy-Induced Islet Adaptation and Cellular Transdifferentiation
Clinical Medicine Insights Endocrinology and Diabetes·2025· 1 citedOpen Access
The Beneficial Impact of a Novel Pancreatic Polypeptide Analogue on Islet Cell Lineage
International Journal of Molecular Sciences·2025· 2 citedOpen Access
Islet effects of cholecystokinin and exploitation in diabetes
Elsevier eBooks·2025
Contributors
Elsevier eBooks·2025Open Access
Pharmacy student confidence, knowledge and teaching experience in diabetes related pharmacology and therapeutics
Pharmacy Education·2024Open Access
Comparative Effects of GLP-1 and GLP-2 on Beta-Cell Function, Glucose Homeostasis and Appetite Regulation
Biomolecules·2024· 4 citedOpen Access
Gut-derived peptides and bone disorders in obesity and diabetes
Endocrine Abstracts·2024
Novel unimolecular peptides targeting GLP-1 and APJ receptors exert potent satiety inducing effects in mice
Endocrine Abstracts·2024
Hybrid acylated and non-acylated GLP-1 and apelin receptor co-agonist peptides, show promising acute <i>in vivo</i> anti-hyperglycaemic actions in normal healthy and insulin resistant diet-induced obese mice
Endocrine Abstracts·2024
Differential impact of GLP-1 and GLP-2 on beta-cell function, glucose metabolism, and appetite
Endocrine Abstracts·2024· 3 cited
Pregnancy induced pancreatic islet expansion is compromised by consumption of cafeteria diet
Endocrine Abstracts·2024
Cafeteria diet compromises natural adaptations of islet cell transdifferentiation and turnover in pregnancy
Diabetic Medicine·2024· 2 citedOpen Access
[ <scp> P <sup>3</sup> </scp> ] <scp>PP</scp> , a stable, long‐acting pancreatic polypeptide analogue, evokes weight lowering and pancreatic beta‐cell‐protective effects in obesity‐associated diabetes
Diabetes Obesity and Metabolism·2024· 2 citedOpen Access
Author response for "[&lt;scp&gt;P&lt;sup&gt;3&lt;/sup&gt;&lt;/scp&gt;]&lt;scp&gt;PP&lt;/scp&gt;, a stable, long‐acting pancreatic polypeptide analogue, evokes weight lowering and pancreatic beta‐cell‐protective effects in obesity‐associated diabetes"
2024
Author response for "[&lt;scp&gt;P&lt;sup&gt;3&lt;/sup&gt;&lt;/scp&gt;]&lt;scp&gt;PP&lt;/scp&gt;, a stable, long‐acting pancreatic polypeptide analogue, evokes weight lowering and pancreatic beta‐cell‐protective effects in obesity‐associated diabetes"
2024
Does glucose-dependent insulinotropic polypeptide receptor blockade as well as agonism have a role to play in management of obesity and diabetes?
Journal of Endocrinology·2024· 5 citedOpen Access
NPYR modulation: Potential for the next major advance in obesity and type 2 diabetes management?
Peptides·2024· 3 citedOpen Access
Chronic exposure to incretin metabolites GLP-1(9−36) and GIP(3−42) affect islet morphology and beta cell health in high fat fed mice
Peptides·2024· 2 citedOpen Access
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Frequent Co-authors

Peter R. Flatt(46), Victor A. Gault(25), Finbarr O’Harte(13), Daniel Chappard(9), Guillaume Mabilleau(9), Brian D. Green(8), Patrick Harriott(8), Brett Greer(7), Clifford J. Bailey(7), A. Mieczkowska(7), R. Charlotte Moffett(5), Paula L. McClean(4), Varun Pathak(4), Sity Aishah Mansur(3), David W. Porter(3), Dawood Khan(3), Ryan A. Lafferty(3), Stephen McClean(3), Roslyn Cassidy(2), Jane T. McCluskey(2)