Claus‐Michael Lehr

Universität Hamburg — Germany

Medicine · Health Sciences

94h-index30.9kcitations558works3.82yr avg
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Research Topics

Inhalation and Respiratory Drug Delivery(126), Advanced Drug Delivery Systems(114), Advancements in Transdermal Drug Delivery(72), RNA Interference and Gene Delivery(71), Nanoparticle-Based Drug Delivery(52)

Publications558 total

Impact and dynamics of monocyte and platelet activation on clinical outcomes in patients under immune checkpoint inhibitors.
Hämostaseologie·2026
pH‐Responsive Isoprenoid‐Antitumoral Polymer Conjugates for Superior Drug Loading via Self‐Assembly and Endosomal‐Targeted Anticancer Activity
ChemMedChem·2026Open Access
Polymer Blend Controls Nanoparticles’ Surface Charge for Improved Mucus Penetration and Epithelial Cell Adhesion
Nano Letters·2025
Toward Anti‐Herpesviral PROTACs: Assessing the Challenges for Targeted Protein Degradation on the Example of Kaposi's Sarcoma‐Associated Herpesvirus Latency‐Associated Nuclear Antigen
ChemMedChem·2025· 1 citedOpen Access
Leukocytic ADAM10 and ADAM17 modulate disease severity and systemic outcome in bacterial and viral pneumonia
European Respiratory Journal·2025· 1 citedOpen Access
Mapping the ABC transporter landscape in the human lung: A comprehensive characterisation of P-gp, MRP1 and BCRP expression and functional activity in human lung epithelial cells
European Journal of Pharmaceutical Sciences·2025· 2 citedOpen Access
Nanoparticles across mucosal barriers: Differentiating mucoadhesion from mucopenetration using single particle tracking
Journal of Controlled Release·2025Open Access
Soft mist inhaler nebulization by Rayleigh-breakup largely preserves functional integrity of liposomal mRNA in respirable aerosols
European Journal of Pharmaceutical Sciences·2025· 1 citedOpen Access
Proteomic profiling of macrophages: effects of inflammatory activation and anti-inflammatory treatment with IBD therapeutics
European Journal of Pharmaceutics and Biopharmaceutics·2025· 1 cited
The role of ABC transporters in the human lung epithelium—insights from and limitations of current in vitro cell models
In vitro models·2025· 2 citedOpen Access
Exploring the future of mRNA delivery: Beyond lipid nanoparticles
Biochemical and Biophysical Research Communications·2025· 1 citedOpen Access
Extracellular vesicles and their RNA cargo facilitate bidirectional cross-kingdom communication between human and bacterial cells
2025· 1 citedOpen Access
Direct monitoring of intracellular polymer degradation via BODIPY dynamic dequenching
Materials & Design·2025· 2 citedOpen Access
A novel lipopolyplex platform for dual mRNA delivery via core- and surface-loading
Journal of Controlled Release·2025· 4 citedOpen Access
Tobramycin crosslinking improves the colloidal stability of arginine chitosan biodynamers for safe and efficient siRNA delivery
International Journal of Biological Macromolecules·2025· 1 citedOpen Access
Editorial to ‘Bio-material interfaces and Drug Delivery’
European Journal of Pharmaceutics and Biopharmaceutics·2025
Thiol isomerase inhibition with bacitracin or rutin interferes with tissue factor production in myelomonocytic HL-60 cells and isolated AML blasts
Hämostaseologie·2025
Antimicrobial and antibiotic-potentiating effect of calcium peroxide nanoparticles on oral bacterial biofilms
npj Biofilms and Microbiomes·2024· 3 citedOpen Access
SIMPLIFIED ONE-DIMENSIONAL MODEL FOR TRANSIENT TIME-DOMAIN SIMULATION OF CENTRIFUGAL PUMPS
2024· 2 cited
A Strategic Blend of Stabilizing Polymers to Control Particle Surface Charge for Enhanced Mucus Transport and Cell Binding
2024· 1 citedOpen Access
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Frequent Co-authors

Ulrich F. Schaefer(13), Hans E. Junginger(7), Eva-Maria Collnot(7), Marc Schneider(5), Alf Lamprecht(4), Ulrich Schäfer(4), Udo Bakowsky(4), J. Coos Verhoef(4), Mohammad Sameti(4), Julian Kirch(4), Brigitta Loretz(3), Nathalie Ubrich(3), Philippe Maincent(3), Albertus G. de Boer(3), Carsten Kneuer(3), Helmut K. Schmidt(3), Nicole Schneider‐Daum(3), Hanno Huwer(3), Christiane Baldes(3), Michael F. Wempe(3)