James B. Kaper

University of Maryland, Baltimore — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

115h-index57.6kcitations453works0.02yr avg
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Research Topics

Escherichia coli research studies(273), Vibrio bacteria research studies(166), Viral gastroenteritis research and epidemiology(144), Bacterial Genetics and Biotechnology(73), Aquaculture disease management and microbiota(70)

Publications453 total

A history of <i>EcoSal Plus</i>
EcoSal Plus·2025Open Access
Mo1874 HOST EPITHELIAL ADHERENCE AND CXCL5/CXCR2 MEDIATE INTESTINAL MACROPHAGE RECOGNITION OF ENTEROTOXIGENIC E. COLI
Gastroenterology·2023
Mucosal Immune Profiles Associated with Diarrheal Disease Severity in<i>Shigella</i>- and Enteropathogenic Escherichia coli-Infected Children Enrolled in the Global Enteric Multicenter Study
mBio·2022· 13 citedOpen Access
Cross-Talk between Probiotic Nissle 1917 and Human Colonic Epithelium Affects the Metabolite Composition and Demonstrates Host Antibacterial Effect
Metabolites·2021· 3 citedOpen Access
Human Epithelial Stem Cell-Derived Colonoid Monolayers as a Model to Study Shiga Toxin-Producing Escherichia coli–Host Interactions
Methods in molecular biology·2021· 7 cited
Coronin-1 is necessary for enteric pathogen-induced transcytosis across human ileal enteroid monolayers expressing M cells
2020· 4 citedOpen Access
Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic <i>Escherichia coli</i> infection
Gut Microbes·2020· 21 citedOpen Access
Mechanical Stimuli Affect Escherichia coli Heat-Stable Enterotoxin-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Model
Infection and Immunity·2019· 40 citedOpen Access
Su1012 – Mechanical Stimuli Affect Enterotoxigenic E. Coli (ETEC) Heat Stable Enterotoxin (ST)-Cyclic Nucleotide Signaling by Altering Mrp4 Expression in a Human Enteroid Monolayer Model of Etec Diarrhea
Gastroenterology·2019
Enterohemorrhagic E. coli (EHEC)—Secreted Serine Protease EspP Stimulates Electrogenic Ion Transport in Human Colonoid Monolayers
Toxins·2018· 24 citedOpen Access
789 - Enteric Pathogens Induce M Cell Transcytosis in a Human Enteroid Model of the Follicle Associated Epithelium
Gastroenterology·2018
Tandem tyrosine phosphosites in the Enteropathogenic <i>Escherichia coli</i> chaperone CesT are required for differential type III effector translocation and virulence
Molecular Microbiology·2018· 10 citedOpen Access
Phosphotyrosine-Mediated Regulation of Enterohemorrhagic <i>Escherichia coli</i> Virulence
mBio·2018· 11 citedOpen Access
Tandem tyrosine residues in the EPEC multicargo chaperone CesT support differential type III effector translocation and early host colonization
2018Open Access
Enteropathogenic Escherichia coli EspH-Mediated Rho GTPase Inhibition Results in Desmosomal Perturbations
Cellular and Molecular Gastroenterology and Hepatology·2018· 14 citedOpen Access
Enterotoxigenic <i>Escherichia coli</i> is phagocytosed by macrophages underlying villus-like intestinal epithelial cells: modeling ex vivo innate immune defenses of the human gut
Gut Microbes·2017· 24 citedOpen Access
PaxVax CVD 103-HgR single-dose live oral cholera vaccine
Expert Review of Vaccines·2017· 66 citedOpen Access
Editorial: Infection and immunity research at the University of Maryland, Baltimore
Pathogens and Disease·2016Open Access
Oral Cholera Vaccines
2016· 4 cited
Genomic diversity of EPEC associated with clinical presentations of differing severity
Nature Microbiology·2016· 91 citedOpen Access
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Frequent Co-authors

Michael S. Donnenberg(12), James P. Nataro(9), Vanessa Sperandio(6), Myron M. Levine(6), Jorge A. Girón(6), Ben D. Tall(5), M. M. Levine(4), Alfredo G. Torres(4), Simon J. Elliott(4), Karen G. Jarvis(3), Ann E. Jerse(3), Jiaao Yu(3), Pablo Vial(3), Timothy K. McDaniel(3), M L Clements(3), Jay L. Mellies(3), Rita R. Colwell(3), Mary M. Baldini(3), J. Glenn Morris(2), T K McDaniel(2)