Pedro M. Alzari

Centre National de la Recherche Scientifique — France

Biochemistry, Genetics and Molecular Biology · Life Sciences

69h-index14.1kcitations374works1.22yr avg
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Research Topics

Biochemical and Molecular Research(87), Enzyme Structure and Function(86), Tuberculosis Research and Epidemiology(63), Glycosylation and Glycoproteins Research(59), Bacterial Genetics and Biotechnology(43)

Publications374 total

Deep learning extracts MoA-specific signatures from high-throughput images of chemically and genetically perturbed <i>Corynebacteria</i>
2026Open Access
Mechanistic insights into SteAB regulation of cell wall hydrolase RipA in <i>Mycobacterium tuberculosis</i>
mBio·2026Open Access
Functional dissection of Wag31 domains for septal recruitment and polar distribution during the cell cycle
2025Open Access
Mechanistic insights into the allosteric regulation of cell wall hydrolase RipA in <i>Mycobacterium tuberculosis</i>
2025· 2 citedOpen Access
FhaA plays a key role in mycobacterial polar elongation and asymmetric growth
mBio·2025· 2 citedOpen Access
Towards Improved Peptidic α‐Ketoamide Inhibitors of the Plasmodial Subtilisin‐Like SUB1: Exploration of <i>N</i>‐Terminal Extensions and Cyclic Constraints
ChemMedChem·2025· 1 citedOpen Access
Evolutionary plasticity and functional repurposing of the essential metabolic enzyme MoeA
Communications Biology·2025· 1 citedOpen Access
Molecular mechanism of a triazole-containing inhibitor of Mycobacterium tuberculosis DNA gyrase
iScience·2024· 4 citedOpen Access
Structural insights into cell septation in <i>Mycobacterium tuberculosis</i>
Acta Crystallographica Section A Foundations and Advances·2024
FhaA plays a key role in mycobacterial polar elongation and asymmetric growth
2024Open Access
Evolutionary plasticity and functional repurposing of the essential metabolic enzyme MoeA
2024Open Access
Insights from structure-activity relationships and the binding mode of peptidic α-ketoamide inhibitors of the malaria drug target subtilisin-like SUB1
European Journal of Medicinal Chemistry·2024· 4 citedOpen Access
Complete genome sequence of <i>Bradyrhizobium</i> sp. 62B, a native nitrogen-fixing rhizobium isolated from peanut nodules
Microbiology Resource Announcements·2024Open Access
Prodomain-driven enzyme dimerization: a pH-dependent autoinhibition mechanism that controls <i>Plasmodium</i> Sub1 activity before merozoite egress
mBio·2024· 3 citedOpen Access
Genome sequence of <i>Mesorhizobium mediterraneum</i> strain R31, a nitrogen-fixing rhizobium used as an inoculant for chickpea in Argentina
Microbiology Resource Announcements·2023· 1 citedOpen Access
Eukaryotic-like gephyrin and cognate membrane receptor coordinate corynebacterial cell division and polar elongation
Nature Microbiology·2023· 17 citedOpen Access
High resolution cryo-EM and crystallographic snapshots of the actinobacterial two-in-one 2-oxoglutarate dehydrogenase
Nature Communications·2023· 13 citedOpen Access
Prodomain-driven enzyme dimerization, a potent pH-dependent autoinhibition mechanism to control <i>Plasmodium</i> Sub1 subtilisin-like activity prior to prime merozoite egress
2023· 1 citedOpen Access
3D structures of the <i>Plasmodium vivax</i> subtilisin-like drug target SUB1 reveal conformational changes to accommodate a substrate-derived α-ketoamide inhibitor
Acta Crystallographica Section D Structural Biology·2023· 4 citedOpen Access
Whole-Genome Sequence of Burkholderia ambifaria Strain Q53, a Potential Plant Growth Promoter Isolated from the Rhizosphere of Peanut
Microbiology Resource Announcements·2023Open Access
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Frequent Co-authors

Stewart T. Cole(9), Alejandro Buschiazzo(8), Anne Marie Wehenkel(6), Hélène Souchon(6), Francis Schaeffer(6), Pablo Fernández(5), Mary Jackson(5), Marco Bellinzoni(5), Rosario Durán(5), Carlos Červeñanský(5), Marcelo E. Guerin(5), Pierre Béguin(4), Brigitte Boitel(4), Roberto J. Poljak(3), Marie‐Bernard Lascombe(3), Alberto C.C. Frasch(3), R J Poljak(3), Brigitte Saint‐Joanis(3), M. Ortiz-Lombardı́a(3), H. Souchon(3)