Micah J. Niphakis

Scripps Institution of Oceanography — United States

Medicine · Health Sciences

34h-index4.1kcitations86works9.32yr avg
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Research Topics

Cannabis and Cannabinoid Research(30), Neurotransmitter Receptor Influence on Behavior(11), Neuroscience and Neuropharmacology Research(7), HIV Research and Treatment(7), Forensic Toxicology and Drug Analysis(7)

Publications86 total

Mitochondrial ABHD11 inhibition drives sterol metabolism to modulate T-cell effector function
Nature Communications·2025Open Access
Genetic suppression features ABHD18 as a Barth syndrome therapeutic target
Nature·2025· 4 cited
<i>In vivo</i> validation of the palmitoylation cycle as a therapeutic target in <i>NRAS</i> -mutant cancer
2025Open Access
ABHD11 inhibition drives sterol metabolism to modulate T cell effector function and alleviate autoimmunity
2025Open Access
Attenuating ABHD17 Isoforms Augments the S-acylation and Function of NOD2 and a Subset of Crohn’s Disease-associated NOD2 Variants
Cellular and Molecular Gastroenterology and Hepatology·2025· 6 citedOpen Access
<i>In Vivo</i> and <i>In Vitro</i> Chemical Synthetic Lethality of ABHD17 and MEK Inhibition in <i>NRAS</i>-Mutant Acute Myeloid Leukemia
Blood·2024· 2 cited
Ligand discovery by activity-based protein profiling
Cell chemical biology·2024· 46 citedOpen Access
Inflammation causes insulin resistance in mice via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels
Nature Communications·2024· 23 citedOpen Access
A helping HAND: therapeutic potential of MAGL inhibition against HIV-1-associated neuroinflammation
Frontiers in Immunology·2024· 3 citedOpen Access
Attenuating ABHD17 isoforms augments the <i>S</i> -acylation and function of NOD2 and a subset of Crohn’s disease-associated NOD2 variants
2023· 6 citedOpen Access
Inflammation causes insulin resistance via interferon regulatory factor 3 (IRF3)-mediated reduction in FAHFA levels
2023· 2 citedOpen Access
Stimulatory effect of monoacylglycerol lipase inhibitor MJN110 on locomotion and step kinematics demonstrated by high-precision 3D motion capture in mice
2023· 4 citedOpen Access
Chemoproteomic identification of a DPP4 homolog in Bacteroides thetaiotaomicron
Nature Chemical Biology·2023· 25 cited
Chemoproteomic identification of a DPP4 homolog in Bacteroides thetaiotaomicron
Zenodo (CERN European Organization for Nuclear Research)·2023Open Access
Chemoproteomic identification of a dipeptidyl peptidase 4 (DPP4) homolog in Bacteroides thetaiotaomicron important for envelope integrity and fitness
Research Square (Research Square)·2022Open Access
Chemoproteomic identification of a dipeptidyl peptidase 4 (DPP4) homolog in <i>Bacteroides thetaiotaomicron</i> important for envelope integrity and fitness
2022Open Access
Ace-ylation in the hole
Nature Chemical Biology·2022
Inhibitory Neurotransmission Is Sex-Dependently Affected by Tat Expression in Transgenic Mice and Suppressed by the Fatty Acid Amide Hydrolase Enzyme Inhibitor PF3845 via Cannabinoid Type-1 Receptor Mechanisms
UNC Libraries·2022· 1 citedOpen Access
Inhibitory Neurotransmission Is Sex-Dependently Affected by Tat Expression in Transgenic Mice and Suppressed by the Fatty Acid Amide Hydrolase Enzyme Inhibitor PF3845 via Cannabinoid Type-1 Receptor Mechanisms
Cells·2022· 15 citedOpen Access
Monoacylglycerol Lipase Inhibitor MJN110 Reduces Neuronal Hyperexcitability, Restores Dendritic Arborization Complexity, and Regulates Reward-Related Behavior in Presence of HIV-1 Tat
Frontiers in Neurology·2021· 17 citedOpen Access
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Frequent Co-authors

Benjamin F. Cravatt(38), Aron H. Lichtman(14), Armand B. Cognetta(8), Rehab A. Abdullah(8), Kenneth M. Lum(7), Gunda I. Georg(7), Bogna M. Ignatowska‐Jankowska(7), Nhi Ngo(6), Justin L. Poklis(5), Cheryl L. Limebeer(5), Linda A. Parker(5), Cassandra L. Henry(4), Jenny L. Wiley(4), Jenny L. Wilkerson(4), Mohammed Ahmed Mustafa(4), Sylvia Fitting(4), Erin M. Rock(4), Jae Won Chang(3), Matthew W. Buczynski(3), Loren H. Parsons(3)