Xiaoxi Zhuang

Guangzhou Institutes of Biomedicine and Health — China

Neuroscience · Life Sciences

50h-index11.6kcitations112works3.12yr avg
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Research Topics

Neurotransmitter Receptor Influence on Behavior(34), Receptor Mechanisms and Signaling(29), Parkinson's Disease Mechanisms and Treatments(21), Neuroscience and Neuropharmacology Research(18), Neurological disorders and treatments(12)

Publications112 total

Discovery of novel indole derivatives as LRH-1 antagonists for the treatment of castration resistant prostate cancer
European Journal of Medicinal Chemistry·2026
Deciphering the intermolecular interactions between G-quadruplex (G4)-forming sequences
Nucleic Acids Research·2025· 1 citedOpen Access
A cell-autonomous role for the vitamin B6 metabolism gene <i>PNPO</i> in <i>Drosophila</i> GABAergic neurons
Journal of Neurogenetics·2025
A Cell-Autonomous Role for the Vitamin B6 Metabolism Gene <i>PNPO</i> in <i>Drosophila</i> GABAergic Neurons
2025Open Access
Erasing “bad memories”: reversing aberrant synaptic plasticity as therapy for neurological and psychiatric disorders
Molecular Psychiatry·2025· 2 citedOpen Access
Promising Proteolysis-Targeting Chimera for Mutant p53-R175H
ACS Omega·2024· 2 citedOpen Access
Cause-Aware Empathetic Response Generation via Chain-of-Thought Fine-Tuning
arXiv (Cornell University)·2024Open Access
YTHDF1 mediates translational control by m6A mRNA methylation in adaptation to environmental challenges
2024· 1 citedOpen Access
m6A RNA methylation regulates mitochondrial function
Human Molecular Genetics·2024· 24 citedOpen Access
Opposing Motor Memories in the Direct and Indirect Pathways of the Basal Ganglia
2024· 1 citedOpen Access
FMRP phosphorylation modulates neuronal translation through YTHDF1
Molecular Cell·2023· 74 citedOpen Access
Learning critically drives parkinsonian motor deficits through imbalanced striatal pathway recruitment
Proceedings of the National Academy of Sciences·2023· 42 citedOpen Access
Discovery and Characterization of 1-Ethylindolin-2-One Derivatives as BRD4 Bromodomain Inhibitors for the Treatment of Prostate Cancer
SSRN Electronic Journal·2023Open Access
FMRP phosphorylation modulates neuronal translation through YTHDF1
2022· 7 citedOpen Access
Trapping of Nicotinic Acetylcholine Receptor Ligands Assayed by <i>In Vitro</i> Cellular Studies and <i>In Vivo</i> PET Imaging
Journal of Neuroscience·2022· 9 citedOpen Access
Reader Response: Safety of AADC Gene Therapy for Moderately Advanced Parkinson Disease: Three-Year Outcomes From the PD-1101 Trial
Neurology·2022· 1 citedOpen Access
Correction to: Pyridox (am) ine 5'-phosphate oxidase deficiency induces seizures in <i>Drosophila melanogaster</i>
Human Molecular Genetics·2022Open Access
<i>Drosophila</i> carrying epilepsy-associated variants in the vitamin B6 metabolism gene <i>PNPO</i> display allele- and diet-dependent phenotypes
Proceedings of the National Academy of Sciences·2022· 17 citedOpen Access
Trapping of Nicotinic Acetylcholine Receptor Ligands Assayed by <i>in vitro</i> Cellular Studies and <i>in vivo</i> PET Imaging
2021· 1 citedOpen Access
Author response: Partial connectomes of labeled dopaminergic circuits reveal non-synaptic communication and axonal remodeling after exposure to cocaine
2021Open Access
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Frequent Co-authors

René Hen(10), Jeff A. Beeler(10), Un Jung Kang(7), Chuan He(6), Barbara Cagniard(6), Linan Chen(5), Guo‐li Ming(4), Yunmin Ding(4), Daniel S. McGehee(4), Cornelius T. Gross(3), Luca Santarelli(3), Peng Jin(3), Hongjun Song(3), Hailing Shi(3), Mark A. Geyer(3), Dani Brunner(3), Susie Turkson(3), Jessica L. Koranda(3), Rae Silver(3), Ronald S. Oosting(2)