Thomas Sheffield

Sandia National Laboratories California — United States

Medicine · Health Sciences

12h-index597citations32works1.12yr avg
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Research Topics

Cancer Immunotherapy and Biomarkers(6), Gene expression and cancer classification(4), Immune Cell Function and Interaction(4), Computational Drug Discovery Methods(3), Thyroid Cancer Diagnosis and Treatment(2)

Publications32 total

Integrative multi-omic and phenotypic analysis of open raceway pond production of Monoraphidium minutum 26B-AM reveals distinct stress signatures for scale-up and infection
Biotechnology for Biofuels and Bioproducts·2026Open Access
Iterative ML and Experiments for Emerging VOCs
OSTI OAI (U.S. Department of Energy Office of Scientific and Technical Information)·2026Open Access
Integrative multi-omic and phenotypic analysis of open raceway pond production of <i>Monoraphidium minutum</i> 26B-AM reveals distinct stress signatures for scale-up and infection
2025Open Access
Machine learning guided selection of broad-spectrum epitope-specific functional antibodies for "Disease X"
2025Open Access
Nanobody screening and machine learning guided identification of cross-variant anti-SARS-CoV-2 neutralizing heavy-chain only antibodies
PLoS Pathogens·2025· 2 citedOpen Access
A Machine Learning Model Predicts Antibody-Virus Interactions And Identifies Existing Antibodies that Neutralize Emerging Viral Threats
2024Open Access
Highly variable timing renders immunotherapy efficacy and toxicity impractical biomarkers of one another in clinical practice
Frontiers in Immunology·2024· 6 citedOpen Access
Systemic immune parameters after prior radiation therapy in patients receiving immune checkpoint inhibitors
Translational Oncology·2023· 1 citedOpen Access
Experimental and Modeling Informed Data Analytics Platform to Identify Viral Features Indicative of Pandemic Potential.
2022Open Access
Correction to: Divergent prognostic effects of pre-existing and treatment-emergent thyroid dysfunction in patients treated with immune checkpoint inhibitors
Cancer Immunology Immunotherapy·2022· 2 citedOpen Access
Association between Antibiotic Exposure and Systemic Immune Parameters in Cancer Patients Receiving Checkpoint Inhibitor Therapy
Cancers·2022· 21 citedOpen Access
Divergent prognostic effects of pre-existing and treatment-emergent thyroid dysfunction in patients treated with immune checkpoint inhibitors
Cancer Immunology Immunotherapy·2022· 30 citedOpen Access
tcplfit2: an R-language general purpose concentration–response modeling package
Bioinformatics·2021· 42 citedOpen Access
Association of Healthcare Access With Intensive Care Unit Utilization and Mortality in Patients of Hispanic Ethnicity Hospitalized With COVID‐19
Journal of Hospital Medicine·2021· 27 citedOpen Access
tcplfit2: A Concentration-Response Modeling Utility
2021· 3 citedOpen Access
Association between body mass index, dosing strategy, and efficacy of immune checkpoint inhibitors
Journal for ImmunoTherapy of Cancer·2021· 39 citedOpen Access
Experience, Perceptions, and Recommendations Concerning COVID-19–Related Clinical Research Adjustments
Journal of the National Comprehensive Cancer Network·2021· 23 citedOpen Access
High-Throughput Transcriptomics Platform for Screening Environmental Chemicals
Toxicological Sciences·2021· 177 citedOpen Access
Spatial molecular profiling: platforms, applications and analysis tools
Briefings in Bioinformatics·2020· 49 citedOpen Access
Ensemble QSAR Modeling to Predict Multispecies Fish Toxicity Lethal Concentrations and Points of Departure
Environmental Science & Technology·2019· 61 citedOpen Access
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Frequent Co-authors

Yang Xie(8), David E. Gerber(7), Mitchell S. von Itzstein(6), Farjana Fattah(6), Yiqing Wang(6), Richard Judson(5), Amrit S. Gonugunta(4), Kenneth L. Sale(4), Brooke Harmon(4), Jason Y. Park(3), Vinita Popat(3), David Hsiehchen(3), Quan‐Zhen Li(3), Edward K. Wakeland(3), Jade Homsi(3), Jonathan E. Dowell(3), Stephen Won(3), Ryan C. Bruneau(3), Derik E. Haggard(2), Minzhe Zhang(2)