Jonathan J. Miner

University of Pennsylvania — United States

Immunology and Microbiology · Life Sciences

36h-index7.8kcitations94works7.22yr avg
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Research Topics

interferon and immune responses(26), Mosquito-borne diseases and control(23), Viral Infections and Vectors(20), Inflammasome and immune disorders(12), Systemic Lupus Erythematosus Research(9)

Publications94 total

Neuroimaging Biomarkers of Disease Progression and Cognitive Change in Patients With Retinal Vasculopathy With Cerebral Leukoencephalopathy
Neurology·2026
CD14-deficiency protects against osteoarthritic subchondral bone sclerosis via enhanced osteoclastogenesis following joint injury
2026Open Access
Cell-Specific Inducible Human <i>APOL1</i> Risk Variant Expression in Mice Causes Hypertension and Renal Damage
Circulation·2025Open Access
The intersection of TREX1, cGAS, STING and the DNA damage theory of aging
Frontiers in Aging·2025Open Access
Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses
Cell·2025· 2 citedOpen Access
<i>Drosophila melanogaster</i> model of RVCL-S demonstrates age dependent disease progression
2025Open Access
Limiting endosomal damage sensing reduces inflammation triggered by lipid nanoparticle endosomal escape
Nature Nanotechnology·2025· 28 citedOpen Access
Misdirected yet intact TREX1 exonuclease activity causes human cerebral and systemic small vessel disease
Brain·2025· 5 citedOpen Access
ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation
Cell·2025· 14 cited
Distinct components of mRNA vaccines cooperate to instruct efficient germinal center responses
Repository of the Academy's Library (Library of the Hungarian Academy of Sciences)·2025
Crizanlizumab for retinal vasculopathy with cerebral leukoencephalopathy in a phase II clinical study
Journal of Clinical Investigation·2024· 6 citedOpen Access
Prime Editor Gene Therapy and TREX1 Mosaicism in Retinal Vasculopathy with Cerebral Leukoencephalopathy
Journal of Clinical Immunology·2024· 4 citedOpen Access
The critical role of endoplasmic reticulum stress and the stimulator of interferon genes (STING) pathway in kidney fibrosis
Kidney International·2024· 23 citedOpen Access
Multi-stage-mixing to control the supramolecular structure of lipid nanoparticles, thereby creating a core-then-shell arrangement that improves performance by orders of magnitude
2024· 7 citedOpen Access
The prototypical interferonopathy: Aicardi‐Goutières syndrome from bedside to bench
Immunological Reviews·2024· 13 citedOpen Access
Inherited C-terminal TREX1 variants disrupt homology-directed repair to cause senescence and DNA damage phenotypes in Drosophila, mice, and humans
Nature Communications·2024· 20 citedOpen Access
POS0378 HETEROZYGOUS LOSS-OF-FUNCTION RELA MUTATIONS LEAD TO SYSTEMIC LUPUS ERYTHEMATOSUS OR AUTOINFLAMMATORY SYNDROME
Annals of the Rheumatic Diseases·2024
Stimulator of Interferon Genes (STING) Mediates Endoplasmic Reticulum Stress Activation Causing Renal Fibroinflammation
Journal of the American Society of Nephrology·2023
Regulation of cGAS and STING signaling during inflammation and infection
Journal of Biological Chemistry·2023· 58 citedOpen Access
Liver pathology in retinal vasculopathy with cerebral leukoencephalopathy and systemic manifestations: vasculopathic disease beyond nodular regenerative hyperplasia
Human Pathology·2023· 2 cited
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Frequent Co-authors

Michael Diamond(16), Amber M. Smith(10), Derek J. Platt(10), Cathrine A. Miner(8), Rodger P. McEver(6), Wei Qian(6), Tadayuki Yago(5), William A. Stinson(5), Megan T. Baldridge(5), Subhajit Poddar(5), Helen M. Lazear(4), Brock G. Bennion(4), Teresa L. Ai(4), Stefan T. Peterson(4), Jennifer Govero(3), Estefanı́a Fernández(3), Deborah J. Lenschow(3), Justin M. Richner(3), Lijun Xia(3), Rachel Rodgers(3)