Akira Ainai

National Institute of Infectious Diseases — Japan

Medicine · Health Sciences

30h-index2.6kcitations106works6.92yr avg
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Research Topics

Influenza Virus Research Studies(38), Respiratory viral infections research(30), Immune Response and Inflammation(23), SARS-CoV-2 and COVID-19 Research(21), Asthma and respiratory diseases(13)

Publications106 total

Key success factors in clinical trial operation of the smallpox vaccine LC16m8 against mpox in Colombia
Global Health & Medicine·2025· 2 citedOpen Access
LC16m8 for Pre-exposure Prophylaxis Against Mpox in a High-Risk Population: An Open-Label Randomized Trial
Clinical Infectious Diseases·2025· 9 cited
Necroptosis in alveolar epithelial cells drives lung inflammation and injury caused by SARS-CoV-2 infection
Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease·2024· 7 cited
Prophylactic vaccination inducing anti-Env antibodies can result in protection against HTLV-1 challenge in macaques
Molecular Therapy·2024· 3 citedOpen Access
Diverse pro-inflammatory ability of mutated spike protein derived from variant strains of SARS-CoV-2
Cytokine·2024· 2 cited
Mpox Neutralizing Antibody Response to LC16m8 Vaccine in Healthy Adults
NEJM Evidence·2024· 28 cited
Extraction of the CDRH3 sequence of the mouse antibody repertoire selected upon influenza virus infection by subtraction of the background antibody repertoire
Journal of Virology·2024· 3 citedOpen Access
Author Correction: Immune response and protective efficacy of the SARS-CoV-2 recombinant spike protein vaccine S-268019-b in mice
Scientific Reports·2024· 1 citedOpen Access
Infectious virus shedding duration reflects secretory IgA antibody response latency after SARS-CoV-2 infection
Proceedings of the National Academy of Sciences·2023· 44 citedOpen Access
Apple-shaped obesity: A risky soil for cytokine-accelerated severity in COVID-19
Proceedings of the National Academy of Sciences·2023· 13 citedOpen Access
Saturation time of exposure interval for cross-neutralization response to SARS-CoV-2: Implications for vaccine dose interval
iScience·2023· 6 citedOpen Access
Estimating serum cross-neutralizing responses to SARS-CoV-2 Omicron sub-lineages elicited by pre-Omicron or Omicron breakthrough infection with exposure interval compensation modeling
2023· 1 citedOpen Access
Specific COVID-19 risk behaviors and the preventive effect of personal protective equipment among healthcare workers in Japan
Global Health & Medicine·2023· 3 citedOpen Access
Non-Omicron breakthrough infection with higher viral load and longer vaccination-infection interval improves SARS-CoV-2 BA.4/5 neutralization
iScience·2023· 15 citedOpen Access
Results from a preclinical study in rodents and a Phase 1/2, randomized, double-blind, placebo-controlled, parallel-group study of COVID-19 vaccine S-268019-a in Japanese adults
Vaccine·2022· 4 citedOpen Access
Immune response and protective efficacy of the SARS-CoV-2 recombinant spike protein vaccine S-268019-b in mice
Scientific Reports·2022· 6 citedOpen Access
Histological characteristics of matrix metalloproteinase‐9 and tissue inhibitor of metalloproteinases‐1 in asthmatic murine model during A(H1N1)pdm09 infection
Pathology International·2022· 3 cited
Intranasal vaccination induced cross-protective secretory IgA antibodies against SARS-CoV-2 variants with reducing the potential risk of lung eosinophilic immunopathology
Vaccine·2022· 21 citedOpen Access
Viral load and timing of infection define neutralization diversity to SARS-CoV-2 infection
2022Open Access
Intranasal vaccination induced cross-protective secretory IgA antibodies against SARS-CoV-2 variants with reducing the potential risk of lung eosinophilic immunopathology
2022· 2 citedOpen Access
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Frequent Co-authors

Hideki Hasegawa(44), Tadaki Suzuki(30), Masato Tashiro(13), Shinichi Tamura(10), Takato Odagiri(9), Minoru Tobiume(8), Tetsutaro Sata(8), Takayuki Kanno(8), Shô Miyamoto(8), Takeshi Kurata(7), Noriyo Nagata(7), Kaori Sano(7), Harutaka Katano(6), Naoko Iwata‐Yoshikawa(6), Shinji Saito(5), Takeshi Arashiro(5), Shun Iida(5), Takuya Hemmi(5), Akira Ueno(5), Yoshimasa Takahashi(5)