Lunfeng Zhang

University of California, San Diego — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

16h-index752citations32works0.02yr avg
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Research Topics

PI3K/AKT/mTOR signaling in cancer(10), Biochemical and Molecular Research(6), Cardiomyopathy and Myosin Studies(5), Congenital heart defects research(5), Protein Tyrosine Phosphatases(4)

Publications32 total

Adventitial leptin receptor-expressing fibroblasts are preferential contributors to fibrotic remodeling of the heart post infarction
2025Open Access
Abstract 4061: Preclinical characterization of MBS309, a conditionally active PD-1-dependent IL-2 mutation with significantly superior anti-tumor efficacy with safety
Cancer Research·2024
Supplementary methods from PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells
2023Open Access
Data from PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells
2023Open Access
Data from PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells
2023Open Access
Supplementary figures from PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells
2023Open Access
Supplementary figures from PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells
2023Open Access
Supplementary tables from PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells
2023Open Access
Supplementary methods from PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells
2023Open Access
Supplementary tables from PI-273, a Substrate-Competitive, Specific Small-Molecule Inhibitor of PI4KIIα, Inhibits the Growth of Breast Cancer Cells
2023Open Access
RNA binding protein DDX5 restricts RORγt <sup>+</sup> T <sub>reg</sub> suppressor function to promote intestine inflammation
Science Advances·2023· 15 citedOpen Access
Filamin C is Essential for mammalian myocardial integrity
PLoS Genetics·2023· 16 citedOpen Access
Increasing Mononuclear Diploid Cardiomyocytes by Loss of E2F Transcription Factor 7/8 Fails to Improve Cardiac Regeneration After Infarct
Circulation·2023· 16 citedOpen Access
DOT1L regulates chamber-specific transcriptional networks during cardiogenesis and mediates postnatal cell cycle withdrawal
Nature Communications·2022· 27 citedOpen Access
The epigenetic modifier DOT1L regulates gene regulatory networks necessary for cardiac patterning and cardiomyocyte cell cycle withdrawal
2022Open Access
In-situ investigation of deformation behavior in additively manufactured FeCoCrNiMn high entropy alloy
Materials Science and Engineering A·2022· 27 cited
Mediator complex proximal Tail subunit MED30 is critical for Mediator core stability and cardiomyocyte transcriptional network
PLoS Genetics·2021· 14 citedOpen Access
Homozygous G650del nexilin variant causes cardiomyopathy in mice
JCI Insight·2020· 23 citedOpen Access
Nexilin Is Necessary for Maintaining the Transverse-Axial Tubular System in Adult Cardiomyocytes
Circulation Heart Failure·2020· 35 citedOpen Access
Atypical ALPK2 kinase is not essential for cardiac development and function
American Journal of Physiology-Heart and Circulatory Physiology·2020· 9 citedOpen Access
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Frequent Co-authors

Sylvia Μ. Evans(15), Ju Chen(12), Jiangmei Li(12), Chang Chen(12), Xinhua Qiao(11), Hualiang Jiang(9), Yingying Zhao(8), Zhen Gao(8), Dan Zhao(8), Hong Ding(8), Junyan Lu(8), Cheng Luo(8), Paola Cattaneo(7), Nuno Guimarães‐Camboa(7), Panpan Zhang(7), Simone Spinozzi(6), Julius Bogomolovas(6), Jia Liu(6), Yusu Gu(5), Ze’e Chen(5)