Laurence Tropia

University of Geneva — Switzerland

Biochemistry, Genetics and Molecular Biology · Life Sciences

6h-index326citations15works1.02yr avg
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Research Topics

Epigenetics and DNA Methylation(4), Cancer-related Molecular Pathways(4), DNA Repair Mechanisms(3), Food Allergy and Anaphylaxis Research(3), Asthma and respiratory diseases(2)

Publications15 total

Human POLD3 coordinates leading and lagging strand in Mitotic DNA Synthesis
2025Open Access
REV7 functions with REV3 as a checkpoint protein delaying mitotic entry until DNA replication is completed
Cell Reports·2025· 2 citedOpen Access
Non-covalent SARS-CoV-2 Mpro inhibitors developed from in silico screen hits
Scientific Reports·2022· 65 citedOpen Access
Identification of low micromolar SARS-CoV-2 M <sup>pro</sup> inhibitors from hits identified by <i>in silico</i> screens
2020· 3 citedOpen Access
Crystal structure of mammalian Rev7 in complex with human Chromosome alignment-maintaining phosphoprotein 1
2017
Crystal structure of mammalian Rev7 in complex with Rev3 1875-1895
2017
Reversal of the DNA-Binding-Induced Loop L1 Conformational Switch in an Engineered Human p53 Protein
Journal of Molecular Biology·2014· 47 citedOpen Access
Crystal structure of a polypeptide p53 mutant bound to DNA
2013
Crystal structure of a human mutant p53
2013· 1 cited
A high resolution genomic portrait of bladder cancer: correlation between genomic aberrations and the DNA damage response
Oncogene·2012· 41 cited
Abstract 3109: Correlation between genomic aberrations and the DNA damage response in bladder cancer
Cancer Research·2012
Crystal Structure of a Multidomain Human p53 Tetramer Bound to the Natural <i>CDKN1A</i> (<i>p21</i>) p53-Response Element
Molecular Cancer Research·2011· 57 cited
Lymphocytes in Peyer patches regulate clinical tolerance in a murine model of food allergy
Journal of Allergy and Clinical Immunology·2004· 72 cited
1L-10 induces antigen-specific T-cell anergy but no regulatory T cells in children with Egg allergy
Journal of Allergy and Clinical Immunology·2003· 1 citedOpen Access
The mucosal adhesion receptor α4β7 integrin is selectively increased in lymphocytes stimulated with β-lactoglobulin in children allergic to cow’s milk
Journal of Allergy and Clinical Immunology·1999· 37 cited

Frequent Co-authors

Thanos D. Halazonetis(12), Soheila Emamzadah(7), Philippe Eigenmann(3), Vasilis S. Dionellis(3), Ilena Vincenti(3), Benoît Falquet(3), Conrad Hauser(2), Giacomo Rossetti(2), Marianna Ossorio(2), Samia Barriot(2), Christoph Gorgulla(2), Haribabu Arthanari(2), Peter J. Mohr(2), Remo Gamboni(2), Troels Schepeler(2), Philippe Lamy(2), Jens R. Laurberg(2), Niels Fristrup(2), Thomas Reinert(2), Jiřina Bártková(2)