Wayne M. Clark

Oregon Health & Science University — United States

Medicine · Health Sciences

64h-index25.0kcitations195works30.72yr avg
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Research Topics

Acute Ischemic Stroke Management(105), Cerebrovascular and Carotid Artery Diseases(74), Intracranial Aneurysms: Treatment and Complications(27), Neuroinflammation and Neurodegeneration Mechanisms(23), Neurological Disorders and Treatments(22)

Publications188 total

Medical Management and Revascularization for Asymptomatic Carotid Stenosis
New England Journal of Medicine·2025· 18 cited
Abstract 256: Post Hoc Analysis of RESCUE Trial Shows Shortened Hospital Stay and Higher Rate of Discharge to Home in Participants Treated with RNS60
Stroke Vascular and Interventional Neurology·2025Open Access
Randomized, Proof-of-Concept Trial (RESCUE) of RNS60 as an Adjunct Therapy in Acute Ischemic Stroke
Stroke·2025· 3 cited
O-057 Post hoc analysis of rescue shows improvement in all prespecified efficacy endpoints in participants enrolled <12h since symptom onset
2025
RESCUE: A Proof-of-Concept Trial with Adjunct RNS60 Treatment Shows Safety, Reduced Infarct Growth, and Numerical Improvement in all Prespecified Efficacy Endpoints in Participants with Acute Ischemic Stroke (S25.007)
Neurology·2025
Development of a machine learning model to predict changes in neuroimaging profiles among acute ischemic stroke patients following delayed transfer for endovascular thrombectomy
Neuroradiology·2025· 1 cited
Abstract WP3: Large Vessel Recanalization with Thrombolysis Prior to Thrombectomy: Incidence, Outcomes, and Associations With Collateral Status
Stroke·2025Open Access
Abstract TP233: Machine Learning Model to Predict Changes in Neuroimaging Profiles Following Delayed Transfer for Stroke Thrombectomy
Stroke·2025
Abstract 7: RESCUE: Proof of Concept Trial With RNS60 Shows Safety, Reduced Infarct Growth, and Numerical Improvement in all Prespecified Efficacy Endpoints in Subjects With Ischemic Stroke Receiving Mechanical Thrombectomy
Stroke·2025
The PANDA score: External validation and modification of a simple upfront prediction tool for poor outcomes despite successful stroke thrombectomy
Clinical Neurology and Neurosurgery·2025· 3 cited
O-030 The panda score: modification and external validation of a simple upfront prediction tool for poor outcomes despite successful stroke thrombectomy
2024Open Access
HEMERA 1 Carboxy <u>HEM</u> oglobin oxyg <u>E</u> n delivery for <u>R</u> evascularization in <u>A</u> cute Stroke: A Prospective, Randomized Phase 1 Clinical Trial
Stroke Vascular and Interventional Neurology·2024· 4 citedOpen Access
RESCUE: A Randomized, Blinded, Placebo-controlled, Parallel Group Study Design to Determine the Safety of RNS60 in Large Vessel Occlusion Stroke Patients Undergoing Endovascular Thrombectomy (P10-5.029)
Neurology·2024
Tenecteplase for Stroke at 4.5 to 24 Hours with Perfusion-Imaging Selection
New England Journal of Medicine·2024· 154 cited
Apixaban to Prevent Recurrence After Cryptogenic Stroke in Patients With Atrial Cardiopathy
JAMA·2024· 161 citedOpen Access
Thrombectomy With the pRESET vs Solitaire Stent Retrievers as First-Line Large Vessel Occlusion Stroke Treatment
JAMA Neurology·2024· 17 citedOpen Access
Low body mass index patients have worse outcomes after mechanical thrombectomy
Journal of NeuroInterventional Surgery·2023· 2 cited
Differential effect of gold nanoparticles on cerebrovascular function and biomechanical properties
Physiological Reports·2023· 3 citedOpen Access
LB-005 Hemera 1 carboxyhemoglobin oxygendelivery for revascularization in acute stroke: a prospective, randomized phase 1 clinical trial
2023Open Access
Abstract Number ‐ 8: HEMERA 1 CarboxyHEMoglobin OxygEn delivery for Revascularization in Acute Stroke: Phase 1 Clinical Trial
Stroke Vascular and Interventional Neurology·2023· 1 citedOpen Access
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Frequent Co-authors

Gregory W. Albers(7), Bruce M. Coull(7), Michael D. Hill(6), Nikola Lessov(6), Frank L. Silver(5), Thomas G. Brott(5), George Howard(5), Joseph P. Broderick(5), Tudor G. Jovin(5), Gary M. Nesbit(5), Stanley L. Barnwell(5), William H. Brooks(4), Ariane Mackey(4), James F. Meschia(4), Osama O. Zaidat(4), Jeffrey L. Saver(4), Kenneth P. Madden(4), Scott Hamilton(4), L. Creed Pettigrew(4), Lawrence R. Wechsler(3)