Ahmed Rattani

Beth Israel Deaconess Medical Center — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

9h-index428citations29works0.62yr avg
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Research Topics

Microtubule and mitosis dynamics(11), Genomics and Chromatin Dynamics(6), DNA Repair Mechanisms(4), Pancreatic and Hepatic Oncology Research(4), Reproductive Biology and Fertility(3)

Publications29 total

A phase 2 study of botensilimab and AGEN1423, an anti-CD73-TGFβ-trap bifunctional antibody, in subjects with advanced pancreatic cancer.
Journal of Clinical Oncology·2026
The Wnt/APC destruction complex targets SREBP2 in a β-catenin-independent pathway to control cholesterol metabolism
2025Open Access
POSTER: TCL-888 Enteropathy-Associated T-Cell Lymphoma in the United States: A Population-Based SEER Analysis (2000–2021)
Clinical Lymphoma Myeloma & Leukemia·2025
TCL-888: Enteropathy-Associated T-Cell Lymphoma in the United States: A Population-Based SEER Analysis (2000–2021)
Clinical Lymphoma Myeloma & Leukemia·2025
Prognostic Role of <i>MTAP</i> Loss in Cholangiocarcinoma
JCO Precision Oncology·2025· 3 citedOpen Access
A Phase 2 Trial of Niraparib in Patients with Advanced Pancreatic Cancer Harboring Pathogenic Variants in ATM, BRCA1, BRCA2, PALB2, and CHEK2
Clinical Cancer Research·2025
Abstract PR-04: Phase 2 Trial Testing The PARP Inhibitor Niraparib In Patients With Advanced Pancreatic Cancer with Pathogenic Variants In <i>BRCA 1, BRCA2, PALB2, ATM</i> and <i>CHEK2</i>
Cancer Research·2024
Abstract A001: An open label, phase II trial of ERK inhibition alone and in combination with autophagy inhibition in patients with metastatic cancreatic cancer
Cancer Research·2024· 3 cited
Somatic Mutation Profile as a Predictor of Treatment Response and Survival in Unresectable Pancreatic Ductal Adenocarcinoma Treated with FOLFIRINOX and Gemcitabine Nab-Paclitaxel
Cancers·2024Open Access
Association between somatic mutation pathways and treatment response in patients with biliary tract cancers (BTCs).
Journal of Clinical Oncology·2024
More on Anti–Insulin Receptor Antibody in Malignant Insulinoma and Refractory Hypoglycemia
New England Journal of Medicine·2023
FRI603 Treatment Of Severe Refractory Hypoglycemia Due To Malignant Insulinoma With A Novel Anti-insulin Receptor Antibody
Journal of the Endocrine Society·2023· 1 citedOpen Access
Anti–Insulin Receptor Antibody for Malignant Insulinoma and Refractory Hypoglycemia
New England Journal of Medicine·2023· 9 citedOpen Access
Molecular profiling as a predictor of treatment response and survival in unresectable pancreatic ductal adenocarcinoma.
Journal of Clinical Oncology·2023
Loss of sister kinetochore co-orientation and peri-centromeric cohesin protection after meiosis I depends on cleavage of centromeric REC8
Developmental Cell·2021· 34 citedOpen Access
Loss of Sister Kinetochore Co-orientation and Peri-centromeric Cohesin Protection after Meiosis I Depends on Cleavage of Centromeric REC8
2020· 6 citedOpen Access
Machine learning-based prediction of response to PARP inhibition across cancer types
2019· 3 citedOpen Access
An imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets
Journal of Hematology & Oncology·2017· 42 citedOpen Access
APC/CCdh1 Enables Removal of Shugoshin-2 from the Arms of Bivalent Chromosomes by Moderating Cyclin-Dependent Kinase Activity
Current Biology·2017· 11 citedOpen Access
Additional file 3: of An imprinted non-coding genomic cluster at 14q32 defines clinically relevant molecular subtypes in osteosarcoma across multiple independent datasets
Figshare·2017Open Access
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Frequent Co-authors

Kim Nasmyth(9), Jonathan Godwin(8), Mary Linton B. Peters(6), Soravis Osataphan(5), Magda Wolna(4), Alberto M. Pendás(4), Sugako Ogushi(4), Rodrigo Paredes(4), Olaf Stemmann(3), Marcos Malumbres(3), Béla Novák(3), Mary Herbert(3), Katherine E. Hill(3), Andrew D. Kelly(3), Cassandra C. Garbutt(3), Edwin Choy(3), Benjamin Haibe‐Kains(3), Dimitrios Spentzos(3), Jean Metson(3), Mary‐Elizabeth Patti(3)