Ching Tung Lum

University of Hong Kong — Hong Kong

Medicine · Health Sciences

21h-index2.4kcitations25works0.02yr avg
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Research Topics

Metal complexes synthesis and properties(9), Advanced biosensing and bioanalysis techniques(3), Ubiquitin and proteasome pathways(3), Click Chemistry and Applications(3), N-Heterocyclic Carbenes in Organic and Inorganic Chemistry(3)

Publications25 total

Shotgun Proteomics and Quantitative Pathway Analysis of the Mechanisms of Action of Dehydroeffusol, a Bioactive Phytochemical with Anticancer Activity from <i>Juncus effusus</i>
Journal of Proteome Research·2018· 10 cited
ChemInform Abstract: Chemical Biology of Anticancer Gold(III) and Gold(I) Complexes
ChemInform·2016
Alkynyl gold(I) phosphane complexes: Evaluation of structure–activity-relationships for the phosphane ligands, effects on key signaling proteins and preliminary in-vivo studies with a nanoformulated complex
Journal of Inorganic Biochemistry·2015· 59 citedOpen Access
IFITM1 promotes the metastasis of human colorectal cancer via CAV-1
Cancer Letters·2015· 81 cited
Chemical biology of anticancer gold(<scp>iii</scp>) and gold(<scp>i</scp>) complexes
Chemical Society Reviews·2015· 607 cited
Luminescent Cyclometalated Platinum(II) Complex Forms Emissive Intercalating Adducts with Double‐Stranded DNA and RNA: Differential Emissions and Anticancer Activities
Angewandte Chemie·2014· 31 cited
Luminescent Cyclometalated Platinum(II) Complex Forms Emissive Intercalating Adducts with Double‐Stranded DNA and RNA: Differential Emissions and Anticancer Activities
Angewandte Chemie International Edition·2014· 95 cited
A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N‐Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo
Angewandte Chemie·2014· 30 cited
A Binuclear Gold(I) Complex with Mixed Bridging Diphosphine and Bis(N‐Heterocyclic Carbene) Ligands Shows Favorable Thiol Reactivity and Inhibits Tumor Growth and Angiogenesis In Vivo
Angewandte Chemie International Edition·2014· 147 cited
Gold(iii) complexes inhibit growth of cisplatin-resistant ovarian cancer in association with upregulation of proapoptotic PMS2 gene
Chemical Science·2014· 65 cited
Gold(III) Complexes Containing N‐Heterocyclic Carbene Ligands: Thiol “Switch‐on” Fluorescent Probes and Anti‐Cancer Agents
Angewandte Chemie·2013· 54 cited
Gold(III) Complexes Containing N‐Heterocyclic Carbene Ligands: Thiol “Switch‐on” Fluorescent Probes and Anti‐Cancer Agents
Angewandte Chemie International Edition·2013· 218 cited
A gold(<scp>iii</scp>) porphyrin complex as an anti-cancer candidate to inhibit growth of cancer-stem cells
Chemical Communications·2012· 65 cited
Gold(III) porphyrin 1a prolongs the survival of melanoma-bearing mice and inhibits angiogenesis
Acta Oncologica·2010· 34 citedOpen Access
Gold(III) porphyrin 1a inhibited nasopharyngeal carcinoma metastasis in vivo and inhibited cell migration and invasion in vitro
Cancer Letters·2010· 44 cited
Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric cancer
International Journal of Cancer·2009· 40 cited
Specific inhibitors of the protein tyrosine phosphatase Shp2 identified by high-throughput docking
Proceedings of the National Academy of Sciences·2008· 221 citedOpen Access
Gold(III) compound is a novel chemocytotoxic agent for hepatocellular carcinoma
International Journal of Cancer·2005· 79 citedOpen Access
Allograft inflammatory factor-1 (AIF-1) is crucial for the survival and pro-inflammatory activity of macrophages
International Immunology·2005· 138 citedOpen Access
Identification of Brain-Derived Neurotrophic Factor as a Novel Functional Protein in Hepatocellular Carcinoma
Cancer Research·2005· 91 citedOpen Access
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Frequent Co-authors

Chi‐Ming Che(15), Taotao Zou(10), Chun‐Nam Lok(7), Marie C.M. Lin(6), Hsiang Fu Kung(5), Zhen Yang(3), Ronnie T.P. Poon(3), Sheung Tat Fan(3), Raymond Wai‐Yin Sun(3), Stephen Sin‐Yin Chui(2), Shui Ping Tu(2), Xiao Jiang(2), Yi Yang(2), Shi Hu Jiang(2), Benjamin Chun–Yu Wong(2), Wai‐Pong To(2), Kam‐Hung Low(2), David Ho(2), Chi Tat Lam(2), Chensheng Ma(2)