Ina Oehme

German Cancer Research Center — Germany

Biochemistry, Genetics and Molecular Biology · Life Sciences

38h-index5.4kcitations201works1.92yr avg
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Research Topics

Histone Deacetylase Inhibitors Research(96), Protein Degradation and Inhibitors(71), Glioma Diagnosis and Treatment(63), Epigenetics and DNA Methylation(42), Neuroblastoma Research and Treatments(36)

Publications201 total

Systematic functional drug testing in patient-derived models reveals ex vivo sensitivities associated with clinical outcome in rare solid tumors
2026Open Access
Intratumor heterogeneity and clonal evolution in sarcomas: Molecular, cellular, and functional drivers of therapy resistance
Seminars in Cancer Biology·2026Open Access
Supplementary Figure S1 from Integrative Multiomics and Drug Sensitivity Profiling Reveal Potential Biomarkers and Therapeutic Strategies in Pediatric Solid Tumors
2026Open Access
Integrative Multiomics and Drug Sensitivity Profiling Reveal Potential Biomarkers and Therapeutic Strategies in Pediatric Solid Tumors
Cancer Research·2025Open Access
Remission instead of eradication? MEK inhibition in primary refractory childhood LCH
Blood·2025
Identifizierung eines Moleküls, das den Abbau der aktivierten Checkpoint‐Kinase‐1 auslöst und Charakterisierung der nicht‐katalytischen Funktionen von Checkpoint‐Kinase‐1 in Tumorzellen
Angewandte Chemie·2025Open Access
Identification of a Proteolysis‐Targeting‐Chimera that Addresses Activated Checkpoint Kinase‐1 Reveals its Non‐Catalytic Functions in Tumor Cells
Angewandte Chemie International Edition·2025Open Access
High 4E-BP1 expression associates with chromosome 8 gain and CDK4/6 sensitivity in Ewing sarcoma
Journal of Clinical Investigation·2025Open Access
New cell lines expanding the diversity of Ewing sarcoma models
International Journal of Cancer·2025Open Access
High content-imaging drug synergy screening identifies specific senescence-related vulnerabilities of mesenchymal neuroblastomas
Cell Death and Disease·2025· 2 citedOpen Access
Rapid proteasomal degradation of mutant feline McDonough sarcoma-like tyrosine kinase-3 overcomes inhibitor resistance mechanisms of acute myeloid leukemia cells
2025Open Access
Phenotypic plasticity in a novel set of <scp>EGFR</scp> tyrosine kinase inhibitor‐adapted non‐small cell lung cancer cell lines
FEBS Open Bio·2025· 1 citedOpen Access
Rapid proteasomal degradation of mutant feline McDonough sarcoma-like tyrosine kinase-3 overcomes tyrosine kinase inhibitor resistance of acute myeloid leukemia cells
2025· 1 citedOpen Access
Somatic gene delivery faithfully recapitulates a molecular spectrum of high-risk sarcomas
Nature Communications·2025· 4 citedOpen Access
Development of a ROS- and lysosome-addressing combination treatment for relapsed Neuroblastoma
Klinische Pädiatrie·2025
Clinical evaluation of ex vivo drug sensitivity profiling in the pediatric precision oncology program INFORM
Klinische Pädiatrie·2025
The protein deacetylase HDAC10 controls DNA replication in malignant lymphoid cells
Leukemia·2025· 5 citedOpen Access
Abstract A013: Functional profiling in pediatric precision medicine: global collaboration to drive clinical implementation
Cancer Research·2025
Abstract B006: Employing fresh tumor samples and long-term cultures for personalized drug response profiling in childhood solid cancers
Cancer Research·2025
Exploring high-throughput drug sensitivity testing in neuroblastoma cell lines and patient-derived tumor organoids in the era of precision medicine
European Journal of Cancer·2025· 9 citedOpen Access
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Frequent Co-authors

Olaf Witt(37), Till Milde(26), Hedwig E. Deubzer(17), Johannes Ridinger(14), Stefan M. Pfister(13), Andreas von Deimling(12), Marco Lodrini(12), Andrey Korshunov(10), Heike Peterziel(10), Frank Westermann(9), Manfred Jung(9), Wolfgang Sippl(8), Marcel Kool(7), Andreas E. Kulozik(7), Florian Selt(7), David Jones(7), Annette Kopp‐Schneider(6), Olaf Witt(6), E Koeneke(6), Thomas Hielscher(6)