Sophie Desmots

Institut national de l'environnement industriel et des risques — France

Agricultural and Biological Sciences · Life Sciences

11h-index383citations34works0.02yr avg
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Research Topics

Pesticide Exposure and Toxicity(7), Sperm and Testicular Function(5), Toxic Organic Pollutants Impact(5), Effects and risks of endocrine disrupting chemicals(5), Carcinogens and Genotoxicity Assessment(4)

Publications34 total

Evaluation of Placental Transfer and Tissue Distribution of cis- and Trans-Permethrin in Pregnant Rats and Fetuses Using a Physiological-Based Pharmacokinetic Model
Frontiers in Pediatrics·2021· 14 citedOpen Access
PBPK modeling of the cis- and trans-permethrin isomers and their major urinary metabolites in rats
Toxicology and Applied Pharmacology·2016· 31 citedOpen Access
Multivariate associations between (i) variables related to <i>in utero</i> exposure to pesticides, (ii) birth length (BL, in cm) and low birth length) (continued).
Figshare·2015Open Access
Self-Reported Parental Exposure to Pesticide during Pregnancy and Birth Outcomes: The MecoExpo Cohort Study
PLoS ONE·2014· 22 citedOpen Access
Determination of cis-permethrin, trans-permethrin and associated metabolites in rat blood and organs by gas chromatography–ion trap mass spectrometry
Analytical and Bioanalytical Chemistry·2014· 25 citedOpen Access
Development of a toxicokinetic model in rat of the cis and trans-permethrin and theirs three metabolites.
HAL (Le Centre pour la Communication Scientifique Directe)·2013
Elaboration d'un modèle toxicocinétique de la cis et trans-perméthrine et de ses métabolites chez le rat
HAL (Le Centre pour la Communication Scientifique Directe)·2013
Prediction of dose-hepatotoxic response in humans based on toxicokinetic/toxicodynamic modeling with or without in vivo data: A case study with acetaminophen
Toxicology Letters·2013· 34 citedOpen Access
A comparison of two human cell lines and two rat gonadal cell primary cultures as in vitro screening tools for aromatase modulation
Toxicology in Vitro·2011· 32 cited
Aryl hydrocarbon receptor-dependent induction of the IgA receptor FcαRI by the environmental contaminant benzo(a)pyrene in human macrophages
Toxicology·2011· 8 cited
Endocrine disruption and steroidogenesis : integrated evaluation from gonadal steroidogenic enzymes in vitro and in vivo to hormonal balance and fertility assessment in vivo
HAL (Le Centre pour la Communication Scientifique Directe)·2011
Aryl hydrocarbon receptor-dependent induction of the IgA receptor FcalphaRI by the environmental contaminant benzo(a)pyrene in human macrophages
Toxicology Letters·2011· 3 cited
Effects of endocrine disruptors in adult rats: integrative evaluation from gonadal steroidogenic gene expression profiles to hormonal balance
HAL (Le Centre pour la Communication Scientifique Directe)·2011
Predicting in vivo gene expression in macrophages after exposure to benzo(a)pyrene based on in vitro assays and toxicokinetic/toxicodynamic models
Toxicology Letters·2010· 13 cited
Apports des approches " omiques " pour modéliser la cinétique et les effets de xénobiotiques chez l'homme
HAL (Le Centre pour la Communication Scientifique Directe)·2010
Endocrine disruptors and steroidogenesis : integrative evaluation
HAL (Le Centre pour la Communication Scientifique Directe)·2010
The in vitro blood-testis-barrier : a new promising alternative for reproductive toxicity studies
HAL (Le Centre pour la Communication Scientifique Directe)·2010
Développement d'un modèle de barrière hemato-testiculaire (BHT) in vitro pour l'évaluation des reprotoxiques
HAL (Le Centre pour la Communication Scientifique Directe)·2010
Identification de nouveaux gènes cibles des hydrocarbures aromatiques polycycliques dans les macrophages humains en culture primaire par une approche transcriptomique
HAL (Le Centre pour la Communication Scientifique Directe)·2010
Un modèle de barrière hémato-testiculaire in vitro pour l'évaluation de la reprotoxicité chez le mâle
HAL (Le Centre pour la Communication Scientifique Directe)·2010
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Frequent Co-authors

Emmanuel Lemazurier(14), Lydie Sparfel(10), Olivier Fardel(9), Céline Brochot(9), Anthony Lecomte(9), Marie‐Laure Pinel‐Marie(7), Audrey Legendre(7), Robert Barouki(7), René Habert(6), Nadia Quignot(6), Franck Robidel(6), Magali Boize(5), A. Pery(5), Pascal Froment(5), Florence Zeman(5), Serge Koscielny(4), François Lestremau(4), Alexandre R.R. Péry(3), Marie‐Emilie Willemin(3), R. Le Grand(3)