Masataka Shiozuka

Kyushu University Hospital — Japan

Biochemistry, Genetics and Molecular Biology · Life Sciences

15h-index603citations35works0.02yr avg
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Research Topics

Muscle Physiology and Disorders(13), RNA and protein synthesis mechanisms(6), Antimicrobial Peptides and Activities(4), Adipose Tissue and Metabolism(4), Cancer therapeutics and mechanisms(4)

Publications34 total

Academia–industry Cooperation in the Medical Field: Matching Opportunities in Japan
Clinical Therapeutics·2018· 15 cited
Pharmacological targeting of HSP90 with 17-AAG induces apoptosis of myogenic cells through activation of the intrinsic pathway
Molecular and Cellular Biochemistry·2017· 14 cited
Structure–Activity Relationship Study of Leucyl-3-<i>epi</i>-deoxynegamycin for Potent Premature Termination Codon Readthrough
ACS Medicinal Chemistry Letters·2017· 13 citedOpen Access
Effects of ageing on expression of the muscle-specific E3 ubiquitin ligases and Akt-dependent regulation of Foxo transcription factors in skeletal muscle
Molecular and Cellular Biochemistry·2015· 26 cited
Zinc promotes proliferation and activation of myogenic cells via the PI3K/Akt and ERK signaling cascade
Experimental Cell Research·2015· 112 cited
Negamycin Interferes with Decoding and Translocation by Simultaneous Interaction with rRNA and tRNA
Molecular Cell·2014· 53 citedOpen Access
Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites
2014
Crystal structure of the Thermus thermophilus 70S ribosome in complex with negamycin, mRNA and three deacylated tRNAs in the A, P and E sites
2014
Dietary Phosphorus Overload Aggravates the Phenotype of the Dystrophin-Deficient mdx Mouse
American Journal Of Pathology·2014· 16 citedOpen Access
Discovery of Natural Products Possessing Selective Eukaryotic Readthrough Activity: 3‐<i>epi</i>‐Deoxynegamycin and Its Leucine Adduct
ChemMedChem·2014· 25 cited
Sphingosine-1-phosphate mediates epidermal growth factor-induced muscle satellite cell activation
Experimental Cell Research·2014· 22 cited
Transdermal Delivery of Adriamycin to Transplanted Ehrlich Ascites Tumor in Mice
Pharmaceutics·2013· 2 citedOpen Access
Structure Activity Relationship Study of Dipeptide Antibiotic (+)-Negamycin for the Potent Readthrough Promoting Activity
Peptide science : proceedings of the ... Japanese Peptide Symposium·2013
Development of (+)-Negamycin Derivatives with Potent Readthrough Activity for Duchenne Muscular Dystrophy Chemotherapy
Peptide science : proceedings of the ... Japanese Peptide Symposium·2012
Negamycin Analogue with Readthrough-Promoting Activity as a Potential Drug Candidate for Duchenne Muscular Dystrophy
ACS Medicinal Chemistry Letters·2012· 24 cited
[Therapeutic readthrough strategy for suppression of nonsense mutations in duchenne muscular dystrophy].
PubMed·2011· 1 cited
Pharmacological inhibition of HSP90 activity negatively modulates myogenic differentiation and cell survival in C2C12 cells
Molecular and Cellular Biochemistry·2011· 29 cited
Synthesis and Biological Evaluation of Dipeptidic Antibiotics (+)-Negamycin and Its Derivatives for Development of Duchenne Muscular Dystrophy Chemotherapy
Peptide science : proceedings of the ... Japanese Peptide Symposium·2011
Mitochondrial adaptations in skeletal muscle to hindlimb unloading
Molecular and Cellular Biochemistry·2010· 68 cited
Transdermal delivery of a readthrough-inducing drug: a new approach of gentamicin administration for the treatment of nonsense mutation-mediated disorders
The Journal of Biochemistry·2009· 21 cited
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Frequent Co-authors

Ryoichi Matsuda(23), Yoshio Hayashi(8), Akihiro Taguchi(6), Masayuki Arakawa(5), Fumika Yakushiji(5), Yoshiaki Nonomura(5), Yosuke Nagata(4), Yoshiaki Kiso(4), Yuri Yamazaki(4), Ichirô KIMURA(4), Kazuya Ohashi(3), E. Wada(3), Akira Wagatsuma(3), Shigeru Yamada(3), Yury S. Polikanov(3), Pulkit Gupta(3), Thomas A. Steitz(3), Nora Vázquez‐Laslop(3), Kunihiko Mabuchi(3), Keisuke Hamada(3)