Brady J. Maher

Johns Hopkins University — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

27h-index4.9kcitations75works1.62yr avg
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Research Topics

Genetics and Neurodevelopmental Disorders(26), Neuroscience and Neuropharmacology Research(14), Congenital heart defects research(11), Pluripotent Stem Cells Research(10), Neurogenesis and neuroplasticity mechanisms(10)

Publications75 total

M52. INDUCED PLURIPOTENT STEM CELL-DERIVED TROPHOBLAST, A NON-BRAIN MODEL, TO UNCOVER CAUSATIVE MECHANISMS FOR SCHIZOPHRENIA
European Neuropsychopharmacology·2025
Myelination across the autism spectrum: therapeutic targeting of the oligodendrocyte lineage and myelination defects
Neuropsychopharmacology·2025
Generation of induced pluripotent stem cells from 8 neurotypical individuals with elevated genetic risk for schizophrenia
Stem Cell Research·2025Open Access
Characterization of astrocyte density in the Pitt-Hopkins Syndrome mouse model of ASD
2025Open Access
Intersectin and endophilin condensates prime synaptic vesicles for release site replenishment
Nature Neuroscience·2025· 3 citedOpen Access
Automated high-throughput patch clamp electrophysiology of hiPSC-derived neuronal models
2025· 1 citedOpen Access
Transcriptomics and proteomics of projection neurons in a circuit linking hippocampus with dorsolateral prefrontal cortex in the human brain
2024Open Access
Utilizing hiPSC-derived oligodendrocytes to study myelin pathophysiology in neuropsychiatric and neurodegenerative disorders.
Frontiers in Cellular Neuroscience·2024· 9 citedOpen Access
Psychiatric risk gene Transcription Factor 4 (TCF4) regulates the density and connectivity of distinct inhibitory interneuron subtypes
Molecular Psychiatry·2023· 13 citedOpen Access
TCF4 Mutations Disrupt Synaptic Function Through Dysregulation of RIMBP2 in Patient-Derived Cortical Neurons
Biological Psychiatry·2023· 17 citedOpen Access
Promyelinating drugs promote functional recovery in an autism spectrum disorder mouse model of Pitt–Hopkins syndrome
Brain·2023· 34 citedOpen Access
Consensus molecular environment of schizophrenia risk genes in coexpression networks shifting across age and brain regions
Science Advances·2023· 21 citedOpen Access
302. Investigating the Impact of Common Genetic Risk Variants for Schizophrenia on Neuronal Function Elucidates Relationships Between Cellular Phenotypes, Clinical Status and Cognitive Performance
Biological Psychiatry·2023
301. Pro-Myelinating Drugs Promote Functional Recovery in an ASD Mouse Model of Pitt-Hopkins Syndrome
Biological Psychiatry·2023
TCF4 mutations disrupt synaptic function through dysregulation of RIMBP2 in patient-derived cortical neurons
2023· 3 citedOpen Access
A Missense Variant in CASKIN1’s Proline-Rich Region Segregates with Psychosis in a Three-Generation Family
Genes·2023· 4 citedOpen Access
CaPTure: Calcium PeakToolbox for analysis of in vitro calcium imaging data
BMC Neuroscience·2022· 9 citedOpen Access
Evaluation of Nav1.8 as a therapeutic target for Pitt Hopkins Syndrome
Molecular Psychiatry·2022· 16 citedOpen Access
Anterior Insula–Associated Social Novelty Recognition: Pivotal Roles of a Local Retinoic Acid Cascade and Oxytocin Signaling
American Journal of Psychiatry·2022· 17 cited
Clemastine fumarate enhances myelination and promotes functional recovery in a syndromic ASD mouse model of Pitt-Hopkins Syndrome
2022· 1 citedOpen Access
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Frequent Co-authors

Andrew E. Jaffe(16), Srinidhi Rao Sripathy(12), Daniel R. Weinberger(11), Stephanie C. Page(11), Joo Heon Shin(10), Thomas M. Hyde(8), Joel E. Kleinman(8), Matthew D. Rannals(8), Keri Martinowich(7), Joseph F. Bohlen(7), Gregory R. Hamersky(6), Richard E. Straub(6), BaDoi N. Phan(6), Joseph J. LoTurco(6), Ran Tao(5), A.J. Cross(5), Nicholas J. Brandon(5), Yanhong Wang(5), Zengyou Ye(5), Huei-Ying Chen(5)