Fernando Salgado-Polo

The Netherlands Cancer Institute — Netherlands

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index461citations20works0.02yr avg
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Research Topics

Sphingolipid Metabolism and Signaling(17), Endoplasmic Reticulum Stress and Disease(10), Lipid Membrane Structure and Behavior(4), Cellular transport and secretion(4), ATP Synthase and ATPases Research(3)

Publications20 total

Autotaxin facilitates selective LPA receptor signaling
Cell chemical biology·2023· 33 citedOpen Access
A type <scp>IV</scp> Autotaxin inhibitor ameliorates acute liver injury and nonalcoholic steatohepatitis
EMBO Molecular Medicine·2022· 17 citedOpen Access
A type IV Autotaxin inhibitor ameliorates acute liver injury and non-alcoholic steatohepatitis in mice
2022Open Access
Structure-Based Design of a Novel Class of Autotaxin Inhibitors Based on Endogenous Allosteric Modulators
Journal of Medicinal Chemistry·2022· 23 citedOpen Access
Autotaxin facilitates selective LPA receptor signaling
2022· 2 citedOpen Access
Autotaxin Facilitates Selective LPA Receptor Signaling
SSRN Electronic Journal·2022Open Access
Structure and function of the ecto-nucleotide pyrophosphatase/phosphodiesterase (ENPP) family: Tidying up diversity
Journal of Biological Chemistry·2021· 111 citedOpen Access
Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8+ T cells
Cell Reports·2021· 70 citedOpen Access
Imaging Autotaxin <i>In Vivo</i> with <sup>18</sup>F-Labeled Positron Emission Tomography Ligands
Journal of Medicinal Chemistry·2021· 6 citedOpen Access
A novel mechanism of autotaxin-mediated cell signaling that is independent of catalytic activity and inhibited by ziritaxestat
2021
<i>LAHMA</i>: structure analysis through local annotation of homology-matched amino acids
Acta Crystallographica Section D Structural Biology·2020· 6 citedOpen Access
Autotaxin impedes anti-tumor immunity by suppressing chemotaxis and tumor infiltration of CD8 <sup>+</sup> T cells
2020· 5 citedOpen Access
Sequence-dependent trafficking and activity of GDE2, a GPI-specific phospholipase promoting neuronal differentiation
Journal of Cell Science·2020· 14 citedOpen Access
The Structural Binding Mode of the Four Autotaxin Inhibitor Types that Differentially Affect Catalytic and Non-Catalytic Functions
Cancers·2019· 44 citedOpen Access
The potential of different Autotaxin inhibitor types regulating catalysis-dependent and -independent signalling
Preprints.org·2019· 1 citedOpen Access
Sequence-dependent trafficking of GDE2, a GPI-specific phospholipase promoting neuronal differentiation
2019· 1 citedOpen Access
Lysophosphatidic acid produced by autotaxin acts as an allosteric modulator of its catalytic efficiency
Journal of Biological Chemistry·2018· 50 citedOpen Access
Lysophosphatidic acid produced by Autotaxin acts as an allosteric modulator of its catalytic efficiency
2018· 1 citedOpen Access
Rational Design of Autotaxin Inhibitors by Structural Evolution of Endogenous Modulators
Journal of Medicinal Chemistry·2017· 41 citedOpen Access
Structure–Activity Relationships of Small Molecule Autotaxin Inhibitors with a Discrete Binding Mode
Journal of Medicinal Chemistry·2016· 36 citedOpen Access

Frequent Co-authors

Anastassis Perrakis(20), Wouter H. Moolenaar(8), Razvan Borza(5), Craig Jamieson(5), Elisa Matas-Rico(4), Willem‐Jan Keune(4), Paul Ford(4), Bertrand Heckmann(4), Andrew J. Morris(3), Minos–Timotheos Matsoukas(3), Tatjana Heidebrecht(3), Simon J. F. Macdonald(3), Florence Marsais(3), Catherine Jagerschmidt(3), Ludovic Waeckel(3), Elselien Frijlink(2), Irene van der Haar Àvila(2), Apostolos Menegakis(2), Maaike van Zon(2), Jan Köster(2)