Wojciech J. Stec

Amicus Therapeutics (United Kingdom) — United Kingdom

Chemistry · Physical Sciences

47h-index8.9kcitations493works1.12yr avg
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Research Topics

Organophosphorus compounds synthesis(206), DNA and Nucleic Acid Chemistry(139), Synthesis and Reactivity of Sulfur-Containing Compounds(106), HIV/AIDS drug development and treatment(63), Phosphorus compounds and reactions(55)

Publications493 total

Mode of action of a DCAF16-recruiting targeted glue that can selectively degrade BRD9
Nature Communications·2025· 6 citedOpen Access
The Comprehensive Review of Deviated Septum: Anatomy, Diagnosis, and Treatment Approaches
Quality in Sport·2025Open Access
Selective degradation of BRD9 by a DCAF16-recruiting targeted glue: mode of action elucidation and in vivo proof of concept
2025· 2 cited
Advancements in Pancreatic Cancer Treatment: A Comprehensive Review of Current Therapies and Future Directions
Quality in Sport·2024Open Access
Medical and health benefits of noise reduction at Intensive Care Units
Quality in Sport·2024Open Access
Endometriosis in Focus: Modern Therapeutic Approaches for Enhanced Patient Outcomes - Review
Quality in Sport·2024· 1 citedOpen Access
E-Cigarettes in Smoking Cessation and Harm Reduction: A Comprehensive Review of Recent Evidence and Potential Risks
Quality in Sport·2024Open Access
latest treatment of colorectal cancer - a review paper
Quality in Sport·2024Open Access
Protection of Distribution Grid with DER and IEEE1547.2-2023 Protection Guidance
2024· 1 cited
Cryo-EM structure of the human α1β3γ2 GABAA receptor in a lipid bilayer
Nature·2018· 332 citedOpen Access
Cryo-EM structure of the human synaptic alpha1-beta3-gamma2 GABAA receptor in complex with Megabody38 in a lipid nanodisc
2018· 5 cited
High-level production and purification in a functional state of an extrasynaptic gamma-aminobutyric acid type A receptor containing α4β3δ subunits
PLoS ONE·2018· 5 citedOpen Access
Cyclic<i>trans</i>-phosphorylation in a homodimer as the predominant mechanism of EGFRvIII action and regulation
Oncotarget·2018· 9 citedOpen Access
Low Incidence along with Low mRNA Levels of <i>EGFR<sup>vIII</sup></i> in Prostate and Colorectal Cancers Compared to Glioblastoma
Journal of Cancer·2017· 16 citedOpen Access
The α-thio and/or β-γ-hypophosphate analogs of ATP as cofactors of T4 DNA ligase
Bioorganic Chemistry·2016· 10 cited
IDH1R132H in Neural Stem Cells: Differentiation Impaired by Increased Apoptosis
PLoS ONE·2016· 19 citedOpen Access
Cell line with endogenous EGFRvIII expression is a suitable model for research and drug development purposes
Oncotarget·2016· 27 citedOpen Access
Mechanisms of JAK/STAT pathway negative regulation by the short coreceptor Eye Transformer/Latran
Molecular Biology of the Cell·2015· 11 citedOpen Access
Acyclic analogs of nucleosides based on tris(hydroxymethyl)phosphine oxide: synthesis and incorporation into short DNA oligomers
Heterocyclic Communications·2015· 4 citedOpen Access
Interactions of cellular histidine triad nucleotide binding protein 1 with nucleosides 5′-O-monophosphorothioate and their derivatives — Implication for desulfuration process in the cell
Biochimica et Biophysica Acta (BBA) - General Subjects·2014· 13 cited
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Frequent Co-authors

Maria Koziołkiewicz(11), Janina Baraniak(9), Piotr Guga(6), Wayne E. Morgan(4), John R. Van Wazer(4), Gerald Zon(4), Bernd Jastorff(4), Bogdan Uznański(4), Anna Kobylańska(4), Bolesław T. Karwowski(4), And̀rzej Okruszek(4), Andrzej Wilk(4), Małgorzata Boczkowska(4), Andrzej Grajkowski(3), R. Kinas(3), Krzysztof W. Pankiewicz(2), Roel van Driel(2), R. G. Albridge(2), Konrad Misiura(2), René J.W. de Wit(2)