Adolfo Garcı́a-Sastre

Office of Infectious Diseases — United States

Medicine · Health Sciences

161h-index103.1kcitations1.1kworks6.92yr avg
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Research Topics

Influenza Virus Research Studies(464), interferon and immune responses(308), Respiratory viral infections research(213), SARS-CoV-2 and COVID-19 Research(206), Immune Response and Inflammation(169)

Publications1.1k total

Discovery of Coronavirus Main Protease Inhibitors with Enhanced Brain Exposure and Potent Oral Efficacy in SARS-CoV-2 and MERS Infection Models
Journal of Medicinal Chemistry·2026Open Access
Innate antiviral readiness drives the expansion of protective T stem cell memory against influenza
2025Open Access
Immunogenicity and efficacy of homologous and heterologous NDV and MVA SARS-CoV-2 vaccines in mice and hamsters
npj Vaccines·2025Open Access
Autoantibodies neutralizing type I IFNs in a fatal case of H5N1 avian influenza
The Journal of Experimental Medicine·2025· 1 citedOpen Access
The role of co-infection in the pathogenesis of acute SARS-CoV-2 infection and development of post-acute sequelae: A perspective
eLife·2025Open Access
897 Infectious bursal disease virus (IBDV) as a novel virotherapy for stimulating innate and adaptive immune responses in different murine cancer models
Regular and Young Investigator Award Abstracts·2025Open Access
Antibody signatures of COVID-19 protection 3824
The Journal of Immunology·2025Open Access
632  <i>In situ</i> APMV-4 vaccination achieves systemic tumor clearance and long-term antitumor immunity, priming response to sub-therapeutic dosing of aCTLA-4 in colorectal carcinoma
Regular and Young Investigator Award Abstracts·2025Open Access
Infectious bursal disease virus (IBDV) as a novel oncolytic virotherapy in glioblastoma
Journal for ImmunoTherapy of Cancer·2025Open Access
Th2 immune responses promote anti-viral and anti-inflammatory activity during mild COVID-19 9405
The Journal of Immunology·2025Open Access
892 Pre-existing immunity boosts therapeutic efficacy of oncolytic influenza a virus in the presence and absence of neutralizing antibodies
Regular and Young Investigator Award Abstracts·2025Open Access
Pre-existing immunity levels are essential for expanding long-lived influenza-specific memory CD8 T-cells following vaccination 2634
The Journal of Immunology·2025Open Access
A cocktail of SARS-CoV-2 spike stem helix domain and receptor binding domain human monoclonal antibodies prevent the emerge of viral escape mutants
2025Open Access
ISG15 Differentially Modulates Clade Ib and II MPXV Infection
2025Open Access
Bioluminescent reporter influenza A viruses to track viral infections
Microbiology Spectrum·2025· 2 citedOpen Access
Entry, replication and innate immunity evasion of BANAL-236, a SARS-CoV-2-related bat virus, in <i>Rhinolophus</i> and human cells
2025Open Access
ISG15 Differentially Modulates Clade Ib and II MPXV Infection in MEF cells
2025Open Access
Integrative multi-omics analysis in vivo identifies influenza virus host factors
iScience·2025Open Access
Swine influenza-modified pulmonary microbiota
Frontiers in Cellular and Infection Microbiology·2025Open Access
Lymphangiogenesis driven by VEGF-C reshapes tumor immune landscape and enables tumor eradication by viral immunotherapy
2025Open Access
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Frequent Co-authors

Peter Palese(14), Randy A. Albrecht(9), Christopher F. Basler(7), Luis Martínez‐Sobrido(7), Lisa Miorin(6), Kris M. White(6), Florian Krammer(5), Terrence M. Tumpey(5), Nevan J. Krogan(5), Michael Schotsaert(5), Viviana Simon(4), Megan L. Shaw(4), David E. Swayne(4), Jacqueline M. Katz(4), Lars Pache(4), Sumit K. Chanda(4), Giulio Kleiner(3), Teresa Aydillo(3), Alicia Solórzano(3), Jeffery K. Taubenberger(3)