Monika Lamparska‐Przybysz

Celon Pharma (Poland) — Poland

Biochemistry, Genetics and Molecular Biology · Life Sciences

10h-index542citations35works3.02yr avg
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Research Topics

Wnt/β-catenin signaling in development and cancer(8), Cancer-related gene regulation(8), Cytokine Signaling Pathways and Interactions(5), Kruppel-like factors research(4), Cell death mechanisms and regulation(3)

Publications35 total

Preclinical characterization of CPL304110 as a potent and selective inhibitor of fibroblast growth factor receptors 1, 2, and 3 for gastric, bladder, and squamous cell lung cancer
Frontiers in Oncology·2024· 3 citedOpen Access
Design, Synthesis, and Development of pyrazolo[1,5-a]pyrimidine Derivatives as a Novel Series of Selective PI3Kδ Inhibitors: Part I—Indole Derivatives
Pharmaceuticals·2022· 4 citedOpen Access
Evaluation of the innovativeness of the domestic pharmaceutical sector projects within the framework of the R&D support programs
Farmacja Polska·2022Open Access
Discovery and optimization of novel pyrazole-benzimidazole CPL304110, as a potent and selective inhibitor of fibroblast growth factor receptors FGFR (1–3)
European Journal of Medicinal Chemistry·2020· 45 citedOpen Access
Differences in gene expression and alterations in cell cycle of acute myeloid leukemia cell lines after treatment with JAK inhibitors
European Journal of Pharmacology·2015· 4 cited
Cell-based assay for low- and high-scale screening of the Wnt/β-catenin signaling modulators
Analytical Biochemistry·2015· 7 cited
Discovery of TRAF-2 and NCK-interacting kinase (TNIK) inhibitors by ligand-based virtual screening methods
MedChemComm·2015· 6 cited
Epithelial–mesenchymal transition confers resistance to selective FGFR inhibitors in SNU-16 gastric cancer cells
Gastric Cancer·2014· 69 citedOpen Access
Inhibition of JAK/STAT pathway in airway epithelium as a potential targeted therapy of asthma
2014· 1 cited
Preclinical characterization of CPL-302-201, a novel, highly potent and selective PI3Kδ inhibitor for the treatment of inflammatory disorders
2014
Therapeutic potential of CPL-407-105 – Novel potent JAK/STAT pathway inhibitor for the treatment of asthma
2014
P1‐024: CHARACTERIZATION OF A NOVEL GROUP OF PHOSPHODIESTERASE 9A INHIBITORS AS PUTATIVE THERAPEUTICS FOR COGNITIVE DYSFUNCTION
Alzheimer s & Dementia·2014Open Access
Activating mutations in ALK kinase domain confer resistance to structurally unrelated ALK inhibitors in NPM-ALK-positive anaplastic large-cell lymphoma
Journal of Cancer Research and Clinical Oncology·2014· 36 citedOpen Access
Wnt/β-catenin pathway as a potential prognostic and predictive marker in patients with advanced ovarian cancer
Journal of Ovarian Research·2014· 80 citedOpen Access
395 Discovery of CPL-407-22 – Novel, Potent and Highly Selective JAK2 Kinase Inhibitor
European Journal of Cancer·2012
WNT-2, But not WNT-1 Expression Increases During Tumorgenesis in Breast, Prostate, Lung Cancer and Melanoma
Annals of Oncology·2012Open Access
1048 Gene Silencing of -catenin Inhibits Growth of Wnt/ß-catenin Pathway Dependent Colon Cancer Cell Lines
European Journal of Cancer·2012
1016 NPM-ALK I1171T Mutation Confers Resistance to Crizotinib in Anaplastic Large Cell Lymphoma
European Journal of Cancer·2012
1031 Differential Gene Expression Profile in Response to the Treatment With JAK2 Inhibitors – Ruxolitinib, SAR302503 and LY2784544
European Journal of Cancer·2012Open Access
Prognostic Significance of Wnt-1, β-catenin and E-cadherin Expression in Advanced Colorectal Carcinoma
Pathology & Oncology Research·2011· 77 citedOpen Access
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Frequent Co-authors

Maciej Wieczorek(22), Aleksandra Stańczak(13), Paweł Gunerka(12), Daria Zdżalik-Bielecka(12), Barbara Dymek(10), Karolina Dzwonek(10), Paulina Grygielewicz(9), Anna Bujak(9), Krzysztof Dubiel(9), T. Motyl(7), Joanna Hucz‐Kalitowska(6), Piotr Guzenda(5), Maria Majorek(5), Filip Stefaniak(5), Lubomir Bodnar(4), B Gajkowska(4), Mikołaj Matłoka(4), Monika Skupińska(4), Maria Wieczorek(4), Wojciech Kozłowski(3)