Warren E. Glaab

Merck & Co., Inc., Rahway, NJ, USA (United States) — United States

Biochemistry, Genetics and Molecular Biology · Life Sciences

24h-index2.5kcitations67works2.32yr avg
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Research Topics

DNA Repair Mechanisms(12), Chronic Kidney Disease and Diabetes(10), Genetic factors in colorectal cancer(9), Acute Kidney Injury Research(8), Drug Transport and Resistance Mechanisms(7)

Publications67 total

Biomarkers of Drug‐Induced Kidney Injury: Use in Clinical Trials and Recent Examples of Impact on Drug Development
Clinical Pharmacology & Therapeutics·2025Open Access
P06-22 Assay validation and quantification of novel urinary kidney safety biomarker candidates for the detection of glomerular injury in clinical specimens
Toxicology Letters·2025
P04-17 Cross-Species Immunoassays for Detection of Translational Safety Biomarkers in Drug-Induced Kidney Injury
Toxicology Letters·2025Open Access
LINE-1 transposition into murine Thyroglobulin results in congenital thyroid dysplasia
PLoS ONE·2025Open Access
Neurobiomarkers: Basic Aspects and Their Relevance in Nonclinical Studies
Toxicologic Pathology·2025· 1 cited
The challenge to identify sensitive safety biomarkers of peripheral neurotoxicity in the rat: A collaborative effort across industry and academia (IMI NeuroDeRisk project)
Toxicology·2024· 3 citedOpen Access
Magnitude of Urine Albumin and KIM-1 Changes Can be Used to Differentiate Glomerular Injury From Tubular Injury in Rats
Toxicologic Pathology·2024· 2 citedOpen Access
Performance of biomarkers NF-L, NSE, Tau and GFAP in blood and cerebrospinal fluid in rat for the detection of nervous system injury
Frontiers in Neuroscience·2024· 13 citedOpen Access
A mechanistic biomarker investigation of fialuridine hepatotoxicity using the chimeric TK-NOG Hu-liver mouse model and in vitro micropatterned hepatocyte cocultures
Toxicology Research·2024· 2 citedOpen Access
Neurofilament light chain in plasma as a sensitive diagnostic biomarker of peripheral neurotoxicity: In Vivo mouse studies with oxaliplatin and paclitaxel - NeuroDeRisk project
Biomedicine & Pharmacotherapy·2023· 8 citedOpen Access
Early-Onset albuminuria and Associated Renal Pathology in Leucine-Rich Repeat Kinase 2 Knockout Rats
Toxicologic Pathology·2023· 4 cited
Plasma biomarkers TAP, CPA1, and CPA2 for the detection of pancreatic injury in rat: the development of a novel multiplex IA-LC-MS/MS assay and biomarker performance evaluation
Archives of Toxicology·2022· 5 citedOpen Access
Universal Accessible Biomarkers of Drug-Induced Tissue Injury and Systemic Inflammation in Rat: Performance Assessment of TIMP-1, A2M, AGP, NGAL, and Albumin
Toxicological Sciences·2022· 8 cited
A MicroRNA Next-Generation-Sequencing Discovery Assay (miND) for Genome-Scale Analysis and Absolute Quantitation of Circulating MicroRNA Biomarkers
International Journal of Molecular Sciences·2022· 54 citedOpen Access
Kidney Injury Monitoring in Tobramycin-Treated Rhesus Monkeys: Supplementing Urinary Kidney Biomarkers With Kidney Biopsy Gene Expression Profiling
Toxicologic Pathology·2021· 1 cited
Systems analysis of miRNA biomarkers to inform drug safety
Archives of Toxicology·2021· 26 citedOpen Access
Universal Toxicity Gene Signatures for Early Identification of Drug-Induced Tissue Injuries in Rats
Toxicological Sciences·2021· 24 cited
The use of emerging safety biomarkers in nonclinical and clinical safety assessment – The current and future state: An IQ DruSafe industry survey
Regulatory Toxicology and Pharmacology·2020· 4 citedOpen Access
The use of emerging safety biomarkers in nonclinical and clinical safety assessment—the current and future state: An IQ DruSafe industry survey
Journal of Pharmacological and Toxicological Methods·2020
Characterization of indoleamine-2,3-dioxygenase 1, tryptophan-2,3-dioxygenase, and Ido1/Tdo2 knockout mice
Toxicology and Applied Pharmacology·2020· 9 cited
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Frequent Co-authors

Frank D. Sistare(21), Kateřina Vlasáková(19), Thomas R. Skopek(12), Wendy J. Bailey(9), Nagaraja Muniappa(7), Zoltán Erdős(7), Sean P. Troth(6), Daniel Holder(6), Kenneth R. Tindall(6), Asad Umar(5), John I. Risinger(5), J. Carl Barrett(5), Thomas A. Kunkel(5), Kara Pearson(5), Keith Q. Tanis(5), Joseph F. Sina(4), Yi‐Zhong Gu(4), Pamela Lane(4), Raymond J. Gonzalez(4), Lisa LaFranco-Scheuch(4)